| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.162172 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.107244 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.101239 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0994233 |
| PTMA | prothymosin, alpha | 0.0959349 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0941104 |
| TMSB4X | thymosin beta 4, X-linked | 0.0920268 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0883539 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.084957 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0836326 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0715545 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0704682 |
| LRRC49 | leucine rich repeat containing 49 | 0.0700212 |
| HLA-B | major histocompatibility complex, class I, B | 0.0686276 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0679566 |
| DST | dystonin | 0.0676032 |
| KLF6 | Kruppel-like factor 6 | 0.0644088 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0597663 |
| CADM2 | cell adhesion molecule 2 | 0.0584916 |
| EFNA5 | ephrin-A5 | 0.0557462 |
| AHNAK | AHNAK nucleoprotein | 0.0555359 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.050244 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.050221 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0501577 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0501172 |
| PLK2 | polo-like kinase 2 | 0.0490793 |
| EPHA4 | EPH receptor A4 | 0.0469072 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0465767 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0458116 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0455098 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0451957 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0450965 |
| TNS3 | tensin 3 | 0.0424825 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0423659 |
| ENO1 | enolase 1, (alpha) | 0.0409647 |
| KRT18 | keratin 18, type I | 0.0401332 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0386194 |
| TMEM123 | transmembrane protein 123 | 0.0383895 |
| ANXA2 | annexin A2 | 0.0378185 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0377564 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0370742 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0369904 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0365998 |
| H1-0 | H1.0 linker histone | 0.0362426 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0354756 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0354581 |
| HDLBP | high density lipoprotein binding protein | 0.0350872 |
| RNF213 | ring finger protein 213 | 0.0343246 |
| HDAC9 | histone deacetylase 9 | 0.0340401 |
| CD44 | CD44 molecule (Indian blood group) | 0.0328223 |
| SQSTM1 | sequestosome 1 | 0.0323499 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0322803 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0322018 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0315718 |
| CALR | calreticulin | 0.0313268 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.031056 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0306927 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0306863 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0301849 |
| FLNB | filamin B, beta | 0.0297226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0297046 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0296616 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.029541 |
| TUBB | tubulin, beta class I | 0.029508 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0293323 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029157 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.029111 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.02907 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0290497 |
| PLIN2 | perilipin 2 | 0.0289734 |
| MAP4 | microtubule-associated protein 4 | 0.0287567 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0281023 |
| SESN2 | sestrin 2 | 0.0280089 |
| APP | amyloid beta (A4) precursor protein | 0.0279147 |
| JUN | jun proto-oncogene | 0.0273245 |
| CRY1 | cryptochrome circadian clock 1 | 0.0270232 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.026924 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0267354 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0264956 |
| MYOF | myoferlin | 0.0260448 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0259662 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0255638 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0255302 |
| CUX1 | cut-like homeobox 1 | 0.0253016 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0252451 |
| EGFR | epidermal growth factor receptor | 0.0249845 |
| KPNB1 | karyopherin (importin) beta 1 | 0.024794 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0247584 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0246712 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0245753 |
| SFTPA2 | surfactant protein A2 | 0.024316 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0242865 |
| VEGFA | vascular endothelial growth factor A | 0.0239441 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0238769 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0238206 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0237904 |
| QKI | QKI, KH domain containing, RNA binding | 0.0235511 |
| PLEC | plectin | 0.0234774 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0233699 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.023319 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.211123 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173407 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.149379 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.141638 |
| TXNRD1 | thioredoxin reductase 1 | -0.107078 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.101147 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0966097 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0890026 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0874121 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.081337 |
| MT1X | metallothionein 1X | -0.0773611 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0729025 |
| USP34 | ubiquitin specific peptidase 34 | -0.0648974 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0612564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0583648 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0570131 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.055075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0545175 |
| MT1E | metallothionein 1E | -0.0544302 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0519923 |
| RAI1 | retinoic acid induced 1 | -0.0490334 |
| RPS2 | ribosomal protein S2 | -0.0487656 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0425317 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0423962 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0397518 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0375004 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0369681 |
| YBX3 | Y box binding protein 3 | -0.0369623 |
| ANGPTL4 | angiopoietin-like 4 | -0.0367646 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0366925 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0362012 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0357871 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0346296 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0344671 |
| PYGL | phosphorylase, glycogen, liver | -0.0341518 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0337239 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0334858 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0334522 |
| EMP1 | epithelial membrane protein 1 | -0.0329793 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0328631 |
| WDR26 | WD repeat domain 26 | -0.0322641 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0321721 |
| CEP170 | centrosomal protein 170kDa | -0.0315443 |
| CDCP1 | CUB domain containing protein 1 | -0.0311354 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0310337 |
| ZNF292 | zinc finger protein 292 | -0.0309167 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0296464 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0296304 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0294281 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.028987 |
| EZR | ezrin | -0.0289351 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0286898 |
| VMP1 | vacuole membrane protein 1 | -0.0270519 |
| RTN4 | reticulon 4 | -0.0270002 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0268571 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0266883 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0265913 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0265652 |
| SEC24A | SEC24 family member A | -0.0257127 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0256781 |
| PRDX1 | peroxiredoxin 1 | -0.0256521 |
| TMEM41B | transmembrane protein 41B | -0.0254033 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0252881 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.024939 |
| POM121 | POM121 transmembrane nucleoporin | -0.0243463 |
| RECQL | RecQ helicase-like | -0.0243232 |
| FERMT1 | fermitin family member 1 | -0.0239728 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0239332 |
| CAPRIN2 | caprin family member 2 | -0.0237525 |
| BARX2 | BARX homeobox 2 | -0.0234167 |
| S100A6 | S100 calcium binding protein A6 | -0.0231561 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0230658 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0230571 |
| CENPF | centromere protein F, 350/400kDa | -0.0230285 |
| DIAPH3 | diaphanous-related formin 3 | -0.0229976 |
| RRM2 | ribonucleotide reductase M2 | -0.0228321 |
| CMIP | c-Maf inducing protein | -0.0228158 |
| KIAA1958 | KIAA1958 | -0.0227709 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0227156 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0221281 |
| YEATS2 | YEATS domain containing 2 | -0.0217266 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0216041 |
| IL6ST | interleukin 6 signal transducer | -0.0215525 |
| USP12 | ubiquitin specific peptidase 12 | -0.0215203 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0214412 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0203365 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0197159 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0196831 |
| NEK7 | NIMA-related kinase 7 | -0.0195889 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0195775 |
| PCBP2 | poly(rC) binding protein 2 | -0.0195746 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0193617 |
| HPCAL1 | hippocalcin-like 1 | -0.0193061 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0192974 |
| EVI5 | ecotropic viral integration site 5 | -0.0192905 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0192783 |
| FOXJ3 | forkhead box J3 | -0.0192626 |
| MYO9B | myosin IXB | -0.0189345 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.0189314 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0188557 |
