| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.251647 |
| FN1 | fibronectin 1 | 0.198081 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0809216 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.072497 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0722903 |
| SQSTM1 | sequestosome 1 | 0.0679598 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0640234 |
| ANXA2 | annexin A2 | 0.0632308 |
| PLEC | plectin | 0.0629962 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0598145 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0589672 |
| LAMC2 | laminin, gamma 2 | 0.057046 |
| ASPH | aspartate beta-hydroxylase | 0.0569018 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0568909 |
| CCND1 | cyclin D1 | 0.0559806 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0559092 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0547458 |
| AHNAK | AHNAK nucleoprotein | 0.0518715 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0473732 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.046956 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0453028 |
| HMGB2 | high mobility group box 2 | 0.0448672 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442934 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0430324 |
| APP | amyloid beta (A4) precursor protein | 0.042093 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.04162 |
| RPL4 | ribosomal protein L4 | 0.040232 |
| TMSB4X | thymosin beta 4, X-linked | 0.0400558 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0393221 |
| KRT7 | keratin 7, type II | 0.0390254 |
| PLAU | plasminogen activator, urokinase | 0.0389836 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0387317 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0383887 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0380122 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0379418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0378361 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0372464 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.036427 |
| LMO7 | LIM domain 7 | 0.0363791 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0357688 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.035458 |
| TFRC | transferrin receptor | 0.0351812 |
| TXNRD1 | thioredoxin reductase 1 | 0.0340901 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0334439 |
| CANX | calnexin | 0.033317 |
| RLF | rearranged L-myc fusion | 0.0333044 |
| ZNF292 | zinc finger protein 292 | 0.0325974 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0325326 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0319322 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0311002 |
| PEG10 | paternally expressed 10 | 0.0310083 |
| SGMS2 | sphingomyelin synthase 2 | 0.0309746 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0308349 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0301486 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0301367 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0298011 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0297467 |
| RHEB | Ras homolog enriched in brain | 0.0296375 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0292945 |
| PAPOLA | poly(A) polymerase alpha | 0.0291702 |
| SPAG9 | sperm associated antigen 9 | 0.0291419 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0286715 |
| RPL14 | ribosomal protein L14 | 0.028595 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0284374 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0283411 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0283338 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0282442 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.028021 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0278492 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0277791 |
| CLINT1 | clathrin interactor 1 | 0.0277052 |
| WDR43 | WD repeat domain 43 | 0.0269843 |
| SDC4 | syndecan 4 | 0.0265095 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0263002 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0261763 |
| FLNA | filamin A, alpha | 0.0250573 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0249588 |
| SMAD3 | SMAD family member 3 | 0.0247518 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0245873 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0245762 |
| LAMB3 | laminin, beta 3 | 0.0244188 |
| HDLBP | high density lipoprotein binding protein | 0.0243357 |
| ANLN | anillin, actin binding protein | 0.024005 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0238886 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.023785 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0237748 |
| IRF6 | interferon regulatory factor 6 | 0.0235226 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0234337 |
| PTK2 | protein tyrosine kinase 2 | 0.0233635 |
| GNAS | GNAS complex locus | 0.0233068 |
| ARF1 | ADP-ribosylation factor 1 | 0.0232164 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0230717 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0229772 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.02295 |
| YBX3 | Y box binding protein 3 | 0.0226892 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.022497 |
| EPCAM | epithelial cell adhesion molecule | 0.0223344 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0222491 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0220944 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0220709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161932 |
| FTL | ferritin, light polypeptide | -0.144654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.115865 |
| NDRG1 | N-myc downstream regulated 1 | -0.113033 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0958045 |
| TMSB10 | thymosin beta 10 | -0.0872934 |
| MT2A | metallothionein 2A | -0.0724553 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0715543 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0672791 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0580457 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0558476 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0492662 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0447678 |
| POTEF | POTE ankyrin domain family, member F | -0.0445512 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0442492 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.04374 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0433586 |
| RPLP2 | ribosomal protein, large, P2 | -0.0408068 |
| RPS19 | ribosomal protein S19 | -0.0397189 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0396397 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0389616 |
| FBXO32 | F-box protein 32 | -0.0387695 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0372768 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358927 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0352766 |
| S100A9 | S100 calcium binding protein A9 | -0.0350955 |
| HMGA1 | high mobility group AT-hook 1 | -0.0350091 |
| RPS23 | ribosomal protein S23 | -0.0344198 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0329583 |
| G0S2 | G0/G1 switch 2 | -0.0319016 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0316201 |
| TXNIP | thioredoxin interacting protein | -0.0312001 |
| RPS12 | ribosomal protein S12 | -0.030851 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0304172 |
| TMEM165 | transmembrane protein 165 | -0.0302167 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0286472 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0285474 |
| CSTB | cystatin B (stefin B) | -0.0282039 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0279303 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0272065 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0266066 |
| FAM3C | family with sequence similarity 3, member C | -0.0262421 |
| MSN | moesin | -0.0262127 |
| HLA-A | major histocompatibility complex, class I, A | -0.0256298 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0255757 |
| IFI44L | interferon-induced protein 44-like | -0.0255709 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0253394 |
| CLDN4 | claudin 4 | -0.0251492 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0251414 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0251386 |
| RPS27 | ribosomal protein S27 | -0.0247622 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0245155 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0243456 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240197 |
| EFNA5 | ephrin-A5 | -0.0239129 |
| PCBP2 | poly(rC) binding protein 2 | -0.0233945 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0232493 |
| FOSL1 | FOS-like antigen 1 | -0.0229428 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0228932 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0228279 |
| VEGFA | vascular endothelial growth factor A | -0.0226946 |
| RPS17 | ribosomal protein S17 | -0.0222899 |
| RNF213 | ring finger protein 213 | -0.02228 |
| LDHA | lactate dehydrogenase A | -0.02215 |
| RPS25 | ribosomal protein S25 | -0.0217987 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0215771 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0213734 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0211804 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0210942 |
| RPL9 | ribosomal protein L9 | -0.0209693 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0207098 |
| ADAR | adenosine deaminase, RNA-specific | -0.0203027 |
| RPS13 | ribosomal protein S13 | -0.0201461 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0200937 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0200879 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0200585 |
| RPL21 | ribosomal protein L21 | -0.020042 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0200004 |
| MX2 | MX dynamin-like GTPase 2 | -0.0195657 |
| RPL36 | ribosomal protein L36 | -0.0195328 |
| RAD51B | RAD51 paralog B | -0.0192831 |
| PFN1 | profilin 1 | -0.019022 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.018598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0180955 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0178615 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0178236 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0177056 |
| S100A11 | S100 calcium binding protein A11 | -0.0176212 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0173428 |
| RPS29 | ribosomal protein S29 | -0.017253 |
| MX1 | MX dynamin-like GTPase 1 | -0.0172427 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.017207 |
| SBF2 | SET binding factor 2 | -0.017202 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0171322 |
| VIM | vimentin | -0.0170163 |
| JUP | junction plakoglobin | -0.0166116 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0165646 |
| RBM25 | RNA binding motif protein 25 | -0.0161793 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0159557 |
| RAI14 | retinoic acid induced 14 | -0.0157094 |
