| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.229681 |
| MSI2 | musashi RNA-binding protein 2 | 0.0907153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0898965 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0644703 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0570608 |
| FMNL2 | formin-like 2 | 0.0544534 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0492948 |
| GOLGA4 | golgin A4 | 0.0481444 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0438114 |
| CADM1 | cell adhesion molecule 1 | 0.0424108 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0416396 |
| SBF2 | SET binding factor 2 | 0.0409415 |
| SFTPA2 | surfactant protein A2 | 0.0407965 |
| KAZN | kazrin, periplakin interacting protein | 0.0389832 |
| PLEC | plectin | 0.0389534 |
| LSAMP | limbic system-associated membrane protein | 0.0384999 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0350312 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0346343 |
| HELZ | helicase with zinc finger | 0.0346088 |
| JMJD1C | jumonji domain containing 1C | 0.0330781 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0323718 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0322348 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0321715 |
| NRG3 | neuregulin 3 | 0.0319229 |
| SEPTIN9 | septin 9 | 0.0309592 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0298016 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0297032 |
| FAM13A | family with sequence similarity 13, member A | 0.0296687 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0296395 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0295395 |
| OGA | O-GlcNAcase | 0.0290896 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0288108 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0286459 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0274669 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0274472 |
| RLIM | ring finger protein, LIM domain interacting | 0.0273577 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0272928 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0272827 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0271828 |
| TOB2 | transducer of ERBB2, 2 | 0.0270741 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0267865 |
| CABIN1 | calcineurin binding protein 1 | 0.0267025 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0265383 |
| MMP12 | matrix metallopeptidase 12 | 0.0264609 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0263639 |
| YEATS2 | YEATS domain containing 2 | 0.0260473 |
| DENND1A | DENN/MADD domain containing 1A | 0.0259612 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0259506 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0254655 |
| FLNA | filamin A, alpha | 0.0253107 |
| CFAP20DC | CFAP20 domain containing | 0.0252851 |
| FHIT | fragile histidine triad | 0.0252105 |
| FLNB | filamin B, beta | 0.0248528 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0247986 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0246636 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0245108 |
| NGLY1 | N-glycanase 1 | 0.0244433 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0240337 |
| RAD51B | RAD51 paralog B | 0.0237514 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.023562 |
| CSNK1E | casein kinase 1, epsilon | 0.0234183 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0233721 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.023335 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0232685 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0230554 |
| SETD5 | SET domain containing 5 | 0.0228403 |
| CD109 | CD109 molecule | 0.0228192 |
| SEC24A | SEC24 family member A | 0.0228019 |
| COPA | coatomer protein complex, subunit alpha | 0.0226393 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0226322 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0225547 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0225213 |
| VEGFA | vascular endothelial growth factor A | 0.022521 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0222593 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0219014 |
| CTBP2 | C-terminal binding protein 2 | 0.0218897 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0218768 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0217894 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0217001 |
| PHF21A | PHD finger protein 21A | 0.0215047 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0214531 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0213966 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.021144 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0210607 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.020888 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0207849 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0207358 |
| DST | dystonin | 0.0204911 |
| USP3 | ubiquitin specific peptidase 3 | 0.0204702 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0197063 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0196117 |
| SRP54 | signal recognition particle 54kDa | 0.019075 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0189445 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0184879 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0183541 |
| HPCAL1 | hippocalcin-like 1 | 0.0180935 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0179434 |
| ZNF292 | zinc finger protein 292 | 0.0178995 |
| TMF1 | TATA element modulatory factor 1 | 0.0177933 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0177188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.145134 |
| MT2A | metallothionein 2A | -0.135358 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.126011 |
| UBC | ubiquitin C | -0.111025 |
| FMN1 | formin 1 | -0.10893 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0985436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0974431 |
| TXNRD1 | thioredoxin reductase 1 | -0.096581 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.094623 |
| TMSB10 | thymosin beta 10 | -0.0907513 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.075307 |
| ENO1 | enolase 1, (alpha) | -0.0698301 |
| RPS27A | ribosomal protein S27a | -0.0622104 |
| CD44 | CD44 molecule (Indian blood group) | -0.0598827 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0595061 |
| RPL23 | ribosomal protein L23 | -0.0578429 |
| RPS3 | ribosomal protein S3 | -0.0554319 |
| CCND1 | cyclin D1 | -0.0550128 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0517294 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0505315 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0495471 |
| PCBP2 | poly(rC) binding protein 2 | -0.0454788 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0394713 |
| PKM | pyruvate kinase, muscle | -0.0387319 |
| RPLP1 | ribosomal protein, large, P1 | -0.0383207 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0379219 |
| EMP1 | epithelial membrane protein 1 | -0.0377632 |
| APOD | apolipoprotein D | -0.0372351 |
| RUNX1 | runt-related transcription factor 1 | -0.0359029 |
| HDAC9 | histone deacetylase 9 | -0.034766 |
| POTEF | POTE ankyrin domain family, member F | -0.0338958 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0337839 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0337469 |
| MT1X | metallothionein 1X | -0.0335985 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0334086 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0327335 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0305447 |
| RPS13 | ribosomal protein S13 | -0.0300315 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0293449 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0292466 |
| RASAL2 | RAS protein activator like 2 | -0.0291782 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0290918 |
| FTL | ferritin, light polypeptide | -0.02889 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0283285 |
| VMP1 | vacuole membrane protein 1 | -0.0281876 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0276096 |
| BPTF | bromodomain PHD finger transcription factor | -0.0273809 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265461 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0265328 |
| B2M | beta-2-microglobulin | -0.0264916 |
| RPL31 | ribosomal protein L31 | -0.0264011 |
| ACTN4 | actinin, alpha 4 | -0.0262823 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0262467 |
| ERBIN | erbb2 interacting protein | -0.0261207 |
| IPO7 | importin 7 | -0.0261077 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0257439 |
| IER3 | immediate early response 3 | -0.0256092 |
| RPS8 | ribosomal protein S8 | -0.025154 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0248236 |
| SQSTM1 | sequestosome 1 | -0.0248084 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.024756 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0247524 |
| DIAPH1 | diaphanous-related formin 1 | -0.0244915 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0243586 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0236406 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0232107 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0231416 |
| RPS23 | ribosomal protein S23 | -0.0230889 |
| RPLP2 | ribosomal protein, large, P2 | -0.0228438 |
| RPL5 | ribosomal protein L5 | -0.0227964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0225557 |
| RACK1 | receptor for activated C kinase 1 | -0.0220286 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0219712 |
| FRMD4A | FERM domain containing 4A | -0.0219315 |
| FRMD5 | FERM domain containing 5 | -0.0218226 |
| NAV2 | neuron navigator 2 | -0.0214825 |
| RPS21 | ribosomal protein S21 | -0.0210187 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0209706 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0207502 |
| RPL32 | ribosomal protein L32 | -0.0206918 |
| KLF6 | Kruppel-like factor 6 | -0.0206194 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0204513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0203592 |
| RPL15 | ribosomal protein L15 | -0.0203365 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0201921 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0201179 |
| RTN4 | reticulon 4 | -0.0199074 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0194884 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0193244 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0188054 |
| EXOC6B | exocyst complex component 6B | -0.0187071 |
| RPL36A | ribosomal protein L36a | -0.0185767 |
| LDHA | lactate dehydrogenase A | -0.0184276 |
| FUS | FUS RNA binding protein | -0.0182914 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0182587 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0182468 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0181353 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0179068 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0177725 |
