| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.360526 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.110424 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0714267 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0665506 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0625712 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0615816 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0514413 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0498127 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0488705 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0462167 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0436588 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0428099 |
| PDS5B | PDS5 cohesin associated factor B | 0.037059 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0336804 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0315381 |
| APP | amyloid beta (A4) precursor protein | 0.0314602 |
| H2AC6 | H2A clustered histone 6 | 0.0309176 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0305285 |
| PAPOLA | poly(A) polymerase alpha | 0.029689 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296642 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0290847 |
| MOB4 | MOB family member 4, phocein | 0.0288109 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0286393 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0270543 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0270045 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0267236 |
| WAC | WW domain containing adaptor with coiled-coil | 0.026292 |
| RNF145 | ring finger protein 145 | 0.0255452 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0254378 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0251847 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0248559 |
| TOP1 | topoisomerase (DNA) I | 0.0246371 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0243566 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0242876 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0237614 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0232502 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0228424 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0224165 |
| CCNL1 | cyclin L1 | 0.0222432 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0217343 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0215911 |
| COPA | coatomer protein complex, subunit alpha | 0.021273 |
| NCKAP1 | NCK-associated protein 1 | 0.0207258 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0202541 |
| NOP58 | NOP58 ribonucleoprotein | 0.0196677 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0189494 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0188385 |
| RPL21 | ribosomal protein L21 | 0.0186773 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0186155 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0186115 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0185727 |
| BRD2 | bromodomain containing 2 | 0.018365 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0180675 |
| HBS1L | HBS1-like translational GTPase | 0.0177659 |
| CRY1 | cryptochrome circadian clock 1 | 0.0177056 |
| SCARB1 | scavenger receptor class B, member 1 | 0.017694 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0176847 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0176672 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0175585 |
| COLEC11 | collectin sub-family member 11 | 0.0175443 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0175062 |
| MXD1 | MAX dimerization protein 1 | 0.0174025 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0171312 |
| VEGFA | vascular endothelial growth factor A | 0.0171111 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0170568 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0168769 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0167235 |
| SPAG9 | sperm associated antigen 9 | 0.016713 |
| XPO1 | exportin 1 | 0.0166481 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0165685 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0164437 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0163313 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0158042 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0157399 |
| RPS6 | ribosomal protein S6 | 0.0155432 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0154331 |
| KLHL24 | kelch-like family member 24 | 0.015398 |
| GOLGA4 | golgin A4 | 0.0153785 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0152677 |
| SUGT1 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 0.0150446 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0149 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0148123 |
| RBM39 | RNA binding motif protein 39 | 0.0147725 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0147235 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0146381 |
| IPO7 | importin 7 | 0.0144119 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0143865 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 0.0143687 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0142997 |
| BRD4 | bromodomain containing 4 | 0.0140513 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.013985 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0138379 |
| HYOU1 | hypoxia up-regulated 1 | 0.0138143 |
| RPL37A | ribosomal protein L37a | 0.013787 |
| H2BC11 | H2B clustered histone 11 | 0.0135867 |
| USP3 | ubiquitin specific peptidase 3 | 0.0135415 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.013496 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0133245 |
| MATR3 | matrin 3 | 0.0132395 |
| SETD5 | SET domain containing 5 | 0.0130722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.14054 |
| B2M | beta-2-microglobulin | -0.123226 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.107049 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.101797 |
| RNF213 | ring finger protein 213 | -0.1007 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0834321 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0834089 |
| LCN2 | lipocalin 2 | -0.0827601 |
| XAF1 | XIAP associated factor 1 | -0.0764402 |
| SP100 | SP100 nuclear antigen | -0.0754227 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0727901 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0703326 |
| HLA-B | major histocompatibility complex, class I, B | -0.0701913 |
| MX2 | MX dynamin-like GTPase 2 | -0.0682803 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0660922 |
| PTMA | prothymosin, alpha | -0.0626945 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0622754 |
| RIGI | RNA sensor RIG-I | -0.0617255 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0610634 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0563369 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0551441 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0537434 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0536835 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0503601 |
| NCKAP5 | NCK-associated protein 5 | -0.0496022 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0474398 |
| LMO7 | LIM domain 7 | -0.0471177 |
| PERP | PERP, TP53 apoptosis effector | -0.0462389 |
| PLSCR1 | phospholipid scramblase 1 | -0.0455826 |
| TXNIP | thioredoxin interacting protein | -0.0453173 |
| MX1 | MX dynamin-like GTPase 1 | -0.0452319 |
| PRKCA | protein kinase C, alpha | -0.0430133 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0427996 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0412779 |
| VCL | vinculin | -0.0410719 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0407461 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0403921 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0400769 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0390467 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0387832 |
| FOXP1 | forkhead box P1 | -0.0387463 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0387362 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0383064 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0379699 |
| ABLIM1 | actin binding LIM protein 1 | -0.0379669 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0376446 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.03731 |
| SPATA13 | spermatogenesis associated 13 | -0.036942 |
| LYZ | lysozyme | -0.0366367 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0365718 |
| MUC20 | mucin 20, cell surface associated | -0.0360746 |
| PMP22 | peripheral myelin protein 22 | -0.0359935 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0359434 |
| ANXA2 | annexin A2 | -0.0357349 |
| AREG | amphiregulin | -0.0357069 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0356159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347923 |
| RAD51B | RAD51 paralog B | -0.03474 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0345398 |
| EPHB2 | EPH receptor B2 | -0.0345142 |
| MAP7 | microtubule-associated protein 7 | -0.0335855 |
| ASPH | aspartate beta-hydroxylase | -0.0335479 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0335188 |
| MYO1E | myosin IE | -0.0334672 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0332729 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0332245 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0329934 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0328826 |
| ATP11A | ATPase, class VI, type 11A | -0.0323964 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0322713 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0321644 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.032159 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.032144 |
| TMSB10 | thymosin beta 10 | -0.0318688 |
| APOL1 | apolipoprotein L, 1 | -0.0315538 |
| RUNX1 | runt-related transcription factor 1 | -0.0314318 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0309398 |
| PGK1 | phosphoglycerate kinase 1 | -0.0308091 |
| PHF3 | PHD finger protein 3 | -0.0307017 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0304227 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0301737 |
| EGR1 | early growth response 1 | -0.0295617 |
| KLF6 | Kruppel-like factor 6 | -0.028943 |
| RPL35A | ribosomal protein L35a | -0.0283367 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0282026 |
| ETV6 | ets variant 6 | -0.0279053 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0276809 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0275145 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.027279 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0272436 |
| FMN1 | formin 1 | -0.0270266 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0270089 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0269824 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.026792 |
| PRELID2 | PRELI domain containing 2 | -0.0267329 |
| JUN | jun proto-oncogene | -0.0265021 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0261954 |
| TRIM56 | tripartite motif containing 56 | -0.0261486 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0260201 |
| ERBIN | erbb2 interacting protein | -0.0257746 |
