| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.20295 |
| CD109 | CD109 molecule | 0.105647 |
| VIM | vimentin | 0.0917246 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0828523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0786095 |
| NDRG1 | N-myc downstream regulated 1 | 0.0777084 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0746423 |
| GOLGA4 | golgin A4 | 0.0716394 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0630502 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0623338 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0572535 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.057163 |
| VEGFA | vascular endothelial growth factor A | 0.0546462 |
| POTEF | POTE ankyrin domain family, member F | 0.0541027 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0532331 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0526846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0502133 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0498536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.047952 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0471919 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0471763 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0469437 |
| PKM | pyruvate kinase, muscle | 0.0462981 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0455971 |
| CCNL1 | cyclin L1 | 0.0450921 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0443652 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0439123 |
| RYBP | RING1 and YY1 binding protein | 0.0435433 |
| ADM | adrenomedullin | 0.041859 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0410883 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.040349 |
| CALR | calreticulin | 0.0400062 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0377637 |
| STC1 | stanniocalcin 1 | 0.0373076 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0372569 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.037158 |
| SETD5 | SET domain containing 5 | 0.0365451 |
| MYOF | myoferlin | 0.0362121 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0359252 |
| MSN | moesin | 0.0347412 |
| EGR1 | early growth response 1 | 0.0346858 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0344164 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.034262 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0341807 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0333167 |
| ZNF292 | zinc finger protein 292 | 0.0331229 |
| COPA | coatomer protein complex, subunit alpha | 0.0331162 |
| WAC | WW domain containing adaptor with coiled-coil | 0.033059 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0322747 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0321119 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0315493 |
| FAM13A | family with sequence similarity 13, member A | 0.0315403 |
| TFG | TRK-fused gene | 0.03141 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0313033 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0307612 |
| MMP12 | matrix metallopeptidase 12 | 0.0306935 |
| MEF2A | myocyte enhancer factor 2A | 0.0304669 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0304385 |
| FMNL2 | formin-like 2 | 0.0299639 |
| PLEC | plectin | 0.0299434 |
| USP3 | ubiquitin specific peptidase 3 | 0.0298681 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0297198 |
| INSIG2 | insulin induced gene 2 | 0.0295301 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0295028 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0294624 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0294378 |
| TPM3 | tropomyosin 3 | 0.0292324 |
| BRD2 | bromodomain containing 2 | 0.0281705 |
| COL1A2 | collagen, type I, alpha 2 | 0.0281535 |
| DSTN | destrin (actin depolymerizing factor) | 0.0281492 |
| FAM162A | family with sequence similarity 162, member A | 0.0278845 |
| SRP54 | signal recognition particle 54kDa | 0.0277892 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.027776 |
| H1-0 | H1.0 linker histone | 0.0274411 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0273254 |
| MMP2 | matrix metallopeptidase 2 | 0.0272998 |
| RBM39 | RNA binding motif protein 39 | 0.0270996 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0270929 |
| HELZ | helicase with zinc finger | 0.0269406 |
| XPO1 | exportin 1 | 0.0267614 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0265687 |
| JUN | jun proto-oncogene | 0.0263662 |
| PCBP2 | poly(rC) binding protein 2 | 0.0262312 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0257857 |
| YBX1 | Y box binding protein 1 | 0.025265 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0252208 |
| ATP13A3 | ATPase type 13A3 | 0.0252058 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0251536 |
| NOP58 | NOP58 ribonucleoprotein | 0.0251332 |
| FOSL1 | FOS-like antigen 1 | 0.0250389 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.024985 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0246389 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.024254 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0241195 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0240108 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0238272 |
| FLNA | filamin A, alpha | 0.0235104 |
| PLIN2 | perilipin 2 | 0.0234424 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0233916 |
| CCDC88A | coiled-coil domain containing 88A | 0.0230594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.150087 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0885717 |
| FRMD4A | FERM domain containing 4A | -0.0874905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0706833 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0696014 |
| CD44 | CD44 molecule (Indian blood group) | -0.0693777 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0641886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0634058 |
| FAM20C | family with sequence similarity 20, member C | -0.0575284 |
| ASPH | aspartate beta-hydroxylase | -0.0530401 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0527394 |
| TMSB10 | thymosin beta 10 | -0.0505465 |
| HLA-B | major histocompatibility complex, class I, B | -0.0496625 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0466496 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0461556 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0440515 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0406553 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0404295 |
| NRP1 | neuropilin 1 | -0.0390131 |
| AFAP1 | actin filament associated protein 1 | -0.0371653 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0365868 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0361149 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0352048 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.035126 |
| GLIS3 | GLIS family zinc finger 3 | -0.034614 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0343413 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0329082 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0328648 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326927 |
| TPM1 | tropomyosin 1 (alpha) | -0.0326225 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0324619 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.032273 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0318866 |
| SMAD3 | SMAD family member 3 | -0.0314659 |
| RPL35A | ribosomal protein L35a | -0.0312435 |
| OSMR | oncostatin M receptor | -0.0307547 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0302765 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.029978 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0296369 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0294397 |
| IL1B | interleukin 1, beta | -0.0286765 |
| FHIT | fragile histidine triad | -0.0284695 |
| SVIL | supervillin | -0.0275314 |
| SSH1 | slingshot protein phosphatase 1 | -0.0267606 |
| RAD51B | RAD51 paralog B | -0.0265161 |
| RPS21 | ribosomal protein S21 | -0.0248388 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0245914 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.024209 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0232394 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0230418 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221531 |
| HDAC8 | histone deacetylase 8 | -0.0221478 |
| PLSCR1 | phospholipid scramblase 1 | -0.0221009 |
| SMYD3 | SET and MYND domain containing 3 | -0.0220098 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.021949 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0219397 |
| HMGA2 | high mobility group AT-hook 2 | -0.0218113 |
| CDCP1 | CUB domain containing protein 1 | -0.0215465 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.021407 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0213688 |
| IFI44 | interferon-induced protein 44 | -0.0209609 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0208685 |
| VCL | vinculin | -0.0208502 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0206803 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0205562 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0203413 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0202178 |
| SP100 | SP100 nuclear antigen | -0.020136 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0201295 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0200743 |
| RPL34 | ribosomal protein L34 | -0.0199368 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0198361 |
| RRBP1 | ribosome binding protein 1 | -0.0197905 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0197574 |
| RPS24 | ribosomal protein S24 | -0.0197267 |
| NAV1 | neuron navigator 1 | -0.0196389 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0196147 |
| TP63 | tumor protein p63 | -0.0195715 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0193423 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0192635 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0192537 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0191023 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0190798 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0190671 |
| ATG7 | autophagy related 7 | -0.0190306 |
| TMEM178B | transmembrane protein 178B | -0.0190046 |
| METTL15 | methyltransferase like 15 | -0.0187631 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0186782 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0186602 |
| XAF1 | XIAP associated factor 1 | -0.01849 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.018488 |
| NF1 | neurofibromin 1 | -0.0183483 |
| ATM | ATM serine/threonine kinase | -0.018237 |
| IER3 | immediate early response 3 | -0.018212 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0181899 |
| IFI44L | interferon-induced protein 44-like | -0.0181384 |
| RPS19 | ribosomal protein S19 | -0.0177328 |
| RIGI | RNA sensor RIG-I | -0.0177044 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0176021 |
| RPL23 | ribosomal protein L23 | -0.0174695 |
