| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.140154 |
| SYT1 | synaptotagmin I | 0.0809592 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0743416 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0522242 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0464687 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0425189 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0421486 |
| THBS1 | thrombospondin 1 | 0.0421018 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0403311 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0398885 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.038895 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0356519 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0301142 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0299169 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0298683 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.028589 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0282239 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0278762 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0275543 |
| RPL19 | ribosomal protein L19 | 0.0263322 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0255619 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0246788 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0241715 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0238726 |
| CUX1 | cut-like homeobox 1 | 0.0237425 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0236304 |
| RPS4X | ribosomal protein S4, X-linked | 0.0231056 |
| MED12L | mediator complex subunit 12-like | 0.0226003 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0219803 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0214892 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0214654 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.021071 |
| RLIM | ring finger protein, LIM domain interacting | 0.0206184 |
| CCND1 | cyclin D1 | 0.0204469 |
| PTK2 | protein tyrosine kinase 2 | 0.020151 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0200676 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0196594 |
| WDR43 | WD repeat domain 43 | 0.0195855 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0193597 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0191815 |
| RPS23 | ribosomal protein S23 | 0.0191427 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0190733 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0188335 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0186827 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0181917 |
| NAV3 | neuron navigator 3 | 0.0179583 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0179315 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0179034 |
| LMNA | lamin A/C | 0.0177671 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0177123 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0176236 |
| MCM3 | minichromosome maintenance complex component 3 | 0.0175959 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0175396 |
| HBS1L | HBS1-like translational GTPase | 0.017286 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0172474 |
| CORO1C | coronin, actin binding protein, 1C | 0.0172408 |
| INHBA | inhibin, beta A | 0.0170914 |
| ANK2 | ankyrin 2, neuronal | 0.0169668 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0169617 |
| CDK6 | cyclin-dependent kinase 6 | 0.0166803 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0165815 |
| PRR16 | proline rich 16 | 0.0163959 |
| SPAG9 | sperm associated antigen 9 | 0.016214 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0161448 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0160154 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0159665 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0158026 |
| RPL10A | ribosomal protein L10a | 0.0156622 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0155281 |
| EGR1 | early growth response 1 | 0.0153869 |
| TJP1 | tight junction protein 1 | 0.0153782 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0153687 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.0152526 |
| GSE1 | Gse1 coiled-coil protein | 0.0152108 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0151696 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0151466 |
| IPO7 | importin 7 | 0.0151107 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0150343 |
| ZNF462 | zinc finger protein 462 | 0.0150331 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.014945 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0149148 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0147668 |
| RPLP1 | ribosomal protein, large, P1 | 0.0147217 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.014712 |
| HSPA1A | heat shock 70kDa protein 1A | 0.01468 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0146227 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0146085 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | 0.0145708 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0145282 |
| SNX29 | sorting nexin 29 | 0.0145157 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0145153 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0143228 |
| RCC1 | regulator of chromosome condensation 1 | 0.0142828 |
| BRCA1 | breast cancer 1, early onset | 0.0142584 |
| TENM3 | teneurin transmembrane protein 3 | 0.0141718 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0140881 |
| RIGI | RNA sensor RIG-I | 0.0140527 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0140337 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0139679 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0138966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | -0.0922872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0805182 |
| RPS2 | ribosomal protein S2 | -0.0680736 |
| PEG10 | paternally expressed 10 | -0.0680329 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0649788 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0648363 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0600906 |
| COL3A1 | collagen, type III, alpha 1 | -0.0594958 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0577942 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0571508 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0569221 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0568732 |
| SNX6 | sorting nexin 6 | -0.0568457 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0537335 |
| PTMA | prothymosin, alpha | -0.053316 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0501889 |
| OGA | O-GlcNAcase | -0.046673 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0450574 |
| VIM | vimentin | -0.0448106 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0445899 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0443506 |
| SRP54 | signal recognition particle 54kDa | -0.0441433 |
| PDGFC | platelet derived growth factor C | -0.0438096 |
| PGK1 | phosphoglycerate kinase 1 | -0.04371 |
| GPC3 | glypican 3 | -0.0423875 |
| HMGB2 | high mobility group box 2 | -0.0417031 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0400504 |
| NCKAP1 | NCK-associated protein 1 | -0.0393718 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0386634 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0360911 |
| RPS16 | ribosomal protein S16 | -0.035298 |
| CALR | calreticulin | -0.0352485 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0341157 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0338436 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0337528 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0336599 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0335692 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0331104 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326726 |
| LDHA | lactate dehydrogenase A | -0.0324403 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0321357 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0318472 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0316535 |
| R3HDM1 | R3H domain containing 1 | -0.0315222 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.031231 |
| PRKD1 | protein kinase D1 | -0.0306544 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0303151 |
| TPX2 | TPX2, microtubule-associated | -0.0302965 |
| THOC2 | THO complex 2 | -0.0300422 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0297762 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0294376 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0293417 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0292523 |
| CDC73 | cell division cycle 73 | -0.0289974 |
| COL1A2 | collagen, type I, alpha 2 | -0.028985 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0289841 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0289238 |
| ZNF217 | zinc finger protein 217 | -0.0285147 |
| BBX | bobby sox homolog (Drosophila) | -0.0281781 |
| ENAH | enabled homolog (Drosophila) | -0.0281255 |
| TMSB4X | thymosin beta 4, X-linked | -0.0277451 |
| RASAL2 | RAS protein activator like 2 | -0.0277365 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0277239 |
| ENO1 | enolase 1, (alpha) | -0.0277014 |
| CFL2 | cofilin 2 (muscle) | -0.0276024 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0274257 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0273935 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0273907 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.027323 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0270432 |
| RAD51B | RAD51 paralog B | -0.0269737 |
| RLF | rearranged L-myc fusion | -0.0269012 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0268695 |
| NTM | neurotrimin | -0.0267922 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0267654 |
| CEP192 | centrosomal protein 192kDa | -0.0267228 |
| PHF3 | PHD finger protein 3 | -0.0265838 |
| MAP4 | microtubule-associated protein 4 | -0.0264089 |
| RFPL4B | ret finger protein-like 4B | -0.0261416 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0258251 |
| TMEM165 | transmembrane protein 165 | -0.0257101 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0254439 |
| CENPF | centromere protein F, 350/400kDa | -0.0253227 |
| ABI2 | abl-interactor 2 | -0.0251054 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0249839 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0249052 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0249025 |
| RPL7 | ribosomal protein L7 | -0.0248585 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0248151 |
| CADM2 | cell adhesion molecule 2 | -0.0248025 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0247014 |
| SETD5 | SET domain containing 5 | -0.0245945 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0244269 |
| UBC | ubiquitin C | -0.0241868 |
| RBM39 | RNA binding motif protein 39 | -0.0240921 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0240567 |
| RPS12 | ribosomal protein S12 | -0.0235399 |
| CUL4B | cullin 4B | -0.0234691 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0232236 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0229942 |
