| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.155645 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.108907 |
| FBL | fibrillarin | 0.0945429 |
| RPS16 | ribosomal protein S16 | 0.0741274 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0682706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0659284 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0614126 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0548942 |
| GOLGA4 | golgin A4 | 0.0543574 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0507728 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0498623 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0493618 |
| CALR | calreticulin | 0.0460615 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0453636 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0412437 |
| ZFP36 | ZFP36 ring finger protein | 0.0412331 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0405247 |
| SPAG9 | sperm associated antigen 9 | 0.0399102 |
| YBX1 | Y box binding protein 1 | 0.0394829 |
| QKI | QKI, KH domain containing, RNA binding | 0.0376917 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0368347 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0367279 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0355516 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0355342 |
| SUCO | SUN domain containing ossification factor | 0.0352879 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0333217 |
| PCBP2 | poly(rC) binding protein 2 | 0.0332183 |
| SFTPA2 | surfactant protein A2 | 0.0327947 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0317405 |
| FOSL1 | FOS-like antigen 1 | 0.0311503 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306167 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0298406 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0296627 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0288858 |
| PLEC | plectin | 0.0285997 |
| CANX | calnexin | 0.0284819 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0279486 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0276255 |
| L1CAM | L1 cell adhesion molecule | 0.0271913 |
| NOP58 | NOP58 ribonucleoprotein | 0.0265298 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.026445 |
| RPL21 | ribosomal protein L21 | 0.0259979 |
| XPO1 | exportin 1 | 0.0258573 |
| SRP54 | signal recognition particle 54kDa | 0.025836 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0257141 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0254423 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0251762 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0251757 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0248931 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0244971 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0241858 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0240206 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0234084 |
| BRD2 | bromodomain containing 2 | 0.0233634 |
| USP3 | ubiquitin specific peptidase 3 | 0.0231401 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0228588 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.022724 |
| SEPTIN9 | septin 9 | 0.0226328 |
| ATP13A3 | ATPase type 13A3 | 0.0224809 |
| UPP1 | uridine phosphorylase 1 | 0.0223901 |
| HM13 | histocompatibility (minor) 13 | 0.0218924 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.021665 |
| HYOU1 | hypoxia up-regulated 1 | 0.0215428 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0215279 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0214903 |
| MSN | moesin | 0.0213624 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0211183 |
| WDR43 | WD repeat domain 43 | 0.020972 |
| CTBP2 | C-terminal binding protein 2 | 0.0207717 |
| TPM3 | tropomyosin 3 | 0.0207528 |
| COG5 | component of oligomeric golgi complex 5 | 0.0204842 |
| FMNL2 | formin-like 2 | 0.0202486 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0202081 |
| CCNL1 | cyclin L1 | 0.0200057 |
| YAP1 | Yes-associated protein 1 | 0.0199453 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0198849 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.019861 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0197743 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196035 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0195186 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0194707 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0193192 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0192635 |
| TFG | TRK-fused gene | 0.0192165 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0191805 |
| FLNB | filamin B, beta | 0.0189037 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0187518 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0186378 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0185726 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0185656 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0183951 |
| WASF2 | WAS protein family, member 2 | 0.0183774 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0182221 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181718 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0181301 |
| RPS2 | ribosomal protein S2 | 0.0180047 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.0179611 |
| DSTN | destrin (actin depolymerizing factor) | 0.0177593 |
| RPS12 | ribosomal protein S12 | 0.0177531 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.017646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.333464 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.122436 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.108719 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106189 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0899397 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0813257 |
| VIM | vimentin | -0.0787231 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0782622 |
| CD44 | CD44 molecule (Indian blood group) | -0.0760455 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0759714 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0633414 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0629125 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0614965 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0613349 |
| ASPH | aspartate beta-hydroxylase | -0.059622 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0573281 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0555754 |
| RPL35A | ribosomal protein L35a | -0.0521557 |
| EGR1 | early growth response 1 | -0.0519338 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0510748 |
| HMGA2 | high mobility group AT-hook 2 | -0.048027 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0471968 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0459104 |
| ACTN4 | actinin, alpha 4 | -0.0453274 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0442485 |
| TMSB10 | thymosin beta 10 | -0.0441658 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0440595 |
| OSMR | oncostatin M receptor | -0.0436555 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0435771 |
| ZNF780B | zinc finger protein 780B | -0.0434351 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.043298 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0407846 |
| SMYD3 | SET and MYND domain containing 3 | -0.0390181 |
| PHF14 | PHD finger protein 14 | -0.0389329 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0369478 |
| JMJD1C | jumonji domain containing 1C | -0.0348247 |
| FHL2 | four and a half LIM domains 2 | -0.0346196 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0345519 |
| MYO1E | myosin IE | -0.0344306 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0338569 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.033799 |
| RIGI | RNA sensor RIG-I | -0.0336884 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0334871 |
| MCL1 | myeloid cell leukemia 1 | -0.0333311 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0331665 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0330474 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0309166 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0309087 |
| AHNAK | AHNAK nucleoprotein | -0.030896 |
| VMP1 | vacuole membrane protein 1 | -0.0308752 |
| TPM1 | tropomyosin 1 (alpha) | -0.0308211 |
| RPS24 | ribosomal protein S24 | -0.0307886 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0307539 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0306301 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0304814 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.029968 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0299339 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0294353 |
| ZNF644 | zinc finger protein 644 | -0.0293027 |
| ACTG1 | actin gamma 1 | -0.0292381 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0287049 |
| PRSS23 | protease, serine, 23 | -0.0284195 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0281275 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.028022 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0277504 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0273956 |
| ATG7 | autophagy related 7 | -0.0273874 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0273736 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0270445 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0269035 |
| ITGB5 | integrin, beta 5 | -0.0268822 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0266999 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0261602 |
| RAD51B | RAD51 paralog B | -0.0260943 |
| EFNA5 | ephrin-A5 | -0.0260349 |
| RAB31 | RAB31, member RAS oncogene family | -0.0254113 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.024779 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0247681 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0242917 |
| NF1 | neurofibromin 1 | -0.0242215 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0238649 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0233889 |
| PRELID2 | PRELI domain containing 2 | -0.0233672 |
| HDAC9 | histone deacetylase 9 | -0.0233278 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0231378 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0230542 |
| ITGAV | integrin, alpha V | -0.0229701 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0229629 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0224351 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0223457 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0222443 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0218285 |
| EHBP1 | EH domain binding protein 1 | -0.0217664 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0216836 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0213909 |
| EXOC4 | exocyst complex component 4 | -0.0213469 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -0.0212651 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0210028 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0209274 |
| ZNF546 | zinc finger protein 546 | -0.0205257 |
