| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.147805 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0876959 |
| LSAMP | limbic system-associated membrane protein | 0.0829562 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0468877 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0428201 |
| FLNA | filamin A, alpha | 0.0407717 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0372218 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0352786 |
| RPL21 | ribosomal protein L21 | 0.0305901 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0278623 |
| PRKCE | protein kinase C, epsilon | 0.0266959 |
| CD109 | CD109 molecule | 0.0266055 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0261201 |
| RPL13A | ribosomal protein L13a | 0.0251084 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0240143 |
| PLEC | plectin | 0.023777 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.022588 |
| GOLGA4 | golgin A4 | 0.0221832 |
| ADM | adrenomedullin | 0.0219416 |
| RPS12 | ribosomal protein S12 | 0.0218501 |
| HDAC9 | histone deacetylase 9 | 0.0214987 |
| RNF145 | ring finger protein 145 | 0.019592 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0192761 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0185267 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0178567 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0173021 |
| WDR45B | WD repeat domain 45B | 0.0170545 |
| MSI2 | musashi RNA-binding protein 2 | 0.0164492 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0163443 |
| FLNC | filamin C, gamma | 0.0162531 |
| HELZ | helicase with zinc finger | 0.0162037 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0159508 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0157809 |
| TEX14 | testis expressed 14 | 0.0157676 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0155369 |
| NUP58 | nucleoporin 58 | 0.0152473 |
| TPM2 | tropomyosin 2 (beta) | 0.0151376 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0149773 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0147948 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0144125 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0143177 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0139202 |
| RPS17 | ribosomal protein S17 | 0.0137906 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0134594 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0134463 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0133981 |
| USP36 | ubiquitin specific peptidase 36 | 0.0132979 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0131448 |
| EFNA5 | ephrin-A5 | 0.0131444 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0129757 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0128503 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0126413 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0126114 |
| FBXO42 | F-box protein 42 | 0.0125063 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0124534 |
| TFRC | transferrin receptor | 0.0123912 |
| RPL37A | ribosomal protein L37a | 0.0122598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0121556 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0120628 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0119826 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0118095 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0115281 |
| COPA | coatomer protein complex, subunit alpha | 0.0115222 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0115092 |
| USP3 | ubiquitin specific peptidase 3 | 0.0115052 |
| ARF4 | ADP-ribosylation factor 4 | 0.011302 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0112418 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.01123 |
| INTS6 | integrator complex subunit 6 | 0.0111871 |
| FOXO3 | forkhead box O3 | 0.011171 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0111635 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0110228 |
| HDAC3 | histone deacetylase 3 | 0.0109947 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0109367 |
| YBX1 | Y box binding protein 1 | 0.0108277 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0108074 |
| H1-0 | H1.0 linker histone | 0.0107671 |
| YTHDC1 | YTH domain containing 1 | 0.0107625 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0106995 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0106425 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0106103 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0105941 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0105879 |
| DHFR | dihydrofolate reductase | 0.0105076 |
| ATF3 | activating transcription factor 3 | 0.010486 |
| FNIP1 | folliculin interacting protein 1 | 0.0103466 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0102042 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0101198 |
| RBM33 | RNA binding motif protein 33 | 0.0100646 |
| RPL11 | ribosomal protein L11 | 0.00999757 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00985549 |
| CTBP2 | C-terminal binding protein 2 | 0.00982813 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00975244 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0097456 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00966689 |
| FBL | fibrillarin | 0.00964197 |
| SAFB2 | scaffold attachment factor B2 | 0.00956256 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.00942633 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.00927247 |
| FAM193A | family with sequence similarity 193, member A | 0.00910854 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.178146 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.153207 |
| VCL | vinculin | -0.0879453 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0850645 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.077586 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0759978 |
| AHNAK | AHNAK nucleoprotein | -0.0752103 |
| ASPH | aspartate beta-hydroxylase | -0.0689436 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0689027 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0688452 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0645293 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0613446 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0607256 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0598475 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0595116 |
| CD44 | CD44 molecule (Indian blood group) | -0.0590503 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0525336 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0516511 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0510525 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0506733 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0494518 |
| KIAA1549L | KIAA1549-like | -0.0492168 |
| RTN4 | reticulon 4 | -0.0473737 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.04731 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0466838 |
| LDHA | lactate dehydrogenase A | -0.0465803 |
| TXNRD1 | thioredoxin reductase 1 | -0.0454455 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0447341 |
| CDK17 | cyclin-dependent kinase 17 | -0.0442673 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0438907 |
| KIAA1217 | KIAA1217 | -0.0435882 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0434656 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0425032 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0419756 |
| CDK6 | cyclin-dependent kinase 6 | -0.0417566 |
| TPM4 | tropomyosin 4 | -0.0417231 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0415819 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0408166 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0392069 |
| FRMD6 | FERM domain containing 6 | -0.0380769 |
| FOXP1 | forkhead box P1 | -0.0377404 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0375157 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0373201 |
| CTSB | cathepsin B | -0.0364908 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0362599 |
| ANO6 | anoctamin 6 | -0.0356902 |
| HMGA2 | high mobility group AT-hook 2 | -0.0356639 |
| CAVIN1 | caveolae associated protein 1 | -0.0355546 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0350406 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0348372 |
| STC1 | stanniocalcin 1 | -0.0345327 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0344768 |
| NTM | neurotrimin | -0.0334577 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0332229 |
| CALD1 | caldesmon 1 | -0.0330189 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0329003 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0327139 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0326917 |
| PTMA | prothymosin, alpha | -0.0323277 |
| GPC6 | glypican 6 | -0.0321101 |
| TXNIP | thioredoxin interacting protein | -0.0315008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0310733 |
| RAI14 | retinoic acid induced 14 | -0.0310631 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0309444 |
| KYNU | kynureninase | -0.0309082 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0307036 |
| TNNC1 | troponin C type 1 (slow) | -0.0303183 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0297773 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0296728 |
| ITGA6 | integrin, alpha 6 | -0.0291726 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0289329 |
| NAV1 | neuron navigator 1 | -0.0288888 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0287111 |
| MAP1B | microtubule-associated protein 1B | -0.0284064 |
| PGK1 | phosphoglycerate kinase 1 | -0.0282083 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0279404 |
| MMP12 | matrix metallopeptidase 12 | -0.0275796 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0275165 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0273258 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273023 |
| YBX3 | Y box binding protein 3 | -0.0272506 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271914 |
| BPTF | bromodomain PHD finger transcription factor | -0.0270735 |
| EMP1 | epithelial membrane protein 1 | -0.0269658 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0267842 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0264919 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.02632 |
| JMJD1C | jumonji domain containing 1C | -0.0258971 |
| RIGI | RNA sensor RIG-I | -0.0258831 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0256913 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0250843 |
| OSMR | oncostatin M receptor | -0.0247976 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0242395 |
| ETV6 | ets variant 6 | -0.0242369 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0241154 |
| MAP4 | microtubule-associated protein 4 | -0.0240142 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0240061 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0239637 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0238074 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0237115 |
