| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.296798 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.127974 |
| FN1 | fibronectin 1 | 0.113549 |
| CDH13 | cadherin 13 | 0.105658 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0835639 |
| NDRG1 | N-myc downstream regulated 1 | 0.082528 |
| CADM1 | cell adhesion molecule 1 | 0.0775238 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0648977 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.060434 |
| VEGFA | vascular endothelial growth factor A | 0.0594096 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0503009 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0498809 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0493807 |
| PLEC | plectin | 0.0425647 |
| IER3 | immediate early response 3 | 0.0417169 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0414244 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0413878 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0397838 |
| RPS6 | ribosomal protein S6 | 0.0379166 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0375701 |
| GOLGA4 | golgin A4 | 0.034929 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0349028 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316305 |
| STC2 | stanniocalcin 2 | 0.0307196 |
| SQSTM1 | sequestosome 1 | 0.0302996 |
| RND3 | Rho family GTPase 3 | 0.0297079 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.026474 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0259697 |
| IRF1 | interferon regulatory factor 1 | 0.0257659 |
| COL5A1 | collagen, type V, alpha 1 | 0.0246448 |
| COL6A2 | collagen, type VI, alpha 2 | 0.024383 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0243321 |
| NAV2 | neuron navigator 2 | 0.0241492 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.023203 |
| GOLGB1 | golgin B1 | 0.0228015 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0225657 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0222683 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0222559 |
| FLNA | filamin A, alpha | 0.02211 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0215067 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209774 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0207851 |
| RPL13A | ribosomal protein L13a | 0.0205806 |
| MTDH | metadherin | 0.0205678 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.020494 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0202906 |
| HDAC9 | histone deacetylase 9 | 0.0202284 |
| RPL11 | ribosomal protein L11 | 0.0198061 |
| FMNL2 | formin-like 2 | 0.0191573 |
| FNIP1 | folliculin interacting protein 1 | 0.0186034 |
| MYO10 | myosin X | 0.0184075 |
| CALD1 | caldesmon 1 | 0.0183005 |
| ACTG1 | actin gamma 1 | 0.0182792 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0179558 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0179019 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0177821 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0174397 |
| ATF4 | activating transcription factor 4 | 0.0171137 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0171108 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0167843 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0167826 |
| RPS2 | ribosomal protein S2 | 0.0166249 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.016612 |
| EGFR | epidermal growth factor receptor | 0.0163551 |
| EFNA5 | ephrin-A5 | 0.0162649 |
| HYOU1 | hypoxia up-regulated 1 | 0.0160731 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0155243 |
| BRD2 | bromodomain containing 2 | 0.0155216 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0154947 |
| CMIP | c-Maf inducing protein | 0.0154104 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0153956 |
| EGR1 | early growth response 1 | 0.0152527 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0152452 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0151322 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0150586 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0147245 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0145869 |
| CUX1 | cut-like homeobox 1 | 0.0145237 |
| ADM | adrenomedullin | 0.014366 |
| HM13 | histocompatibility (minor) 13 | 0.0142738 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0141753 |
| ATXN1 | ataxin 1 | 0.0139681 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.013479 |
| RPS12 | ribosomal protein S12 | 0.0134731 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0134256 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0131079 |
| SESN2 | sestrin 2 | 0.0131025 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0130886 |
| CD109 | CD109 molecule | 0.0130057 |
| CLMP | CXADR-like membrane protein | 0.0129769 |
| SFTPA2 | surfactant protein A2 | 0.0129698 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0129253 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0129242 |
| FOXP1 | forkhead box P1 | 0.0128714 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0128466 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0128351 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0128343 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0128315 |
| RPL37A | ribosomal protein L37a | 0.0128265 |
| AAK1 | AP2 associated kinase 1 | 0.0127819 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167376 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147517 |
| COL1A1 | collagen, type I, alpha 1 | -0.113719 |
| MT2A | metallothionein 2A | -0.0949645 |
| VIM | vimentin | -0.082449 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0796496 |
| CD44 | CD44 molecule (Indian blood group) | -0.0775338 |
| UBC | ubiquitin C | -0.0771536 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0587248 |
| ENO1 | enolase 1, (alpha) | -0.0573938 |
| LDHA | lactate dehydrogenase A | -0.0486125 |
| MT1X | metallothionein 1X | -0.0456304 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0441575 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0409092 |
| TMSB10 | thymosin beta 10 | -0.0408437 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0403573 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360205 |
| STC1 | stanniocalcin 1 | -0.0320196 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0287201 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0273053 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0268875 |
| PTMA | prothymosin, alpha | -0.0251688 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0251339 |
| CALU | calumenin | -0.0238219 |
| PKM | pyruvate kinase, muscle | -0.0237568 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0236023 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0228371 |
| RPS27A | ribosomal protein S27a | -0.0219485 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0216369 |
| ARRDC3 | arrestin domain containing 3 | -0.0216002 |
| CANX | calnexin | -0.0206298 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0204998 |
| CLIC4 | chloride intracellular channel 4 | -0.0198092 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0196662 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0189928 |
| ASPH | aspartate beta-hydroxylase | -0.0183967 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0175424 |
| B2M | beta-2-microglobulin | -0.0175422 |
| RIGI | RNA sensor RIG-I | -0.0174508 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0173083 |
| SMAD3 | SMAD family member 3 | -0.0171321 |
| HMGA2 | high mobility group AT-hook 2 | -0.0168758 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0168625 |
| JUN | jun proto-oncogene | -0.0166871 |
| HAS2 | hyaluronan synthase 2 | -0.0161341 |
| RPL23 | ribosomal protein L23 | -0.0159252 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0159027 |
| PCBP2 | poly(rC) binding protein 2 | -0.015838 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0157894 |
| INHBA | inhibin, beta A | -0.0153872 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.015158 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0150702 |
| MX2 | MX dynamin-like GTPase 2 | -0.0144337 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0143004 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.014135 |
| ZNF292 | zinc finger protein 292 | -0.0139302 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0136738 |
| ECE1 | endothelin converting enzyme 1 | -0.0129825 |
| JAK2 | Janus kinase 2 | -0.0128227 |
| DUSP6 | dual specificity phosphatase 6 | -0.0127738 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0125502 |
| COL1A2 | collagen, type I, alpha 2 | -0.01218 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0118168 |
| ICAM1 | intercellular adhesion molecule 1 | -0.011732 |
| ACTN4 | actinin, alpha 4 | -0.0115158 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0113889 |
| PGK1 | phosphoglycerate kinase 1 | -0.0113481 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0111643 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0111475 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0108002 |
| KIAA1217 | KIAA1217 | -0.0106401 |
| AHNAK | AHNAK nucleoprotein | -0.010546 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0104615 |
| TFG | TRK-fused gene | -0.0103323 |
| NRP1 | neuropilin 1 | -0.0102939 |
| ATL1 | atlastin GTPase 1 | -0.0100339 |
| HMGB2 | high mobility group box 2 | -0.00993295 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00990262 |
| CALR | calreticulin | -0.00983389 |
| ANXA2 | annexin A2 | -0.00982101 |
| CUL4B | cullin 4B | -0.00964039 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0095881 |
| SERINC3 | serine incorporator 3 | -0.00950552 |
| PRELID2 | PRELI domain containing 2 | -0.00949027 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00948567 |
| IFI44 | interferon-induced protein 44 | -0.00944427 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.00944388 |
| OSMR | oncostatin M receptor | -0.00932163 |
| S100A10 | S100 calcium binding protein A10 | -0.00908777 |
| SEPTIN7 | septin 7 | -0.00906148 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00902299 |
| RHEB | Ras homolog enriched in brain | -0.00900141 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00894338 |
| CD82 | CD82 molecule | -0.00892041 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.00883568 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.00875405 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00872435 |
| TAGLN2 | transgelin 2 | -0.00871826 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00870813 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.00867279 |
