| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.180024 |
| FAM13A | family with sequence similarity 13, member A | 0.10725 |
| HELZ | helicase with zinc finger | 0.106575 |
| MEF2A | myocyte enhancer factor 2A | 0.0918767 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0827436 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0799623 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0655712 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0608601 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0588243 |
| NDRG1 | N-myc downstream regulated 1 | 0.0556641 |
| SEPTIN9 | septin 9 | 0.0556513 |
| LPIN1 | lipin 1 | 0.0519007 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.050557 |
| DTNA | dystrobrevin, alpha | 0.0497853 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0482315 |
| WDR45B | WD repeat domain 45B | 0.0439781 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427673 |
| FNBP1 | formin binding protein 1 | 0.0404108 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0391706 |
| SMAD3 | SMAD family member 3 | 0.0390423 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.038958 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357734 |
| OGA | O-GlcNAcase | 0.0344099 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340407 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0334863 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0328322 |
| COPA | coatomer protein complex, subunit alpha | 0.0320666 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0315621 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0314316 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0311079 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.031047 |
| MSI2 | musashi RNA-binding protein 2 | 0.0306726 |
| USP3 | ubiquitin specific peptidase 3 | 0.0305562 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0298612 |
| SSBP3 | single stranded DNA binding protein 3 | 0.029813 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297956 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0296486 |
| ASPH | aspartate beta-hydroxylase | 0.0292931 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0291945 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0288974 |
| GOLGA4 | golgin A4 | 0.028742 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0287254 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0286775 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286641 |
| TOP1 | topoisomerase (DNA) I | 0.0282597 |
| VEGFA | vascular endothelial growth factor A | 0.0279878 |
| USP34 | ubiquitin specific peptidase 34 | 0.0275967 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0274789 |
| RNF145 | ring finger protein 145 | 0.0274569 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0274535 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0265686 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265544 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0263326 |
| DNMBP | dynamin binding protein | 0.0261352 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0258943 |
| XPO1 | exportin 1 | 0.0258671 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.025677 |
| NUP58 | nucleoporin 58 | 0.0253663 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0252829 |
| PTK2 | protein tyrosine kinase 2 | 0.025198 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0248224 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0245967 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0245764 |
| CDH13 | cadherin 13 | 0.0245022 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0237634 |
| CENPF | centromere protein F, 350/400kDa | 0.0232824 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0232734 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0232625 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0230686 |
| PHIP | pleckstrin homology domain interacting protein | 0.0230336 |
| TRIB2 | tribbles pseudokinase 2 | 0.0229222 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0226619 |
| AFDN | afadin, adherens junction formation factor | 0.0224745 |
| E2F7 | E2F transcription factor 7 | 0.022446 |
| SETD5 | SET domain containing 5 | 0.0222456 |
| ENAH | enabled homolog (Drosophila) | 0.0220824 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0218268 |
| JMJD1C | jumonji domain containing 1C | 0.021661 |
| LOXL2 | lysyl oxidase-like 2 | 0.0214601 |
| QKI | QKI, KH domain containing, RNA binding | 0.0213985 |
| PKM | pyruvate kinase, muscle | 0.0211679 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0211021 |
| GLG1 | golgi glycoprotein 1 | 0.0208801 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0208434 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0205495 |
| PREPL | prolyl endopeptidase-like | 0.0205391 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0205335 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205128 |
| ZNF292 | zinc finger protein 292 | 0.0204655 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0203585 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0203406 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0202401 |
| FLNB | filamin B, beta | 0.0202218 |
| ANXA2 | annexin A2 | 0.0200555 |
| RNF24 | ring finger protein 24 | 0.0199519 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0194923 |
| PDE8A | phosphodiesterase 8A | 0.0194632 |
| SQSTM1 | sequestosome 1 | 0.0194592 |
| CCNY | cyclin Y | 0.0193226 |
| DENND4C | DENN/MADD domain containing 4C | 0.0192915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.124524 |
| IGF2 | insulin-like growth factor 2 | -0.115808 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114227 |
| SYT1 | synaptotagmin I | -0.0994376 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.082724 |
| RPL19 | ribosomal protein L19 | -0.0813553 |
| NRG1 | neuregulin 1 | -0.0753505 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0730633 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0724876 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.064656 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0617825 |
| RPL23 | ribosomal protein L23 | -0.0584971 |
| COL1A1 | collagen, type I, alpha 1 | -0.0569509 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0517438 |
| ACTG1 | actin gamma 1 | -0.0512947 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0504138 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0501838 |
| TMSB10 | thymosin beta 10 | -0.0496061 |
| FRMD4A | FERM domain containing 4A | -0.0493975 |
| BPTF | bromodomain PHD finger transcription factor | -0.0493625 |
| RPL38 | ribosomal protein L38 | -0.0465962 |
| KLHL13 | kelch-like family member 13 | -0.0457849 |
| RPS6 | ribosomal protein S6 | -0.0454927 |
| VCL | vinculin | -0.0443144 |
| RNF213 | ring finger protein 213 | -0.0441355 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0440968 |
| TLE4 | transducin-like enhancer of split 4 | -0.0439445 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0428659 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0401546 |
| ZNF804A | zinc finger protein 804A | -0.0398939 |
| RPL35A | ribosomal protein L35a | -0.039442 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0394383 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0387653 |
| PLPP1 | phospholipid phosphatase 1 | -0.0387415 |
| RPL34 | ribosomal protein L34 | -0.0386318 |
| SIK2 | salt-inducible kinase 2 | -0.0380224 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0378774 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378694 |
| RPS19 | ribosomal protein S19 | -0.0370843 |
| RPS24 | ribosomal protein S24 | -0.0368223 |
| RPL7A | ribosomal protein L7a | -0.0360286 |
| RPL36 | ribosomal protein L36 | -0.0355146 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0348285 |
| CADM2 | cell adhesion molecule 2 | -0.0346887 |
| PTMA | prothymosin, alpha | -0.0328895 |
| RPL26 | ribosomal protein L26 | -0.0324213 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.032275 |
| RPL12 | ribosomal protein L12 | -0.0321526 |
| RPL37A | ribosomal protein L37a | -0.031781 |
| GLCCI1 | glucocorticoid induced 1 | -0.0312735 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0312402 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0311133 |
| RPLP0 | ribosomal protein, large, P0 | -0.030689 |
| RPS27A | ribosomal protein S27a | -0.0306796 |
| RPS29 | ribosomal protein S29 | -0.0305752 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0303859 |
| RPS23 | ribosomal protein S23 | -0.0303228 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0298776 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0293838 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0291919 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0290232 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0288732 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0288667 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0288517 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0287252 |
| RPS3 | ribosomal protein S3 | -0.0285536 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0283597 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0279966 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0273915 |
| RALYL | RALY RNA binding protein-like | -0.0273611 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.027317 |
| RPL36A | ribosomal protein L36a | -0.0271357 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0271155 |
| B2M | beta-2-microglobulin | -0.027007 |
| RPL27 | ribosomal protein L27 | -0.0269618 |
| RIGI | RNA sensor RIG-I | -0.0265014 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0263092 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0261804 |
| NREP | neuronal regeneration related protein | -0.0260599 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0258499 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.025657 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0255673 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0255368 |
| PDE10A | phosphodiesterase 10A | -0.0255259 |
| S100A9 | S100 calcium binding protein A9 | -0.0253105 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0252297 |
| SP100 | SP100 nuclear antigen | -0.0249955 |
| RPS27 | ribosomal protein S27 | -0.0248833 |
| TPM1 | tropomyosin 1 (alpha) | -0.0248022 |
| DNM3 | dynamin 3 | -0.0244089 |
| RPS15 | ribosomal protein S15 | -0.0243665 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.023955 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0237141 |
| RPS12 | ribosomal protein S12 | -0.02311 |
| FHIT | fragile histidine triad | -0.0230712 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0230373 |
| RPL31 | ribosomal protein L31 | -0.0227836 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0225916 |
| RPS21 | ribosomal protein S21 | -0.0221641 |
