| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | 0.143202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.091316 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0911387 |
| NPSR1 | neuropeptide S receptor 1 | 0.0904774 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0849411 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0738692 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0689057 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0683853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0669644 |
| PLEC | plectin | 0.0666471 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0664209 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0658441 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0651805 |
| EMP1 | epithelial membrane protein 1 | 0.0635965 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0623104 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0586913 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0585502 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0576062 |
| ATXN1 | ataxin 1 | 0.0563085 |
| EZR | ezrin | 0.056173 |
| KLHL29 | kelch-like family member 29 | 0.055857 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0554276 |
| SQSTM1 | sequestosome 1 | 0.0552728 |
| FLNB | filamin B, beta | 0.0523781 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0519855 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0510201 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0500363 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0472196 |
| PDLIM5 | PDZ and LIM domain 5 | 0.045722 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0455042 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0435789 |
| INTS6 | integrator complex subunit 6 | 0.0424682 |
| KRT8 | keratin 8, type II | 0.0424058 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0419828 |
| ANXA2 | annexin A2 | 0.0408214 |
| CDK6 | cyclin-dependent kinase 6 | 0.0407066 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0401447 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0399167 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0396819 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0392055 |
| EHBP1 | EH domain binding protein 1 | 0.0389346 |
| VCL | vinculin | 0.0386605 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0385302 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0380719 |
| LCN2 | lipocalin 2 | 0.0379688 |
| KRT18 | keratin 18, type I | 0.0372809 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0371657 |
| ITGA6 | integrin, alpha 6 | 0.036944 |
| AHR | aryl hydrocarbon receptor | 0.0361149 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0360902 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0356921 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0354605 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0353523 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0353343 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0347848 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0343832 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0343048 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0340769 |
| VMP1 | vacuole membrane protein 1 | 0.0339405 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0336556 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335614 |
| ANXA1 | annexin A1 | 0.0331647 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0331202 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0327714 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0324908 |
| SLMAP | sarcolemma associated protein | 0.0324587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320739 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0320539 |
| RUNX1 | runt-related transcription factor 1 | 0.0319129 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0318823 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0317707 |
| POF1B | premature ovarian failure, 1B | 0.0311944 |
| FBXO11 | F-box protein 11 | 0.0311034 |
| DENND1A | DENN/MADD domain containing 1A | 0.0310953 |
| TJP1 | tight junction protein 1 | 0.0310825 |
| AREG | amphiregulin | 0.0310405 |
| FNIP1 | folliculin interacting protein 1 | 0.0309339 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0302725 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.030257 |
| DSPP | dentin sialophosphoprotein | 0.0298767 |
| RPS12 | ribosomal protein S12 | 0.0298715 |
| AHNAK | AHNAK nucleoprotein | 0.0298535 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0297389 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0292483 |
| FOXO3 | forkhead box O3 | 0.0292357 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0291543 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0286947 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0286843 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0284799 |
| ANXA3 | annexin A3 | 0.0284166 |
| COBL | cordon-bleu WH2 repeat protein | 0.0283949 |
| CCNL1 | cyclin L1 | 0.0283079 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0280831 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0280429 |
| ASPH | aspartate beta-hydroxylase | 0.0278238 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0273579 |
| AFDN | afadin, adherens junction formation factor | 0.0272002 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0266507 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0262803 |
| DSTN | destrin (actin depolymerizing factor) | 0.0260367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.193039 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.157735 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.104732 |
| TMC5 | transmembrane channel-like 5 | -0.0622416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0550494 |
| AGR2 | anterior gradient 2 | -0.054395 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0535384 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0431703 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0398526 |
| B2M | beta-2-microglobulin | -0.0364572 |
| RRBP1 | ribosome binding protein 1 | -0.0362985 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0337371 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321794 |
| PRSS3 | protease, serine, 3 | -0.0310977 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.028993 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0284325 |
| WDR45B | WD repeat domain 45B | -0.0282746 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0278395 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0261819 |
| S100A9 | S100 calcium binding protein A9 | -0.0238985 |
| SELENOK | selenoprotein K | -0.0232387 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0230847 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0228358 |
| S100A11 | S100 calcium binding protein A11 | -0.0218685 |
| MUC17 | mucin 17, cell surface associated | -0.0218599 |
| FTL | ferritin, light polypeptide | -0.0215197 |
| PGK1 | phosphoglycerate kinase 1 | -0.0213193 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0212034 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0209547 |
| TXNIP | thioredoxin interacting protein | -0.0205946 |
| BPTF | bromodomain PHD finger transcription factor | -0.0201104 |
| TRAM1 | translocation associated membrane protein 1 | -0.0198498 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0193047 |
| MUC13 | mucin 13, cell surface associated | -0.0190785 |
| S100A10 | S100 calcium binding protein A10 | -0.0187809 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0187546 |
| UBE4A | ubiquitination factor E4A | -0.0185419 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0180594 |
| TMEM45B | transmembrane protein 45B | -0.0174771 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0171524 |
| ATM | ATM serine/threonine kinase | -0.0170667 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0166722 |
| SSR1 | signal sequence receptor, alpha | -0.0165193 |
| MGAM2 | maltase-glucoamylase 2 (putative) | -0.0163864 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0162655 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0162327 |
| RPL35A | ribosomal protein L35a | -0.0160139 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0157667 |
| SERINC3 | serine incorporator 3 | -0.0155577 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.015556 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0154378 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0153578 |
| UFL1 | UFM1-specific ligase 1 | -0.0153421 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0153323 |
| CLINT1 | clathrin interactor 1 | -0.0152378 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0150566 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0150145 |
| CD2AP | CD2-associated protein | -0.0147677 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0147325 |
| SMIM14 | small integral membrane protein 14 | -0.0146912 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.0146789 |
| ZNF652 | zinc finger protein 652 | -0.014578 |
| ASTN2 | astrotactin 2 | -0.014358 |
| TFF2 | trefoil factor 2 | -0.0143096 |
| PLS1 | plastin 1 | -0.0142757 |
| SRBD1 | S1 RNA binding domain 1 | -0.014015 |
| CST3 | cystatin C | -0.0138696 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0138058 |
| HMGB1 | high mobility group box 1 | -0.0137679 |
| CLDN7 | claudin 7 | -0.0137325 |
| HYOU1 | hypoxia up-regulated 1 | -0.0134921 |
| AGR3 | anterior gradient 3 | -0.0134296 |
| HDLBP | high density lipoprotein binding protein | -0.0132766 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0132322 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.013166 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0131579 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0129182 |
| SELENOS | selenoprotein S | -0.0129081 |
| COG6 | component of oligomeric golgi complex 6 | -0.0128521 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0127323 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0126626 |
| NUCB2 | nucleobindin 2 | -0.012623 |
| ARCN1 | archain 1 | -0.0126167 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0125938 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.01254 |
| FOXP1 | forkhead box P1 | -0.0124786 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0124687 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0124565 |
| TMSB10 | thymosin beta 10 | -0.0124244 |
| S100A6 | S100 calcium binding protein A6 | -0.0124191 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0123974 |
| MTDH | metadherin | -0.0123912 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.01233 |
| TUT7 | terminal uridylyl transferase 7 | -0.0122618 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.0121637 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0121179 |
| RPL8 | ribosomal protein L8 | -0.0117988 |
| CUL5 | cullin 5 | -0.0117169 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0116375 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0116335 |
