| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.173043 |
| NDRG1 | N-myc downstream regulated 1 | 0.107474 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106352 |
| STC1 | stanniocalcin 1 | 0.0721364 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0651102 |
| EGFR | epidermal growth factor receptor | 0.0573723 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0569287 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0559435 |
| FAM13A | family with sequence similarity 13, member A | 0.0470239 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0452879 |
| FNIP1 | folliculin interacting protein 1 | 0.0446283 |
| HDAC9 | histone deacetylase 9 | 0.043983 |
| HELZ | helicase with zinc finger | 0.0426252 |
| GOLGB1 | golgin B1 | 0.0413437 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0411639 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0392397 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0390315 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0388724 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0386974 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0383418 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0379193 |
| PRELID2 | PRELI domain containing 2 | 0.0371049 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0357595 |
| OGA | O-GlcNAcase | 0.0347733 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0343069 |
| LRRC49 | leucine rich repeat containing 49 | 0.0342255 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0342246 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033809 |
| CANX | calnexin | 0.0329495 |
| ANK2 | ankyrin 2, neuronal | 0.0317106 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0314231 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0308377 |
| PHF3 | PHD finger protein 3 | 0.0299983 |
| FLNA | filamin A, alpha | 0.0295088 |
| ZNF395 | zinc finger protein 395 | 0.0294092 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0288296 |
| CADM1 | cell adhesion molecule 1 | 0.0286318 |
| INTS6 | integrator complex subunit 6 | 0.0282266 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0282141 |
| AHNAK | AHNAK nucleoprotein | 0.0280457 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0276958 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0264967 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0263055 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261534 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0258101 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255543 |
| SEC24D | SEC24 family member D | 0.0252333 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0248603 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0248238 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0247433 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0247144 |
| COG5 | component of oligomeric golgi complex 5 | 0.0246702 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0244783 |
| ATP13A3 | ATPase type 13A3 | 0.0241369 |
| CLTC | clathrin, heavy chain (Hc) | 0.0235021 |
| ASPH | aspartate beta-hydroxylase | 0.0230269 |
| SUCO | SUN domain containing ossification factor | 0.0225577 |
| COPA | coatomer protein complex, subunit alpha | 0.0224369 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0224329 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0223741 |
| SRP54 | signal recognition particle 54kDa | 0.0221366 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0219227 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0217067 |
| ZNF292 | zinc finger protein 292 | 0.0217012 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0216685 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0214668 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.021422 |
| GOLGA4 | golgin A4 | 0.0214034 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0213665 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0210244 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.021007 |
| TFG | TRK-fused gene | 0.0208371 |
| INSIG2 | insulin induced gene 2 | 0.0205964 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0205554 |
| VCL | vinculin | 0.0204421 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0202469 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0201915 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.020134 |
| HDLBP | high density lipoprotein binding protein | 0.0200381 |
| ZNF841 | zinc finger protein 841 | 0.0199535 |
| CDK13 | cyclin-dependent kinase 13 | 0.0199012 |
| CALR | calreticulin | 0.0198427 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0198018 |
| CD109 | CD109 molecule | 0.0197647 |
| TNNC1 | troponin C type 1 (slow) | 0.0197635 |
| SQSTM1 | sequestosome 1 | 0.0196719 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0195754 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0192846 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0190912 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0190048 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0186958 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0184784 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0182137 |
| CALD1 | caldesmon 1 | 0.0176973 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0176199 |
| TMEM39A | transmembrane protein 39A | 0.0173369 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0172818 |
| ADM | adrenomedullin | 0.0172327 |
| TMF1 | TATA element modulatory factor 1 | 0.0169152 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0166281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.128556 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.121404 |
| TMSB10 | thymosin beta 10 | -0.111637 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.102496 |
| B2M | beta-2-microglobulin | -0.0999074 |
| HLA-B | major histocompatibility complex, class I, B | -0.0971565 |
| VIM | vimentin | -0.0948894 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0923623 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0705573 |
| NLGN1 | neuroligin 1 | -0.0692782 |
| MT2A | metallothionein 2A | -0.0687675 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0671008 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0650273 |
| TPM4 | tropomyosin 4 | -0.0603118 |
| MKI67 | marker of proliferation Ki-67 | -0.0603082 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.051007 |
| TXNRD1 | thioredoxin reductase 1 | -0.0493213 |
| PRSS23 | protease, serine, 23 | -0.0488787 |
| PTK2 | protein tyrosine kinase 2 | -0.0480857 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0465983 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0463625 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0439428 |
| CENPF | centromere protein F, 350/400kDa | -0.0438605 |
| CD44 | CD44 molecule (Indian blood group) | -0.0427839 |
| IGF2 | insulin-like growth factor 2 | -0.0427515 |
| CLMP | CXADR-like membrane protein | -0.042538 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0417552 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0415118 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.041115 |
| POTEF | POTE ankyrin domain family, member F | -0.0399238 |
| NAV1 | neuron navigator 1 | -0.03752 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374389 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.036779 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0366318 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0355938 |
| ENO1 | enolase 1, (alpha) | -0.0346171 |
| CBX3 | chromobox homolog 3 | -0.0340217 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0334694 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0332159 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0331719 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0325973 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0316723 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316312 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0312756 |
| MAP1B | microtubule-associated protein 1B | -0.0308317 |
| TENM3 | teneurin transmembrane protein 3 | -0.03074 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0302225 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0301537 |
| KYNU | kynureninase | -0.0287758 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0287362 |
| LAMB1 | laminin, beta 1 | -0.0278538 |
| COL5A2 | collagen, type V, alpha 2 | -0.0269098 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0267491 |
| PKM | pyruvate kinase, muscle | -0.0266688 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0265015 |
| PXDN | peroxidasin | -0.0263735 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0262275 |
| RPS6 | ribosomal protein S6 | -0.0260259 |
| TPI1 | triosephosphate isomerase 1 | -0.0257624 |
| PTMA | prothymosin, alpha | -0.0256749 |
| NAV3 | neuron navigator 3 | -0.0251166 |
| AOPEP | aminopeptidase O (putative) | -0.0250383 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0247461 |
| SEPTIN7 | septin 7 | -0.024483 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0243369 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | -0.0240357 |
| MYO10 | myosin X | -0.0239417 |
| CA9 | carbonic anhydrase IX | -0.0238528 |
| ACTN4 | actinin, alpha 4 | -0.0236893 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0234727 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0232058 |
| AHR | aryl hydrocarbon receptor | -0.0231177 |
| ACTG1 | actin gamma 1 | -0.0230503 |
| KPNB1 | karyopherin (importin) beta 1 | -0.022211 |
| CD99 | CD99 molecule | -0.0221722 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0221488 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | -0.0220689 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0219641 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0218274 |
| PGK1 | phosphoglycerate kinase 1 | -0.0217874 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0216541 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.021455 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0213173 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0211909 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0209848 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0207542 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0204481 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0204119 |
| CENPE | centromere protein E, 312kDa | -0.0196896 |
| KIF4A | kinesin family member 4A | -0.0196773 |
| RPL35A | ribosomal protein L35a | -0.0195095 |
| H3-3B | H3.3 histone B | -0.0194015 |
| TUBA1B | tubulin, alpha 1b | -0.019361 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0192582 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0192182 |
| SMIM44 | small integral membrane protein 44 | -0.0191605 |
| RNF216 | ring finger protein 216 | -0.0191292 |
| PCDH7 | protocadherin 7 | -0.0188631 |
| VEGFC | vascular endothelial growth factor C | -0.0186393 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0185902 |
