| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.160088 |
| NDRG1 | N-myc downstream regulated 1 | 0.111759 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0660433 |
| GDF15 | growth differentiation factor 15 | 0.0609199 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0534197 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0526736 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0505758 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0500434 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0498028 |
| CD109 | CD109 molecule | 0.0467727 |
| HLA-B | major histocompatibility complex, class I, B | 0.0421772 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0421178 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0420942 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0367225 |
| EGR1 | early growth response 1 | 0.0361414 |
| ADM | adrenomedullin | 0.035812 |
| RNF145 | ring finger protein 145 | 0.0357466 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.034219 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0337676 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0337505 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333731 |
| PTMA | prothymosin, alpha | 0.0318639 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0289919 |
| CABIN1 | calcineurin binding protein 1 | 0.0284561 |
| RPLP1 | ribosomal protein, large, P1 | 0.0280484 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0280101 |
| GOLGA4 | golgin A4 | 0.0266861 |
| RPL37A | ribosomal protein L37a | 0.025864 |
| RPS19 | ribosomal protein S19 | 0.0257763 |
| RPLP2 | ribosomal protein, large, P2 | 0.0256629 |
| RPL35A | ribosomal protein L35a | 0.0254287 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251228 |
| RPS6 | ribosomal protein S6 | 0.0250013 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0248623 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0248575 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0245529 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0243341 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0242633 |
| RPS12 | ribosomal protein S12 | 0.024009 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0239984 |
| RPL12 | ribosomal protein L12 | 0.0239872 |
| PLIN2 | perilipin 2 | 0.0238333 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0230564 |
| S100A9 | S100 calcium binding protein A9 | 0.0229416 |
| INSIG1 | insulin induced gene 1 | 0.0228219 |
| RPS8 | ribosomal protein S8 | 0.0226593 |
| RPS2 | ribosomal protein S2 | 0.0225324 |
| S100A6 | S100 calcium binding protein A6 | 0.0224438 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0221971 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0220818 |
| RNF24 | ring finger protein 24 | 0.0220004 |
| PHF21A | PHD finger protein 21A | 0.0218213 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0218057 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0214806 |
| YBX1 | Y box binding protein 1 | 0.021353 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0208665 |
| TPI1 | triosephosphate isomerase 1 | 0.0207924 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0205521 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0204564 |
| RPLP0 | ribosomal protein, large, P0 | 0.0202723 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0202689 |
| FTL | ferritin, light polypeptide | 0.0201049 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0201035 |
| RLF | rearranged L-myc fusion | 0.0199195 |
| CDC73 | cell division cycle 73 | 0.0198325 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0198135 |
| SFTPA2 | surfactant protein A2 | 0.0196784 |
| CTTNBP2 | cortactin binding protein 2 | 0.0196024 |
| PTK2 | protein tyrosine kinase 2 | 0.0195204 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0192651 |
| RPL11 | ribosomal protein L11 | 0.0192501 |
| CSNK1E | casein kinase 1, epsilon | 0.0192117 |
| HELZ | helicase with zinc finger | 0.0191494 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0190007 |
| TPD52 | tumor protein D52 | 0.0188956 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0187425 |
| RPL21 | ribosomal protein L21 | 0.0187334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0186813 |
| USP37 | ubiquitin specific peptidase 37 | 0.0185669 |
| SEC24A | SEC24 family member A | 0.0185107 |
| HLA-E | major histocompatibility complex, class I, E | 0.0184157 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0184086 |
| CALD1 | caldesmon 1 | 0.0183532 |
| RPL36 | ribosomal protein L36 | 0.0183256 |
| PTCHD4 | patched domain containing 4 | 0.0183184 |
| VEGFA | vascular endothelial growth factor A | 0.0178522 |
| MTDH | metadherin | 0.0176815 |
| GNAS | GNAS complex locus | 0.0175998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0175629 |
| RPL19 | ribosomal protein L19 | 0.0174966 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0172695 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0172651 |
| RPS20 | ribosomal protein S20 | 0.0172636 |
| ARF1 | ADP-ribosylation factor 1 | 0.0172486 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0172465 |
| HLA-C | major histocompatibility complex, class I, C | 0.0172062 |
| RPL8 | ribosomal protein L8 | 0.0170487 |
| CALR | calreticulin | 0.0170055 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0168854 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0167753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.137116 |
| UBC | ubiquitin C | -0.132861 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.113076 |
| FN1 | fibronectin 1 | -0.112746 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.112182 |
| VIM | vimentin | -0.108257 |
| ASPH | aspartate beta-hydroxylase | -0.090965 |
| FMN1 | formin 1 | -0.0816283 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0724655 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0681072 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0667957 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0625351 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0607388 |
| GPC6 | glypican 6 | -0.0596842 |
| AHNAK | AHNAK nucleoprotein | -0.0594398 |
| ZYX | zyxin | -0.0575537 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.057253 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0511357 |
| ENO1 | enolase 1, (alpha) | -0.0508192 |
| PCDH7 | protocadherin 7 | -0.0454984 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0419416 |
| TMEM178B | transmembrane protein 178B | -0.0418984 |
| PCBP2 | poly(rC) binding protein 2 | -0.0407678 |
| VMP1 | vacuole membrane protein 1 | -0.03982 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0372104 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0369693 |
| LDHA | lactate dehydrogenase A | -0.0368681 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.036105 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0344796 |
| FRMD4A | FERM domain containing 4A | -0.0344783 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0343304 |
| IL6ST | interleukin 6 signal transducer | -0.0340968 |
| SRPK2 | SRSF protein kinase 2 | -0.03351 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0326905 |
| APP | amyloid beta (A4) precursor protein | -0.0319335 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.031693 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0312768 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312713 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0308701 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0308261 |
| NHSL1 | NHS-like 1 | -0.0308216 |
| GAS7 | growth arrest-specific 7 | -0.0306818 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0300127 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0299872 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0297917 |
| ACTN1 | actinin, alpha 1 | -0.0296981 |
| ACTN4 | actinin, alpha 4 | -0.0295361 |
| SETBP1 | SET binding protein 1 | -0.029191 |
| LAMB1 | laminin, beta 1 | -0.0290923 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0288125 |
| MACROD2 | MACRO domain containing 2 | -0.0285672 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0279388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0278603 |
| RO60 | Ro60, Y RNA binding protein | -0.0273756 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.02693 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0268816 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0268407 |
| PI15 | peptidase inhibitor 15 | -0.0267793 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0263286 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.026093 |
| AHR | aryl hydrocarbon receptor | -0.0259914 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0259432 |
| HMCN1 | hemicentin 1 | -0.0257588 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0249776 |
| PKM | pyruvate kinase, muscle | -0.0249444 |
| DUSP6 | dual specificity phosphatase 6 | -0.0248805 |
| CLIC4 | chloride intracellular channel 4 | -0.0248689 |
| SDC2 | syndecan 2 | -0.0239963 |
| PRELID2 | PRELI domain containing 2 | -0.0229871 |
| SFPQ | splicing factor proline/glutamine-rich | -0.022981 |
| EXOC4 | exocyst complex component 4 | -0.0228683 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022823 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0227545 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0223885 |
| TAGLN2 | transgelin 2 | -0.0223186 |
| FBXO32 | F-box protein 32 | -0.0221017 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0220754 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0217705 |
| EXOC6B | exocyst complex component 6B | -0.0212434 |
| RCAN1 | regulator of calcineurin 1 | -0.0210497 |
| TNNC1 | troponin C type 1 (slow) | -0.021044 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0209395 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0208262 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0207915 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0205787 |
| RTN4 | reticulon 4 | -0.0203925 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201949 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0201569 |
| TRIM9 | tripartite motif containing 9 | -0.0200681 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0199282 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0197624 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0196841 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0196627 |
| ENAH | enabled homolog (Drosophila) | -0.0193856 |
| ETV1 | ets variant 1 | -0.0193452 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.019179 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0191766 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.019108 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0190137 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.018832 |