| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.120468 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.101277 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0924742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0854151 |
| ACTG1 | actin gamma 1 | 0.0771432 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0644034 |
| JMJD1C | jumonji domain containing 1C | 0.0608041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0587916 |
| PGK1 | phosphoglycerate kinase 1 | 0.0530309 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0520075 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0508536 |
| FRMD4A | FERM domain containing 4A | 0.05037 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0496203 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0474282 |
| NDRG1 | N-myc downstream regulated 1 | 0.0469617 |
| LAMB3 | laminin, beta 3 | 0.046235 |
| NUP58 | nucleoporin 58 | 0.0452715 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0441066 |
| ZNF292 | zinc finger protein 292 | 0.0427098 |
| FRMD6 | FERM domain containing 6 | 0.0417584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0411481 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0405577 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0375974 |
| OGA | O-GlcNAcase | 0.0365108 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0364722 |
| ARFGEF3 | ARFGEF family member 3 | 0.036118 |
| PRELID2 | PRELI domain containing 2 | 0.0354949 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0354902 |
| CALD1 | caldesmon 1 | 0.0346961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0340045 |
| TTR | transthyretin | 0.0340033 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0334448 |
| CALU | calumenin | 0.0329693 |
| TPD52 | tumor protein D52 | 0.0326433 |
| CAPRIN2 | caprin family member 2 | 0.0319689 |
| FLNA | filamin A, alpha | 0.0319194 |
| TMF1 | TATA element modulatory factor 1 | 0.0302734 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0302262 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0298469 |
| GOLGA2 | golgin A2 | 0.029553 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0293796 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0289938 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0289656 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.028658 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0283543 |
| LDHA | lactate dehydrogenase A | 0.0276205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270966 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0267453 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0255032 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0252832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252027 |
| WDR26 | WD repeat domain 26 | 0.0251382 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0250586 |
| CANX | calnexin | 0.0246626 |
| PHF3 | PHD finger protein 3 | 0.0236643 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.023564 |
| RPL13A | ribosomal protein L13a | 0.0232347 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0231945 |
| WDR45B | WD repeat domain 45B | 0.0230941 |
| YEATS2 | YEATS domain containing 2 | 0.0230875 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0230469 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.022965 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.0225596 |
| GPATCH2L | G patch domain containing 2-like | 0.0223904 |
| DGKI | diacylglycerol kinase, iota | 0.0222387 |
| CREB5 | cAMP responsive element binding protein 5 | 0.022173 |
| NABP1 | nucleic acid binding protein 1 | 0.0219808 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0218443 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0216281 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0215819 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.020251 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0202219 |
| CCDC47 | coiled-coil domain containing 47 | 0.0201147 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0198775 |
| TMEM263 | transmembrane protein 263 | 0.0196055 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0194931 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.019289 |
| PRKCE | protein kinase C, epsilon | 0.0188465 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0186384 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0185616 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0185329 |
| TUT7 | terminal uridylyl transferase 7 | 0.0184197 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0174982 |
| SETX | senataxin | 0.017018 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0166507 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0165872 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0164752 |
| CEP135 | centrosomal protein 135kDa | 0.0163663 |
| CEP95 | centrosomal protein 95kDa | 0.0163375 |
| ENO1 | enolase 1, (alpha) | 0.0163132 |
| SUCO | SUN domain containing ossification factor | 0.0162717 |
| TAOK1 | TAO kinase 1 | 0.016224 |
| HDLBP | high density lipoprotein binding protein | 0.0161311 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0160098 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0159785 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0158387 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0156242 |
| INSIG2 | insulin induced gene 2 | 0.0153974 |
| CLTC | clathrin, heavy chain (Hc) | 0.015381 |
| HLA-A | major histocompatibility complex, class I, A | 0.0151929 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.14568 |
| NAV3 | neuron navigator 3 | -0.0902752 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0876654 |
| TXNRD1 | thioredoxin reductase 1 | -0.0698508 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0690501 |
| PTK2 | protein tyrosine kinase 2 | -0.0617123 |
| RPL35A | ribosomal protein L35a | -0.0601482 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.059252 |
| WDR43 | WD repeat domain 43 | -0.0558021 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.055336 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0512375 |
| SRPK2 | SRSF protein kinase 2 | -0.0491847 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476871 |
| PTMA | prothymosin, alpha | -0.0468936 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0451029 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0444225 |
| IPO7 | importin 7 | -0.0442224 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0432604 |
| ATP13A3 | ATPase type 13A3 | -0.0403619 |
| RPS21 | ribosomal protein S21 | -0.0382588 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0371165 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0371073 |
| TMSB10 | thymosin beta 10 | -0.0368653 |
| OLA1 | Obg-like ATPase 1 | -0.0366224 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0366173 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0363015 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0360475 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.034808 |
| RPL23 | ribosomal protein L23 | -0.0346352 |
| MATR3 | matrin 3 | -0.0343727 |
| RPS6 | ribosomal protein S6 | -0.0343718 |
| NCKAP1 | NCK-associated protein 1 | -0.0342615 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0335831 |
| TCF12 | transcription factor 12 | -0.0330122 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0329303 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0324315 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0319735 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0318919 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0318562 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0315944 |
| NUP153 | nucleoporin 153kDa | -0.0312517 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0308655 |
| GPHN | gephyrin | -0.0306608 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0305885 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0305647 |
| PARD3 | par-3 family cell polarity regulator | -0.0303455 |
| DIAPH3 | diaphanous-related formin 3 | -0.0303008 |
| RBM25 | RNA binding motif protein 25 | -0.0299104 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0299048 |
| PFN1 | profilin 1 | -0.0295806 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0294463 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0290871 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0290334 |
| NOP58 | NOP58 ribonucleoprotein | -0.0288026 |
| RPS24 | ribosomal protein S24 | -0.0285662 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0284671 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0282081 |
| RPL8 | ribosomal protein L8 | -0.0277445 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0274256 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0272258 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0272096 |
| RHEB | Ras homolog enriched in brain | -0.027053 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0269455 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0268242 |
| PDS5B | PDS5 cohesin associated factor B | -0.0267526 |
| PKM | pyruvate kinase, muscle | -0.02674 |
| TOP1 | topoisomerase (DNA) I | -0.02665 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0264336 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0262867 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262839 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0262219 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0261954 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0261249 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0260025 |
| SLMAP | sarcolemma associated protein | -0.0257227 |
| RAB3IP | RAB3A interacting protein | -0.0256908 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0256454 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0254506 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0251685 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0251207 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.02512 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0250351 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0247525 |
| SRPK1 | SRSF protein kinase 1 | -0.0247502 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0247438 |
| RASA2 | RAS p21 protein activator 2 | -0.0246678 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0245673 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0245151 |
| FTL | ferritin, light polypeptide | -0.0244832 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0243915 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.024058 |
| RPL35 | ribosomal protein L35 | -0.0239611 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0238531 |
| RPS19 | ribosomal protein S19 | -0.0238382 |
| NOP56 | NOP56 ribonucleoprotein | -0.0236166 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0234604 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0232293 |
| RPLP2 | ribosomal protein, large, P2 | -0.0231838 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0231488 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0231328 |
