| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.181915 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.089734 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0841914 |
| GOLGA4 | golgin A4 | 0.0826574 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0727327 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0698252 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0663484 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0644997 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0612908 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0597476 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0555267 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0548455 |
| TXNRD1 | thioredoxin reductase 1 | 0.0548157 |
| RPL13A | ribosomal protein L13a | 0.0533436 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0516908 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0501376 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0496269 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0462524 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0462255 |
| EREG | epiregulin | 0.0445551 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.043787 |
| RNF145 | ring finger protein 145 | 0.0430324 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0421099 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0407494 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403209 |
| SQSTM1 | sequestosome 1 | 0.0393231 |
| RPS6 | ribosomal protein S6 | 0.038427 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.037718 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0372499 |
| BRD2 | bromodomain containing 2 | 0.0370251 |
| GDF15 | growth differentiation factor 15 | 0.0369979 |
| ATXN1 | ataxin 1 | 0.036332 |
| OGA | O-GlcNAcase | 0.0354864 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0354738 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0353028 |
| USP3 | ubiquitin specific peptidase 3 | 0.0351039 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0345681 |
| RPS12 | ribosomal protein S12 | 0.0339789 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337582 |
| RPL3 | ribosomal protein L3 | 0.0328444 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0327438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0322875 |
| CANX | calnexin | 0.0322398 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0321104 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0320974 |
| CCPG1 | cell cycle progression 1 | 0.0320628 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0317053 |
| NDRG1 | N-myc downstream regulated 1 | 0.03162 |
| MYO6 | myosin VI | 0.0315727 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0314731 |
| COPA | coatomer protein complex, subunit alpha | 0.0314061 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0310755 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0310643 |
| RPS2 | ribosomal protein S2 | 0.0310301 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0306797 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0295763 |
| XPOT | exportin, tRNA | 0.0288563 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0287962 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0284234 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0279666 |
| HDLBP | high density lipoprotein binding protein | 0.0273315 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0272461 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.027164 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0271531 |
| AREG | amphiregulin | 0.0268436 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0266454 |
| SRP54 | signal recognition particle 54kDa | 0.0263193 |
| SUCO | SUN domain containing ossification factor | 0.0259521 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0259285 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0257288 |
| RPL21 | ribosomal protein L21 | 0.0256915 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0253567 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0252524 |
| TMF1 | TATA element modulatory factor 1 | 0.0251229 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0251194 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025089 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0243731 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0239883 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0239506 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0235999 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0232373 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0231165 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0230078 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0228831 |
| NKTR | natural killer cell triggering receptor | 0.0228797 |
| MED13L | mediator complex subunit 13-like | 0.0226141 |
| SEC24D | SEC24 family member D | 0.0223422 |
| SPAG9 | sperm associated antigen 9 | 0.0220043 |
| TMEM41B | transmembrane protein 41B | 0.0217501 |
| CALU | calumenin | 0.0216795 |
| ATF4 | activating transcription factor 4 | 0.0216111 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0213584 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0213065 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0212757 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0210813 |
| SEC24A | SEC24 family member A | 0.0210565 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0208296 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0208172 |
| MORF4L2 | mortality factor 4 like 2 | 0.0207571 |
| PTEN | phosphatase and tensin homolog | 0.0207253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | -0.134123 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.111907 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0900858 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0875393 |
| MYO1E | myosin IE | -0.0853265 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0696822 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0676365 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0653514 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0628233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0620279 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0566573 |
| MX1 | MX dynamin-like GTPase 1 | -0.0551878 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0530503 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.050447 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0496494 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0495958 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0487262 |
| FRMD5 | FERM domain containing 5 | -0.0481769 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.048167 |
| RIGI | RNA sensor RIG-I | -0.047932 |
| MSI2 | musashi RNA-binding protein 2 | -0.0479138 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.045941 |
| SP100 | SP100 nuclear antigen | -0.0445706 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0444159 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0440001 |
| TSPAN8 | tetraspanin 8 | -0.0431116 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0409288 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0409198 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0408323 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0405109 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387262 |
| FOXP1 | forkhead box P1 | -0.0386538 |
| AOPEP | aminopeptidase O (putative) | -0.0371343 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0368556 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0364428 |
| VCL | vinculin | -0.0359763 |
| PRSS3 | protease, serine, 3 | -0.0359737 |
| FERMT1 | fermitin family member 1 | -0.0349408 |
| RNF213 | ring finger protein 213 | -0.0344591 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0340609 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.033945 |
| MUC13 | mucin 13, cell surface associated | -0.0329678 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.032577 |
| PALLD | palladin, cytoskeletal associated protein | -0.032481 |
| CLIC5 | chloride intracellular channel 5 | -0.0317222 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0316893 |
| ABHD17C | abhydrolase domain containing 17C | -0.0316258 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0315732 |
| PERP | PERP, TP53 apoptosis effector | -0.0313917 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0312579 |
| LAMA4 | laminin, alpha 4 | -0.0304323 |
| PLSCR1 | phospholipid scramblase 1 | -0.029944 |
| LMO7 | LIM domain 7 | -0.0298144 |
| NPSR1 | neuropeptide S receptor 1 | -0.0296606 |
| XAF1 | XIAP associated factor 1 | -0.0290584 |
| DSG3 | desmoglein 3 | -0.0284966 |
| FHIT | fragile histidine triad | -0.0283539 |
| MX2 | MX dynamin-like GTPase 2 | -0.0282366 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0281369 |
| ACTN4 | actinin, alpha 4 | -0.0273059 |
| ANXA11 | annexin A11 | -0.0272333 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0270458 |
| PKP2 | plakophilin 2 | -0.0269512 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0267387 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0266426 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0263774 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0259656 |
| ATP10B | ATPase, class V, type 10B | -0.0259286 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0258947 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.025754 |
| COBL | cordon-bleu WH2 repeat protein | -0.0254187 |
| SERINC5 | serine incorporator 5 | -0.0252495 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | -0.0251574 |
| DIAPH1 | diaphanous-related formin 1 | -0.0251449 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0250881 |
| DIAPH2 | diaphanous-related formin 2 | -0.0250294 |
| POTEF | POTE ankyrin domain family, member F | -0.0249948 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0249306 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0248963 |
| RAD51B | RAD51 paralog B | -0.0247029 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0246962 |
| DSG2 | desmoglein 2 | -0.0245138 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0244178 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.024277 |
| CUX1 | cut-like homeobox 1 | -0.0240539 |
| SVIL | supervillin | -0.0236631 |
| MCU | mitochondrial calcium uniporter | -0.0236015 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0235398 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.023428 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.023149 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0231385 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0231348 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0231125 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0229303 |
| MTAP | methylthioadenosine phosphorylase | -0.0227819 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0226868 |
| SMYD3 | SET and MYND domain containing 3 | -0.0225346 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0223971 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0223609 |
| TPM1 | tropomyosin 1 (alpha) | -0.0223416 |
