| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.177642 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0830116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0796439 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0784471 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0653067 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0613946 |
| CD2AP | CD2-associated protein | 0.060797 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.060412 |
| MT2A | metallothionein 2A | 0.0599891 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0561961 |
| MT1X | metallothionein 1X | 0.0555123 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0552361 |
| SPAG9 | sperm associated antigen 9 | 0.0532582 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0524453 |
| CCNL1 | cyclin L1 | 0.049784 |
| SMAD3 | SMAD family member 3 | 0.0477156 |
| TGM2 | transglutaminase 2 | 0.046379 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0434812 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0426332 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0399153 |
| RTN4 | reticulon 4 | 0.039131 |
| ASPH | aspartate beta-hydroxylase | 0.0374318 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0371298 |
| FAM13A | family with sequence similarity 13, member A | 0.0364752 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0362739 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0361408 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0359253 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0356719 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0354199 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0343192 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0323569 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0309909 |
| APP | amyloid beta (A4) precursor protein | 0.0309021 |
| KRT18 | keratin 18, type I | 0.0306253 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0299012 |
| CCNY | cyclin Y | 0.0297807 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297766 |
| MEF2A | myocyte enhancer factor 2A | 0.0289148 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0287261 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0284063 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0284011 |
| FAM3C | family with sequence similarity 3, member C | 0.0277533 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0275075 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0273632 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.027206 |
| YTHDC1 | YTH domain containing 1 | 0.0267942 |
| PDZD8 | PDZ domain containing 8 | 0.0266824 |
| TOP1 | topoisomerase (DNA) I | 0.0266368 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0265255 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0260269 |
| EHBP1 | EH domain binding protein 1 | 0.0255551 |
| YBX1 | Y box binding protein 1 | 0.0253986 |
| ABI1 | abl-interactor 1 | 0.0249813 |
| ZNF292 | zinc finger protein 292 | 0.0247341 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245772 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0243891 |
| OGA | O-GlcNAcase | 0.0240659 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0239814 |
| HLA-C | major histocompatibility complex, class I, C | 0.0239137 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0235655 |
| PHF3 | PHD finger protein 3 | 0.0234452 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0234308 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0233688 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0231683 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0230145 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0226654 |
| TPM3 | tropomyosin 3 | 0.0225186 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.022458 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0224543 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0224438 |
| KLF6 | Kruppel-like factor 6 | 0.0224352 |
| RNF149 | ring finger protein 149 | 0.0224155 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223045 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0221255 |
| PLEC | plectin | 0.0221028 |
| FLNA | filamin A, alpha | 0.0218645 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0217684 |
| PNN | pinin, desmosome associated protein | 0.0215431 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0213643 |
| ANO6 | anoctamin 6 | 0.0212341 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0209478 |
| MYO5B | myosin VB | 0.0207855 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0206631 |
| BCL2L1 | BCL2-like 1 | 0.0202422 |
| NOTCH2 | notch 2 | 0.019787 |
| DSG2 | desmoglein 2 | 0.019435 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0192544 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0192218 |
| HELZ | helicase with zinc finger | 0.0190876 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0188695 |
| DST | dystonin | 0.0188407 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.018804 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.018671 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0181061 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0179993 |
| MAP1B | microtubule-associated protein 1B | 0.0178755 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0177448 |
| TMEM51 | transmembrane protein 51 | 0.0177171 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0176634 |
| NEK7 | NIMA-related kinase 7 | 0.0175634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.155668 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.119628 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116115 |
| PTMA | prothymosin, alpha | -0.113194 |
| B2M | beta-2-microglobulin | -0.106645 |
| TMSB10 | thymosin beta 10 | -0.105338 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0954254 |
| MMP7 | matrix metallopeptidase 7 | -0.0868502 |
| RPL35A | ribosomal protein L35a | -0.0857973 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0822382 |
| FTL | ferritin, light polypeptide | -0.0739207 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0730776 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0561978 |
| LCN2 | lipocalin 2 | -0.0552142 |
| CP | ceruloplasmin (ferroxidase) | -0.0546527 |
| PLAT | plasminogen activator, tissue | -0.0541233 |
| RPL23 | ribosomal protein L23 | -0.0537366 |
| KRT19 | keratin 19, type I | -0.0534347 |
| ACTG1 | actin gamma 1 | -0.0532259 |
| HLA-A | major histocompatibility complex, class I, A | -0.0523829 |
| RPL31 | ribosomal protein L31 | -0.0508279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494248 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0439478 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0438874 |
| RPS8 | ribosomal protein S8 | -0.0436477 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0425912 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0425777 |
| RPLP1 | ribosomal protein, large, P1 | -0.0408653 |
| S100A6 | S100 calcium binding protein A6 | -0.0404455 |
| S100A10 | S100 calcium binding protein A10 | -0.0398748 |
| UBC | ubiquitin C | -0.0396128 |
| PKM | pyruvate kinase, muscle | -0.0392721 |
| GNAS | GNAS complex locus | -0.0374916 |
| RPS29 | ribosomal protein S29 | -0.0373538 |
| VIM | vimentin | -0.0368511 |
| FBXO11 | F-box protein 11 | -0.0365317 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.036343 |
| TPM4 | tropomyosin 4 | -0.0363133 |
| HMGA1 | high mobility group AT-hook 1 | -0.0361689 |
| ANXA2 | annexin A2 | -0.0359468 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0356311 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.034125 |
| RPS25 | ribosomal protein S25 | -0.0332316 |
| RPL34 | ribosomal protein L34 | -0.0332196 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0317188 |
| INTS6 | integrator complex subunit 6 | -0.0314752 |
| IER3 | immediate early response 3 | -0.0310646 |
| CSTB | cystatin B (stefin B) | -0.0306496 |
| APOL1 | apolipoprotein L, 1 | -0.0305668 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0305444 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.03052 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0301126 |
| S100P | S100 calcium binding protein P | -0.0298567 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0296525 |
| RPS14 | ribosomal protein S14 | -0.0291182 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0290578 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0290575 |
| LAMB3 | laminin, beta 3 | -0.0286251 |
| RPS24 | ribosomal protein S24 | -0.0283305 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.028029 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0273975 |
| RPL37A | ribosomal protein L37a | -0.0273461 |
| S100A11 | S100 calcium binding protein A11 | -0.0264316 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0257893 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256178 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0253403 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0251391 |
| DTNA | dystrobrevin, alpha | -0.025117 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0250405 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0248277 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0246443 |
| LDHA | lactate dehydrogenase A | -0.0246101 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0244912 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0243743 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.023946 |
| TMC5 | transmembrane channel-like 5 | -0.0239055 |
| HM13 | histocompatibility (minor) 13 | -0.0234398 |
| RPS27A | ribosomal protein S27a | -0.0233791 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0232 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.022407 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0220852 |
| TFF2 | trefoil factor 2 | -0.0220632 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0219688 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0218787 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0217697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.021678 |
| SP100 | SP100 nuclear antigen | -0.0216726 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0216097 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0215119 |
| FUS | FUS RNA binding protein | -0.0214815 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0213835 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0212069 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0211706 |
| STC1 | stanniocalcin 1 | -0.0210848 |
| LMNA | lamin A/C | -0.0208022 |
| CD63 | CD63 molecule | -0.020748 |
| MORF4L2 | mortality factor 4 like 2 | -0.0207202 |
| NABP1 | nucleic acid binding protein 1 | -0.0206438 |
| SQSTM1 | sequestosome 1 | -0.0205408 |
| FAM107B | family with sequence similarity 107, member B | -0.0204393 |
