| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.228461 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.207904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.18614 |
| KRT18 | keratin 18, type I | 0.126752 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.11854 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109619 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0797777 |
| CALR | calreticulin | 0.0747697 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0745998 |
| GOLGA4 | golgin A4 | 0.0744041 |
| RPL13A | ribosomal protein L13a | 0.0713495 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0711497 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0699098 |
| RPS12 | ribosomal protein S12 | 0.0592152 |
| NDRG1 | N-myc downstream regulated 1 | 0.0558168 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0551096 |
| H1-0 | H1.0 linker histone | 0.0533746 |
| EREG | epiregulin | 0.0532542 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0524916 |
| FAM13A | family with sequence similarity 13, member A | 0.0524809 |
| KRT8 | keratin 8, type II | 0.050417 |
| AHNAK | AHNAK nucleoprotein | 0.0498658 |
| S100P | S100 calcium binding protein P | 0.0482386 |
| OGA | O-GlcNAcase | 0.0460373 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0458918 |
| RBM39 | RNA binding motif protein 39 | 0.0436082 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0435731 |
| CANX | calnexin | 0.0435679 |
| RNF145 | ring finger protein 145 | 0.0433797 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0432364 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0426615 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0425938 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0423062 |
| RPS2 | ribosomal protein S2 | 0.041159 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0402824 |
| RPL12 | ribosomal protein L12 | 0.0400794 |
| PLEC | plectin | 0.0400737 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0380412 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0378811 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0378277 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0366827 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036051 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0360188 |
| DSPP | dentin sialophosphoprotein | 0.0358656 |
| RPL37A | ribosomal protein L37a | 0.035843 |
| RPL21 | ribosomal protein L21 | 0.0357361 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0349473 |
| HDLBP | high density lipoprotein binding protein | 0.0342613 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0338971 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0337893 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.033086 |
| TXNIP | thioredoxin interacting protein | 0.0327604 |
| EZR | ezrin | 0.0325915 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0325499 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0323144 |
| RPL11 | ribosomal protein L11 | 0.0321802 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0321003 |
| RPL26 | ribosomal protein L26 | 0.0320782 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0313902 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0312308 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0311446 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0309036 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0308542 |
| MED13L | mediator complex subunit 13-like | 0.0302535 |
| GDF15 | growth differentiation factor 15 | 0.0300242 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0299661 |
| COPA | coatomer protein complex, subunit alpha | 0.029877 |
| YBX1 | Y box binding protein 1 | 0.0297667 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0289678 |
| RPS3 | ribosomal protein S3 | 0.0289278 |
| VEGFA | vascular endothelial growth factor A | 0.0289167 |
| LMO7 | LIM domain 7 | 0.0287823 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0285444 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0282062 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0280087 |
| COG5 | component of oligomeric golgi complex 5 | 0.0278988 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0278773 |
| NCKAP1 | NCK-associated protein 1 | 0.0278091 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0276632 |
| RPS29 | ribosomal protein S29 | 0.0275293 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0271514 |
| RPLP2 | ribosomal protein, large, P2 | 0.0270383 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0267076 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.02667 |
| TMF1 | TATA element modulatory factor 1 | 0.0263855 |
| TXNRD1 | thioredoxin reductase 1 | 0.0263514 |
| ATXN1 | ataxin 1 | 0.0261484 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0260593 |
| HSPA8 | heat shock 70kDa protein 8 | 0.026032 |
| AFDN | afadin, adherens junction formation factor | 0.0257688 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0256818 |
| MYO5B | myosin VB | 0.0252758 |
| BRD2 | bromodomain containing 2 | 0.0252489 |
| RPL19 | ribosomal protein L19 | 0.0252351 |
| TMSB4X | thymosin beta 4, X-linked | 0.0251955 |
| KIF5B | kinesin family member 5B | 0.0251427 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.024562 |
| PAPOLA | poly(A) polymerase alpha | 0.0244227 |
| RPL36 | ribosomal protein L36 | 0.0244101 |
| SEC24D | SEC24 family member D | 0.0240693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.179973 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.177426 |
| TMSB10 | thymosin beta 10 | -0.118891 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0985735 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0979047 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0960251 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0816146 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0705493 |
| POTEF | POTE ankyrin domain family, member F | -0.0620476 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0606646 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0576589 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0567294 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0551508 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0526985 |
| MYO1E | myosin IE | -0.0520067 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0504945 |
| ACTG1 | actin gamma 1 | -0.0481427 |
| TFF1 | trefoil factor 1 | -0.0472458 |
| MUC17 | mucin 17, cell surface associated | -0.0466191 |
| CALB1 | calbindin 1, 28kDa | -0.0456516 |
| RPL35A | ribosomal protein L35a | -0.0445741 |
| PTMA | prothymosin, alpha | -0.0424714 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0423865 |
| KLK10 | kallikrein-related peptidase 10 | -0.0383439 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0383422 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0370871 |
| SH3D19 | SH3 domain containing 19 | -0.035738 |
| FHIT | fragile histidine triad | -0.0353209 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0351641 |
| ITGA6 | integrin, alpha 6 | -0.035074 |
| LAMA4 | laminin, alpha 4 | -0.0343008 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0340384 |
| HMGA1 | high mobility group AT-hook 1 | -0.0338959 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0326019 |
| VCL | vinculin | -0.0325963 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0317975 |
| TUBA1B | tubulin, alpha 1b | -0.0315229 |
| S100A6 | S100 calcium binding protein A6 | -0.0308474 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0300659 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0297494 |
| RNF217 | ring finger protein 217 | -0.0296431 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0296073 |
| SLC35F3 | solute carrier family 35, member F3 | -0.029185 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0289315 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0288332 |
| PRSS3 | protease, serine, 3 | -0.0283933 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.028183 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0279771 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0278925 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0276717 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0274956 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0270668 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0269799 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0264289 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0262722 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0262594 |
| FERMT1 | fermitin family member 1 | -0.0261759 |
| ACTN4 | actinin, alpha 4 | -0.0259269 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0258051 |
| LDHA | lactate dehydrogenase A | -0.0255613 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0252171 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0245767 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0245627 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0244639 |
| BMP4 | bone morphogenetic protein 4 | -0.0239468 |
| FOXP1 | forkhead box P1 | -0.023808 |
| TPM4 | tropomyosin 4 | -0.0235469 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0234709 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0233901 |
| DIAPH2 | diaphanous-related formin 2 | -0.0232264 |
| PFN1 | profilin 1 | -0.0228242 |
| CLOCK | clock circadian regulator | -0.0228071 |
| LSAMP | limbic system-associated membrane protein | -0.0227919 |
| RAD51B | RAD51 paralog B | -0.0216226 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0215184 |
| FRMD5 | FERM domain containing 5 | -0.0209966 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0209573 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0207477 |
| TNS4 | tensin 4 | -0.0206515 |
| GPHN | gephyrin | -0.0204254 |
| CBX3 | chromobox homolog 3 | -0.0203472 |
| TPI1 | triosephosphate isomerase 1 | -0.0203306 |
| MYO1D | myosin ID | -0.0201632 |
| PCDH9 | protocadherin 9 | -0.0201196 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0199871 |
| EPHB2 | EPH receptor B2 | -0.0195698 |
| RIN2 | Ras and Rab interactor 2 | -0.0194924 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0191964 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0189315 |
| DEK | DEK proto-oncogene | -0.0182916 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0182757 |
| RAB10 | RAB10, member RAS oncogene family | -0.0180293 |
| PRDX2 | peroxiredoxin 2 | -0.0179452 |
| PDLIM5 | PDZ and LIM domain 5 | -0.017856 |
| PERP | PERP, TP53 apoptosis effector | -0.0177883 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0177142 |
| SMYD3 | SET and MYND domain containing 3 | -0.0175328 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0174908 |
| DIAPH1 | diaphanous-related formin 1 | -0.0174062 |
| PKP2 | plakophilin 2 | -0.017277 |
