| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.213617 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.121217 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.113046 |
| FTL | ferritin, light polypeptide | 0.111825 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0941164 |
| SQSTM1 | sequestosome 1 | 0.0884636 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0714207 |
| H1-0 | H1.0 linker histone | 0.0707955 |
| TMEM65 | transmembrane protein 65 | 0.0589047 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0587535 |
| USP3 | ubiquitin specific peptidase 3 | 0.0578229 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0557653 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0547765 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0515573 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0490814 |
| EREG | epiregulin | 0.0488189 |
| PDS5B | PDS5 cohesin associated factor B | 0.0486551 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0479754 |
| PTMA | prothymosin, alpha | 0.0462081 |
| KRT18 | keratin 18, type I | 0.0447926 |
| MKI67 | marker of proliferation Ki-67 | 0.0422651 |
| SQLE | squalene epoxidase | 0.0418016 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0415672 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0402695 |
| NCKAP1 | NCK-associated protein 1 | 0.039943 |
| RNF145 | ring finger protein 145 | 0.0394918 |
| IPO7 | importin 7 | 0.0393426 |
| TOP1 | topoisomerase (DNA) I | 0.0380272 |
| TSC22D2 | TSC22 domain family, member 2 | 0.037611 |
| TXNRD1 | thioredoxin reductase 1 | 0.0375477 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0363773 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0362521 |
| YBX1 | Y box binding protein 1 | 0.0355356 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353682 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0347992 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.034549 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0342044 |
| SPAG9 | sperm associated antigen 9 | 0.0337593 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0332577 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332363 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0328733 |
| XPO1 | exportin 1 | 0.032473 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0318816 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0317517 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0317095 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0300403 |
| HMGB1 | high mobility group box 1 | 0.0287488 |
| KRT8 | keratin 8, type II | 0.0286982 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0283052 |
| LYZ | lysozyme | 0.0281268 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0268992 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0264518 |
| PTK2 | protein tyrosine kinase 2 | 0.0261275 |
| ECT2 | epithelial cell transforming 2 | 0.0259914 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0255261 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0253612 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0250004 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0246203 |
| WDR43 | WD repeat domain 43 | 0.024595 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0239669 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0239546 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0234784 |
| MATR3 | matrin 3 | 0.0232833 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0231989 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.023164 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0231321 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0228688 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0227064 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0225846 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0225822 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0225047 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0223931 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223567 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0223432 |
| TKT | transketolase | 0.022316 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0218502 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0218305 |
| NUP153 | nucleoporin 153kDa | 0.0217015 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.021586 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0213764 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0212321 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0212144 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0211986 |
| NOP58 | NOP58 ribonucleoprotein | 0.0211915 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.021101 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0210633 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0208342 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0205762 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0205082 |
| FNIP1 | folliculin interacting protein 1 | 0.0204787 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0203262 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0202813 |
| HDGF | hepatoma-derived growth factor | 0.0202793 |
| NFIA | nuclear factor I/A | 0.0202741 |
| TPX2 | TPX2, microtubule-associated | 0.0202153 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0201324 |
| FDPS | farnesyl diphosphate synthase | 0.0199682 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0199638 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0199635 |
| HMGB2 | high mobility group box 2 | 0.0198696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.207592 |
| LMO7 | LIM domain 7 | -0.0918196 |
| EZR | ezrin | -0.0860572 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0823365 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0815365 |
| ACTN4 | actinin, alpha 4 | -0.0813416 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0749364 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0664919 |
| FRY | furry homolog (Drosophila) | -0.0648368 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0636063 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0614533 |
| VCL | vinculin | -0.0608698 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0596978 |
| MYO1E | myosin IE | -0.0581411 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0578608 |
| LDHA | lactate dehydrogenase A | -0.0554533 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0546908 |
| STK24 | serine/threonine kinase 24 | -0.0541678 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0538018 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0533017 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0530935 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0506153 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0488017 |
| PGK1 | phosphoglycerate kinase 1 | -0.0478471 |
| GOLGB1 | golgin B1 | -0.0471034 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0466966 |
| BCL2L1 | BCL2-like 1 | -0.0465497 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0456471 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0455668 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0450555 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0442803 |
| PRELID2 | PRELI domain containing 2 | -0.0429082 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0428031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0427138 |
| TJP1 | tight junction protein 1 | -0.0422505 |
| KRT20 | keratin 20, type I | -0.0407422 |
| BPTF | bromodomain PHD finger transcription factor | -0.0403378 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0401682 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0400068 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0399702 |
| ETV6 | ets variant 6 | -0.0396774 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0392529 |
| ATXN1 | ataxin 1 | -0.0381367 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0377394 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0375867 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0375467 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366587 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0360409 |
| SMAD3 | SMAD family member 3 | -0.0356976 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.035288 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0347509 |
| PDZD8 | PDZ domain containing 8 | -0.0344149 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.034195 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0341931 |
| EGR1 | early growth response 1 | -0.0341132 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0337363 |
| WWC1 | WW and C2 domain containing 1 | -0.0332365 |
| TRIB1 | tribbles pseudokinase 1 | -0.0331997 |
| ZNF292 | zinc finger protein 292 | -0.0331992 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0330346 |
| ANXA11 | annexin A11 | -0.0328115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0324636 |
| VMP1 | vacuole membrane protein 1 | -0.0318926 |
| FHL2 | four and a half LIM domains 2 | -0.0317136 |
| ASPH | aspartate beta-hydroxylase | -0.0316151 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0311617 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0311597 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0311172 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0308893 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.03051 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0303499 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0303243 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0300651 |
| RNF213 | ring finger protein 213 | -0.0292481 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0287332 |
| LIMA1 | LIM domain and actin binding 1 | -0.0284145 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0280977 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0278846 |
| HM13 | histocompatibility (minor) 13 | -0.027785 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0277442 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0276246 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0275409 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0274955 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0274886 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0273984 |
| TMC5 | transmembrane channel-like 5 | -0.0269564 |
| UTRN | utrophin | -0.0267922 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0267805 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0262967 |
| RRBP1 | ribosome binding protein 1 | -0.0261129 |
| MUC13 | mucin 13, cell surface associated | -0.0261034 |
| AHNAK | AHNAK nucleoprotein | -0.0259427 |
| EXOC4 | exocyst complex component 4 | -0.025662 |
| TUFT1 | tuftelin 1 | -0.0250248 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0248894 |
| JUP | junction plakoglobin | -0.0247162 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0245118 |
| MCL1 | myeloid cell leukemia 1 | -0.0238548 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0237647 |
| TPM4 | tropomyosin 4 | -0.0235218 |
