| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.158577 |
| LAMB3 | laminin, beta 3 | 0.137837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102273 |
| EZR | ezrin | 0.0926917 |
| NDRG1 | N-myc downstream regulated 1 | 0.081186 |
| MYO6 | myosin VI | 0.0793979 |
| AHNAK | AHNAK nucleoprotein | 0.0696138 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0680786 |
| CANX | calnexin | 0.0679403 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0678089 |
| KRT18 | keratin 18, type I | 0.0617332 |
| NAV2 | neuron navigator 2 | 0.0615808 |
| ANLN | anillin, actin binding protein | 0.0595377 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0595138 |
| OGA | O-GlcNAcase | 0.0588852 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.058694 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0564595 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0563772 |
| RUNX1 | runt-related transcription factor 1 | 0.0550943 |
| ANXA2 | annexin A2 | 0.0545658 |
| GOLGA4 | golgin A4 | 0.0534311 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.053299 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0518744 |
| KRT17 | keratin 17, type I | 0.0506057 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0489086 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0483548 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0476376 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0469522 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0468608 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0458042 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0450513 |
| CALR | calreticulin | 0.0445459 |
| FAM3C | family with sequence similarity 3, member C | 0.0444542 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0444336 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442331 |
| XPO1 | exportin 1 | 0.0429761 |
| RIOK3 | RIO kinase 3 | 0.0421779 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0415516 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.040417 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0403919 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0401162 |
| MKI67 | marker of proliferation Ki-67 | 0.0390037 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0385967 |
| JMJD1C | jumonji domain containing 1C | 0.0381925 |
| EMP1 | epithelial membrane protein 1 | 0.0380511 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0378968 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0377479 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0368538 |
| RLF | rearranged L-myc fusion | 0.0366041 |
| TMF1 | TATA element modulatory factor 1 | 0.0363206 |
| ECT2 | epithelial cell transforming 2 | 0.0358991 |
| MYOF | myoferlin | 0.0354956 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0353107 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0350719 |
| RBM39 | RNA binding motif protein 39 | 0.0341785 |
| SPAG9 | sperm associated antigen 9 | 0.0340275 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0331944 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0330691 |
| PHF3 | PHD finger protein 3 | 0.0328616 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0328354 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0326598 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323084 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0321176 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0312269 |
| CENPF | centromere protein F, 350/400kDa | 0.0304546 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0302782 |
| SLTM | SAFB-like, transcription modulator | 0.0302434 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0299522 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0291535 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0289588 |
| ATP11B | ATPase, class VI, type 11B | 0.0281963 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0281272 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0277722 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0277196 |
| PLEC | plectin | 0.0275528 |
| SUCO | SUN domain containing ossification factor | 0.0272716 |
| TOP1 | topoisomerase (DNA) I | 0.0270948 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0270669 |
| ARRDC3 | arrestin domain containing 3 | 0.0268904 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0264375 |
| RTN4 | reticulon 4 | 0.0263367 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0260105 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0257873 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0255841 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0253842 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0252972 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.02524 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0249899 |
| FLNB | filamin B, beta | 0.0248909 |
| HMGB2 | high mobility group box 2 | 0.024875 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0247825 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0247375 |
| DIAPH3 | diaphanous-related formin 3 | 0.024737 |
| SRP54 | signal recognition particle 54kDa | 0.0246806 |
| CALU | calumenin | 0.0242524 |
| SMAD3 | SMAD family member 3 | 0.0241702 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0241504 |
| ITGB4 | integrin, beta 4 | 0.0239647 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0239627 |
| PGK1 | phosphoglycerate kinase 1 | 0.0239522 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.145995 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.107385 |
| RPL35A | ribosomal protein L35a | -0.0946789 |
| MUC4 | mucin 4, cell surface associated | -0.087415 |
| ACTG1 | actin gamma 1 | -0.0873562 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0871786 |
| LAMA4 | laminin, alpha 4 | -0.0833255 |
| TMSB10 | thymosin beta 10 | -0.0789053 |
| RNF213 | ring finger protein 213 | -0.067092 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0659399 |
| RPL23 | ribosomal protein L23 | -0.0638954 |
| PLSCR1 | phospholipid scramblase 1 | -0.0620233 |
| MX2 | MX dynamin-like GTPase 2 | -0.0611256 |
| FN1 | fibronectin 1 | -0.0555718 |
| POTEF | POTE ankyrin domain family, member F | -0.0542229 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0538841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0524377 |
| RPS6 | ribosomal protein S6 | -0.0517697 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0506193 |
| LMO7 | LIM domain 7 | -0.0500865 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.049632 |
| B2M | beta-2-microglobulin | -0.047733 |
| HLA-B | major histocompatibility complex, class I, B | -0.0476563 |
| FTL | ferritin, light polypeptide | -0.0472505 |
| MX1 | MX dynamin-like GTPase 1 | -0.0470775 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0463076 |
| RPS19 | ribosomal protein S19 | -0.0461619 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0455957 |
| MUC16 | mucin 16, cell surface associated | -0.044365 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0442871 |
| HMGA1 | high mobility group AT-hook 1 | -0.0438559 |
| RPS21 | ribosomal protein S21 | -0.0436329 |
| RIGI | RNA sensor RIG-I | -0.0431865 |
| OSMR | oncostatin M receptor | -0.0428654 |
| MYO1E | myosin IE | -0.0427287 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0426114 |
| RPS13 | ribosomal protein S13 | -0.0423933 |
| ETV6 | ets variant 6 | -0.041586 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0413962 |
| RPL34 | ribosomal protein L34 | -0.0410696 |
| SYT14 | synaptotagmin XIV | -0.0407681 |
| RPS8 | ribosomal protein S8 | -0.0398201 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0396501 |
| RPL31 | ribosomal protein L31 | -0.0394811 |
| IFI44L | interferon-induced protein 44-like | -0.0383575 |
| VCL | vinculin | -0.0383142 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0382689 |
| IFI44 | interferon-induced protein 44 | -0.0378906 |
| RPL37A | ribosomal protein L37a | -0.0372659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0370935 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0367909 |
| MT2A | metallothionein 2A | -0.0366175 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0354022 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0352808 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0352799 |
| KRT7 | keratin 7, type II | -0.0350222 |
| RPS14 | ribosomal protein S14 | -0.0346176 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0340522 |
| RPS23 | ribosomal protein S23 | -0.0339011 |
| CD44 | CD44 molecule (Indian blood group) | -0.0337497 |
| SP100 | SP100 nuclear antigen | -0.0337382 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0334162 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0319677 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0308866 |
| C3 | complement component 3 | -0.0308758 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0306174 |
| RPLP1 | ribosomal protein, large, P1 | -0.0303574 |
| TJP1 | tight junction protein 1 | -0.0301664 |
| KRT19 | keratin 19, type I | -0.0292457 |
| RPS24 | ribosomal protein S24 | -0.0291596 |
| PLAT | plasminogen activator, tissue | -0.0288583 |
| RPL9 | ribosomal protein L9 | -0.0287213 |
| INTS6 | integrator complex subunit 6 | -0.0279357 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0276815 |
| SVIL | supervillin | -0.0275162 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0265213 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0261987 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0260746 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0260496 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0259396 |
| EGR1 | early growth response 1 | -0.0258425 |
| RPL28 | ribosomal protein L28 | -0.0257374 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0255951 |
| RPL37 | ribosomal protein L37 | -0.0255898 |
| RPS17 | ribosomal protein S17 | -0.0253737 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0248699 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0247666 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0247518 |
| TMSB4X | thymosin beta 4, X-linked | -0.0246995 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0246248 |
| EFNA5 | ephrin-A5 | -0.024493 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0244537 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0243678 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241598 |
| RPS25 | ribosomal protein S25 | -0.0241282 |
| RPL32 | ribosomal protein L32 | -0.0238916 |
| S100A9 | S100 calcium binding protein A9 | -0.023869 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0238646 |
| TAPBP | TAP binding protein (tapasin) | -0.0237777 |
| SGMS2 | sphingomyelin synthase 2 | -0.0235385 |
