| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.115722 |
| TXNRD1 | thioredoxin reductase 1 | 0.0854 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.073987 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0623767 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0557113 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0497977 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0491224 |
| SPAG9 | sperm associated antigen 9 | 0.0477138 |
| ASPH | aspartate beta-hydroxylase | 0.0473179 |
| RTN4 | reticulon 4 | 0.0450949 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0450736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0428329 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428274 |
| GDA | guanine deaminase | 0.039159 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348232 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0346213 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0340596 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0307056 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0304252 |
| NEK7 | NIMA-related kinase 7 | 0.0286603 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.0284037 |
| CENPF | centromere protein F, 350/400kDa | 0.0276677 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0275212 |
| MYOF | myoferlin | 0.0263031 |
| GOLGA4 | golgin A4 | 0.0257264 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0256651 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0253786 |
| GRAMD1B | GRAM domain containing 1B | 0.0249544 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0247664 |
| EFNA5 | ephrin-A5 | 0.0244451 |
| WDR43 | WD repeat domain 43 | 0.0234745 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0231582 |
| CD109 | CD109 molecule | 0.022853 |
| OGA | O-GlcNAcase | 0.0219914 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0219473 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0218258 |
| MKI67 | marker of proliferation Ki-67 | 0.0218052 |
| PTMA | prothymosin, alpha | 0.0217338 |
| ENAH | enabled homolog (Drosophila) | 0.021684 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0213127 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0211896 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0210797 |
| TNPO1 | transportin 1 | 0.0210183 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0209882 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0207581 |
| TPM3 | tropomyosin 3 | 0.0201171 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0200677 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0199625 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.019614 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0195873 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0194411 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0194406 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0192571 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0188281 |
| RPS12 | ribosomal protein S12 | 0.0188034 |
| SET | SET nuclear proto-oncogene | 0.0184762 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0181421 |
| RBM25 | RNA binding motif protein 25 | 0.0180596 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0180091 |
| YBX1 | Y box binding protein 1 | 0.0179204 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0176264 |
| FLNB | filamin B, beta | 0.0176107 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0174553 |
| PTEN | phosphatase and tensin homolog | 0.0173441 |
| XPO1 | exportin 1 | 0.017296 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0170917 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0168539 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.01683 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0168086 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0166913 |
| PLCB4 | phospholipase C, beta 4 | 0.0165974 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0164714 |
| HEATR1 | HEAT repeat containing 1 | 0.0164268 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0163964 |
| RPL37A | ribosomal protein L37a | 0.0163705 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0163587 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0163095 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0162854 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0162682 |
| ATP13A3 | ATPase type 13A3 | 0.016264 |
| NRCAM | neuronal cell adhesion molecule | 0.0161961 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0160734 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0160303 |
| CTSC | cathepsin C | 0.0158836 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0158664 |
| FLNA | filamin A, alpha | 0.01574 |
| TCERG1 | transcription elongation regulator 1 | 0.0156799 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0156219 |
| PTK2 | protein tyrosine kinase 2 | 0.0155869 |
| RPS6 | ribosomal protein S6 | 0.0155386 |
| PRDX1 | peroxiredoxin 1 | 0.015483 |
| MSN | moesin | 0.0154159 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0154099 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0153421 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0151221 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.015079 |
| MAP1B | microtubule-associated protein 1B | 0.0149978 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0148254 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0146338 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0146188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.225335 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.177419 |
| FN1 | fibronectin 1 | -0.0841011 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0806479 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0722835 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.06165 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0563391 |
| PDE10A | phosphodiesterase 10A | -0.0496299 |
| CDH13 | cadherin 13 | -0.0478028 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0454546 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0422559 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0400684 |
| AUTS2 | autism susceptibility candidate 2 | -0.0386021 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0374958 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0352566 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0335964 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0311137 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0305498 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.030065 |
| PCBP3 | poly(rC) binding protein 3 | -0.0289213 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0281994 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0281335 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0280871 |
| VCL | vinculin | -0.0274861 |
| SMAD2 | SMAD family member 2 | -0.0269314 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0264067 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0261039 |
| DST | dystonin | -0.0237354 |
| LSAMP | limbic system-associated membrane protein | -0.0234441 |
| PRELID2 | PRELI domain containing 2 | -0.0230921 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0228795 |
| CHL1 | cell adhesion molecule L1-like | -0.0220728 |
| MAP7 | microtubule-associated protein 7 | -0.0220067 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0214132 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0212172 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0204232 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0192087 |
| DENND1A | DENN/MADD domain containing 1A | -0.0190313 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0184512 |
| INTS6 | integrator complex subunit 6 | -0.0180902 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0179555 |
| NCKAP5 | NCK-associated protein 5 | -0.0179533 |
| RAD51B | RAD51 paralog B | -0.017911 |
| EXT1 | exostosin glycosyltransferase 1 | -0.017596 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0173828 |
| RAB31 | RAB31, member RAS oncogene family | -0.0165403 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0161566 |
| CUX1 | cut-like homeobox 1 | -0.0161164 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0160763 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0158656 |
| KIAA0825 | KIAA0825 | -0.0156903 |
| CADM2 | cell adhesion molecule 2 | -0.0155832 |
| PCDH15 | protocadherin-related 15 | -0.0154006 |
| COL5A2 | collagen, type V, alpha 2 | -0.0151598 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0151209 |
| AEBP2 | AE binding protein 2 | -0.0147637 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0146363 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0145057 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0144616 |
| GLRX | glutaredoxin (thioltransferase) | -0.014134 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0138583 |
| EPHA4 | EPH receptor A4 | -0.0137298 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0136517 |
| TENM3 | teneurin transmembrane protein 3 | -0.0133762 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.013367 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0131157 |
| XYLT1 | xylosyltransferase I | -0.0130463 |
| PCDH9 | protocadherin 9 | -0.0125376 |
| FAM107B | family with sequence similarity 107, member B | -0.0125345 |
| PDE7B | phosphodiesterase 7B | -0.0124988 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0124022 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0123986 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0123942 |
| STC1 | stanniocalcin 1 | -0.0122225 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0121187 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.012054 |
| TENM2 | teneurin transmembrane protein 2 | -0.0120242 |
| HDAC4 | histone deacetylase 4 | -0.0119871 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0116767 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0113751 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0112076 |
| STEAP1B | STEAP family member 1B | -0.0110758 |
| SVIL | supervillin | -0.0108551 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0108511 |
| NTN4 | netrin 4 | -0.0108058 |
| RTN1 | reticulon 1 | -0.0107987 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0107369 |
| OXSR1 | oxidative stress responsive 1 | -0.0106369 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0104964 |
| FSTL4 | follistatin-like 4 | -0.0104908 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.0104797 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0103325 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0101922 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0100734 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0100608 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0100067 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0100042 |
| SMYD3 | SET and MYND domain containing 3 | -0.00986715 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00978975 |
| RANBP17 | RAN binding protein 17 | -0.00978588 |
