| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.112383 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0806603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0744779 |
| ANK2 | ankyrin 2, neuronal | 0.073658 |
| GOLGA4 | golgin A4 | 0.0676324 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0645999 |
| ZNF292 | zinc finger protein 292 | 0.0636769 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0628328 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0574295 |
| NUP58 | nucleoporin 58 | 0.0568881 |
| FLNB | filamin B, beta | 0.054708 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0491266 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0482379 |
| EZR | ezrin | 0.0460812 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0443519 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0434934 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0429436 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0429161 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0426581 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0420721 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0417352 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0410395 |
| JMJD1C | jumonji domain containing 1C | 0.0410042 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0406132 |
| PGK1 | phosphoglycerate kinase 1 | 0.0386214 |
| RNF145 | ring finger protein 145 | 0.0365548 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0360283 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0347057 |
| NBAS | neuroblastoma amplified sequence | 0.0340438 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0336672 |
| SESN2 | sestrin 2 | 0.0325765 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0316398 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0311402 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0310073 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0309403 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0303968 |
| TMEM65 | transmembrane protein 65 | 0.0302666 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.030101 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0290985 |
| COG5 | component of oligomeric golgi complex 5 | 0.028987 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0287726 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0283317 |
| LDHA | lactate dehydrogenase A | 0.0282753 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0272249 |
| TPD52 | tumor protein D52 | 0.0271734 |
| WDR45B | WD repeat domain 45B | 0.0270394 |
| TXNIP | thioredoxin interacting protein | 0.0269376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0267869 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0265117 |
| RBM39 | RNA binding motif protein 39 | 0.0264322 |
| HELZ | helicase with zinc finger | 0.0262206 |
| RLF | rearranged L-myc fusion | 0.026004 |
| HDAC9 | histone deacetylase 9 | 0.0258771 |
| INSIG2 | insulin induced gene 2 | 0.0258286 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0255937 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253376 |
| YEATS2 | YEATS domain containing 2 | 0.0251789 |
| CDC73 | cell division cycle 73 | 0.0246787 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.024641 |
| VEGFA | vascular endothelial growth factor A | 0.0246351 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0244531 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0241933 |
| PRELID2 | PRELI domain containing 2 | 0.0238 |
| CALU | calumenin | 0.0237091 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.023609 |
| FAM13B | family with sequence similarity 13, member B | 0.0235483 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 0.0235001 |
| SUCO | SUN domain containing ossification factor | 0.0231495 |
| CLIC4 | chloride intracellular channel 4 | 0.023027 |
| RHOA | ras homolog family member A | 0.0229092 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0228254 |
| OGA | O-GlcNAcase | 0.0227368 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0225693 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0221706 |
| PREPL | prolyl endopeptidase-like | 0.022052 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0219128 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0215803 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0214351 |
| FAM13A | family with sequence similarity 13, member A | 0.0211178 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0210325 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0209448 |
| DENR | density-regulated protein | 0.020906 |
| SRP54 | signal recognition particle 54kDa | 0.020872 |
| VGLL4 | vestigial-like family member 4 | 0.0207837 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.02073 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0207244 |
| COPA | coatomer protein complex, subunit alpha | 0.0204364 |
| TMF1 | TATA element modulatory factor 1 | 0.0202846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0200438 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0198885 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0198535 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0198216 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.019746 |
| TMSB4X | thymosin beta 4, X-linked | 0.0196489 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0196328 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.019532 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0195045 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0194259 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0192855 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0192227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.100121 |
| VCL | vinculin | -0.0892863 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0871843 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0838579 |
| BMP10 | bone morphogenetic protein 10 | -0.0669278 |
| FOXP1 | forkhead box P1 | -0.0572792 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0545412 |
| RPL35A | ribosomal protein L35a | -0.0534911 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0533752 |
| RPS6 | ribosomal protein S6 | -0.048152 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.047432 |
| RPS8 | ribosomal protein S8 | -0.0459198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0412795 |
| PKM | pyruvate kinase, muscle | -0.0399701 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0399367 |
| EGFR | epidermal growth factor receptor | -0.0384376 |
| DIAPH3 | diaphanous-related formin 3 | -0.037874 |
| RPL31 | ribosomal protein L31 | -0.0376073 |
| GLI3 | GLI family zinc finger 3 | -0.0366631 |
| RPL34 | ribosomal protein L34 | -0.0350172 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0346217 |
| NBEA | neurobeachin | -0.0342713 |
| RPL12 | ribosomal protein L12 | -0.0332832 |
| S100A4 | S100 calcium binding protein A4 | -0.0326947 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322135 |
| RPL23 | ribosomal protein L23 | -0.0320731 |
| MKI67 | marker of proliferation Ki-67 | -0.0312329 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0311945 |
| RPLP0 | ribosomal protein, large, P0 | -0.0298851 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0291623 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290017 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0288123 |
| AHNAK | AHNAK nucleoprotein | -0.0281518 |
| RPL9 | ribosomal protein L9 | -0.0274732 |
| RPS24 | ribosomal protein S24 | -0.0268595 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0267642 |
| CCND1 | cyclin D1 | -0.0260398 |
| B2M | beta-2-microglobulin | -0.0259674 |
| RPL26 | ribosomal protein L26 | -0.0258592 |
| RPS27A | ribosomal protein S27a | -0.0258179 |
| RPS3 | ribosomal protein S3 | -0.0257453 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0254498 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0253752 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0245653 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0243232 |
| RPS13 | ribosomal protein S13 | -0.0240798 |
| ACTG1 | actin gamma 1 | -0.0238579 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0238562 |
| RPL19 | ribosomal protein L19 | -0.0237167 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0236771 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0234825 |
| BPTF | bromodomain PHD finger transcription factor | -0.0234683 |
| RPS21 | ribosomal protein S21 | -0.0226352 |
| RPS23 | ribosomal protein S23 | -0.0225566 |
| RPLP2 | ribosomal protein, large, P2 | -0.0218766 |
| RPL5 | ribosomal protein L5 | -0.0214048 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0207867 |
| ANLN | anillin, actin binding protein | -0.020578 |
| RPL37A | ribosomal protein L37a | -0.02049 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0203472 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0203239 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0199216 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0196183 |
| GNAS | GNAS complex locus | -0.019563 |
| RPL11 | ribosomal protein L11 | -0.0194157 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0192898 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0190136 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0188462 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0187191 |
| RPS14 | ribosomal protein S14 | -0.0186864 |
| RPS19 | ribosomal protein S19 | -0.0183553 |
| MYO5C | myosin VC | -0.018283 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0181794 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0181727 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0179136 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0178941 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.017685 |
| TPX2 | TPX2, microtubule-associated | -0.0175049 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0174171 |
| TUBA1B | tubulin, alpha 1b | -0.0172722 |
| RACK1 | receptor for activated C kinase 1 | -0.0172583 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0170815 |
| FUS | FUS RNA binding protein | -0.0167365 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0167209 |
| HMGB1 | high mobility group box 1 | -0.016717 |
| S100A10 | S100 calcium binding protein A10 | -0.0167065 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0163687 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0163437 |
| CENPF | centromere protein F, 350/400kDa | -0.016254 |
| RPS25 | ribosomal protein S25 | -0.0161171 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0159907 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0159465 |
| RPL36A | ribosomal protein L36a | -0.0157848 |
| DEK | DEK proto-oncogene | -0.0156983 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0156763 |
| MACROD2 | MACRO domain containing 2 | -0.0154256 |
| GPHN | gephyrin | -0.0154253 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0154139 |
| DGKH | diacylglycerol kinase, eta | -0.0152468 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0150954 |
