| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119457 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0903364 |
| PDE10A | phosphodiesterase 10A | 0.0898449 |
| MATR3 | matrin 3 | 0.078623 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0684618 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0641152 |
| VMP1 | vacuole membrane protein 1 | 0.0600383 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0596367 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0580121 |
| FLNB | filamin B, beta | 0.0579754 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0576051 |
| RAB10 | RAB10, member RAS oncogene family | 0.0569368 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0553352 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0537093 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0536664 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0526381 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.052 |
| RPL37A | ribosomal protein L37a | 0.0505371 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0487826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0485061 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0466247 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0445388 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.042605 |
| USP15 | ubiquitin specific peptidase 15 | 0.042376 |
| PHIP | pleckstrin homology domain interacting protein | 0.0420056 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0416175 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0410868 |
| OLA1 | Obg-like ATPase 1 | 0.0403883 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0403686 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0401493 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0394453 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0389565 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037995 |
| ACTG1 | actin gamma 1 | 0.0370532 |
| RIN2 | Ras and Rab interactor 2 | 0.0369017 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0364635 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0357104 |
| RBM39 | RNA binding motif protein 39 | 0.0355647 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0355119 |
| RPL11 | ribosomal protein L11 | 0.0352102 |
| ENO1 | enolase 1, (alpha) | 0.0345163 |
| ATXN1 | ataxin 1 | 0.0342596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0332531 |
| TCERG1 | transcription elongation regulator 1 | 0.0322197 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0319652 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0317855 |
| RLF | rearranged L-myc fusion | 0.0315699 |
| AHNAK | AHNAK nucleoprotein | 0.0313617 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0306168 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0304005 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0293592 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0292052 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0288979 |
| XPO1 | exportin 1 | 0.0287241 |
| SQSTM1 | sequestosome 1 | 0.0283569 |
| MTMR3 | myotubularin related protein 3 | 0.0269162 |
| SRPK2 | SRSF protein kinase 2 | 0.0268267 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0265991 |
| SET | SET nuclear proto-oncogene | 0.0264804 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0263475 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0261818 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0260422 |
| PDS5B | PDS5 cohesin associated factor B | 0.0250211 |
| KIF1B | kinesin family member 1B | 0.0249465 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0249167 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0243906 |
| RPS6 | ribosomal protein S6 | 0.0242874 |
| TXNRD1 | thioredoxin reductase 1 | 0.0234434 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0233463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0222321 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0216106 |
| RPS23 | ribosomal protein S23 | 0.0212266 |
| NF1 | neurofibromin 1 | 0.0210599 |
| FBXO11 | F-box protein 11 | 0.0205189 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.020358 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0202371 |
| FOXO1 | forkhead box O1 | 0.0199654 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.019296 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0190655 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0189709 |
| GPC6 | glypican 6 | 0.0189149 |
| GOLGA4 | golgin A4 | 0.0187857 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0186693 |
| EMP1 | epithelial membrane protein 1 | 0.0180843 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0180253 |
| HELZ | helicase with zinc finger | 0.0175022 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0172798 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0172192 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0167601 |
| RBM15 | RNA binding motif protein 15 | 0.0166404 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0162218 |
| SETD5 | SET domain containing 5 | 0.0158985 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0158974 |
| ZNF292 | zinc finger protein 292 | 0.0157691 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0157343 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0156053 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0150781 |
| DTNA | dystrobrevin, alpha | 0.0150424 |
| RORA | RAR-related orphan receptor A | 0.015037 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0147922 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.198446 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16871 |
| FTL | ferritin, light polypeptide | -0.109322 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.088181 |
| CD44 | CD44 molecule (Indian blood group) | -0.0875471 |
| MT2A | metallothionein 2A | -0.0866921 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0836242 |
| MYO1E | myosin IE | -0.0828894 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0807457 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0777451 |
| RPS3 | ribosomal protein S3 | -0.0753012 |
| LDHA | lactate dehydrogenase A | -0.0728878 |
| MYO6 | myosin VI | -0.0690119 |
| FN1 | fibronectin 1 | -0.0687575 |
| HDAC9 | histone deacetylase 9 | -0.066054 |
| USP34 | ubiquitin specific peptidase 34 | -0.0659826 |
| TPM4 | tropomyosin 4 | -0.058597 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0575878 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0568606 |
| B2M | beta-2-microglobulin | -0.0540005 |
| RPLP1 | ribosomal protein, large, P1 | -0.0534657 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0529843 |
| RPL31 | ribosomal protein L31 | -0.0525202 |
| VIM | vimentin | -0.0521824 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0507802 |
| PKM | pyruvate kinase, muscle | -0.0488632 |
| VCL | vinculin | -0.048827 |
| CCNI | cyclin I | -0.0486883 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0456047 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0452041 |
| YBX3 | Y box binding protein 3 | -0.0450913 |
| PDE8A | phosphodiesterase 8A | -0.0442067 |
| RPS8 | ribosomal protein S8 | -0.0438944 |
| RPL23 | ribosomal protein L23 | -0.0434026 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.042734 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0423057 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0407236 |
| HLA-B | major histocompatibility complex, class I, B | -0.0401552 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0379803 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0374875 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0374793 |
| TMSB10 | thymosin beta 10 | -0.0364606 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0358806 |
| ARRDC3 | arrestin domain containing 3 | -0.0358145 |
| SBF2 | SET binding factor 2 | -0.0354085 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0342403 |
| SLTM | SAFB-like, transcription modulator | -0.0338637 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0337477 |
| RPL19 | ribosomal protein L19 | -0.0288873 |
| S100A9 | S100 calcium binding protein A9 | -0.0281462 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0280926 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0262622 |
| S100A10 | S100 calcium binding protein A10 | -0.0236357 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0230632 |
| MCL1 | myeloid cell leukemia 1 | -0.0223505 |
| PTK2 | protein tyrosine kinase 2 | -0.0216532 |
| RTN4 | reticulon 4 | -0.0215045 |
| FMNL2 | formin-like 2 | -0.0205179 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0187552 |
| RPLP2 | ribosomal protein, large, P2 | -0.0183205 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0178734 |
| PGK1 | phosphoglycerate kinase 1 | -0.017839 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0175671 |
| RPL35A | ribosomal protein L35a | -0.0173376 |
| RPL26 | ribosomal protein L26 | -0.0173284 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0165615 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.015711 |
| STC1 | stanniocalcin 1 | -0.015503 |
| POTEF | POTE ankyrin domain family, member F | -0.0154864 |
| TPR | translocated promoter region, nuclear basket protein | -0.0153392 |
| RPL12 | ribosomal protein L12 | -0.0145744 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0133344 |
| MAP4 | microtubule-associated protein 4 | -0.0130765 |
| RUNX1 | runt-related transcription factor 1 | -0.0122075 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0115936 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0114106 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.011306 |
| HDLBP | high density lipoprotein binding protein | -0.0111264 |
| MYOF | myoferlin | -0.0106123 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0100981 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0092155 |
| RPS12 | ribosomal protein S12 | -0.00917079 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.00891561 |
| CDK6 | cyclin-dependent kinase 6 | -0.00888424 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00773554 |
| MED13 | mediator complex subunit 13 | -0.0072102 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.00646384 |
| RPS19 | ribosomal protein S19 | -0.00561802 |
| OGA | O-GlcNAcase | -0.00529306 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00526262 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00467632 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0045734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00412477 |
| SMAD3 | SMAD family member 3 | -0.00382135 |
| EFNA5 | ephrin-A5 | -0.0037075 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00351012 |
| SPAG9 | sperm associated antigen 9 | -0.00313447 |
| DST | dystonin | -0.00307425 |
| FAM13A | family with sequence similarity 13, member A | -0.00281769 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0027007 |
