| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.221722 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.113614 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.107344 |
| CADM1 | cell adhesion molecule 1 | 0.10172 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0991075 |
| NAV2 | neuron navigator 2 | 0.0904512 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0857635 |
| SPAG9 | sperm associated antigen 9 | 0.0805278 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0792487 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0655158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.064307 |
| FN1 | fibronectin 1 | 0.0641969 |
| GOLGA4 | golgin A4 | 0.0635499 |
| MYOF | myoferlin | 0.0581475 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0558348 |
| FMNL2 | formin-like 2 | 0.0550188 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0533145 |
| OGA | O-GlcNAcase | 0.0512587 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0511715 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0509318 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0500074 |
| ZNF292 | zinc finger protein 292 | 0.0490508 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0487417 |
| SFTPA2 | surfactant protein A2 | 0.0474853 |
| SNX9 | sorting nexin 9 | 0.0474797 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0472551 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0467697 |
| NDRG1 | N-myc downstream regulated 1 | 0.045527 |
| HELZ | helicase with zinc finger | 0.0439045 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0431946 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0429034 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0425205 |
| FNIP1 | folliculin interacting protein 1 | 0.0422152 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0418056 |
| ATP13A3 | ATPase type 13A3 | 0.0410876 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0410116 |
| FLNA | filamin A, alpha | 0.0400606 |
| OPTN | optineurin | 0.0396196 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0392693 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0377607 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0373996 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0369651 |
| JMJD1C | jumonji domain containing 1C | 0.036436 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0362053 |
| WTAP | Wilms tumor 1 associated protein | 0.0356286 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0352921 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0346558 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344437 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0338634 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0337488 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0335873 |
| ADM | adrenomedullin | 0.0335273 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0330416 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0327841 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0311378 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0310778 |
| SQSTM1 | sequestosome 1 | 0.0309253 |
| CD109 | CD109 molecule | 0.0308586 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0307761 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0301228 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0299944 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.029989 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0299725 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0299589 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0295877 |
| RBM39 | RNA binding motif protein 39 | 0.0295086 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0294811 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0294549 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0292646 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0289236 |
| RND3 | Rho family GTPase 3 | 0.02817 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0280904 |
| STAG2 | stromal antigen 2 | 0.0279971 |
| FOXO3 | forkhead box O3 | 0.0279774 |
| KIF13A | kinesin family member 13A | 0.0277048 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0274022 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0273025 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0266275 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0263595 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0262465 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0259462 |
| PDE10A | phosphodiesterase 10A | 0.0258048 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0258017 |
| QKI | QKI, KH domain containing, RNA binding | 0.0252043 |
| WDR45B | WD repeat domain 45B | 0.0251505 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0250311 |
| ERBIN | erbb2 interacting protein | 0.0248979 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0248874 |
| PLIN2 | perilipin 2 | 0.0248128 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0248114 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0243779 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0243034 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0242519 |
| RYBP | RING1 and YY1 binding protein | 0.0240086 |
| CEP250 | centrosomal protein 250kDa | 0.0239182 |
| SETD5 | SET domain containing 5 | 0.0238606 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0238047 |
| CCNL1 | cyclin L1 | 0.0237273 |
| MATR3 | matrin 3 | 0.0235226 |
| PHIP | pleckstrin homology domain interacting protein | 0.0232114 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | -0.137614 |
| BICC1 | BicC family RNA binding protein 1 | -0.0969348 |
| VCL | vinculin | -0.0915683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0883233 |
| VIM | vimentin | -0.0821592 |
| TMSB10 | thymosin beta 10 | -0.0809615 |
| HLA-B | major histocompatibility complex, class I, B | -0.0789126 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0758368 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0757477 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0646507 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0610132 |
| FRMD4A | FERM domain containing 4A | -0.0602666 |
| MT2A | metallothionein 2A | -0.0503645 |
| HMGA2 | high mobility group AT-hook 2 | -0.0491467 |
| KYNU | kynureninase | -0.0473011 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0424555 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0410201 |
| RPS12 | ribosomal protein S12 | -0.0368361 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0359809 |
| RPLP2 | ribosomal protein, large, P2 | -0.0354788 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0350124 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0346476 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0339818 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0338172 |
| RIGI | RNA sensor RIG-I | -0.0337864 |
| RPL37A | ribosomal protein L37a | -0.0336532 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0321464 |
| RPS3 | ribosomal protein S3 | -0.0309773 |
| SMAD3 | SMAD family member 3 | -0.0307512 |
| NABP1 | nucleic acid binding protein 1 | -0.0306347 |
| PALLD | palladin, cytoskeletal associated protein | -0.030421 |
| RPL36A | ribosomal protein L36a | -0.0302604 |
| HLA-A | major histocompatibility complex, class I, A | -0.0298603 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.029675 |
| EHBP1 | EH domain binding protein 1 | -0.0291281 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0289021 |
| THBS1 | thrombospondin 1 | -0.0276208 |
| FAM20C | family with sequence similarity 20, member C | -0.0274748 |
| VCAN | versican | -0.0273076 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0272088 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0268494 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265538 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0259186 |
| RPLP1 | ribosomal protein, large, P1 | -0.025706 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0243413 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0240389 |
| OSMR | oncostatin M receptor | -0.0236337 |
| RPS8 | ribosomal protein S8 | -0.0234647 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.023361 |
| RPL36 | ribosomal protein L36 | -0.0232258 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0229382 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.022546 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0224539 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.022333 |
| B2M | beta-2-microglobulin | -0.0219708 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0219128 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0212999 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0207799 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0207248 |
| RAI14 | retinoic acid induced 14 | -0.0201028 |
| RPL12 | ribosomal protein L12 | -0.0201004 |
| GPC6 | glypican 6 | -0.0200261 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0198437 |
| FTL | ferritin, light polypeptide | -0.0197807 |
| PMP22 | peripheral myelin protein 22 | -0.0197551 |
| RPS19 | ribosomal protein S19 | -0.0194821 |
| HDAC8 | histone deacetylase 8 | -0.0194815 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0191809 |
| TPM1 | tropomyosin 1 (alpha) | -0.0186575 |
| CALR | calreticulin | -0.0185861 |
| RPL19 | ribosomal protein L19 | -0.0184401 |
| RPL28 | ribosomal protein L28 | -0.0181258 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0180134 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.017927 |
| RPS17 | ribosomal protein S17 | -0.0176737 |
| RPS29 | ribosomal protein S29 | -0.01749 |
| TRIM55 | tripartite motif containing 55 | -0.0174062 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0173664 |
| RNF213 | ring finger protein 213 | -0.0172129 |
| S100A9 | S100 calcium binding protein A9 | -0.0171076 |
| VMP1 | vacuole membrane protein 1 | -0.0170804 |
| RPS27A | ribosomal protein S27a | -0.0169212 |
| TGM2 | transglutaminase 2 | -0.0168959 |
| RPL9 | ribosomal protein L9 | -0.0167342 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0167054 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0164251 |
| RPL13A | ribosomal protein L13a | -0.0162387 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0162126 |
| HLA-E | major histocompatibility complex, class I, E | -0.0161748 |
| STK17A | serine/threonine kinase 17a | -0.0161155 |
| RPL32 | ribosomal protein L32 | -0.0160732 |
| RPL35 | ribosomal protein L35 | -0.0160135 |
| RPS23 | ribosomal protein S23 | -0.015998 |
| MX2 | MX dynamin-like GTPase 2 | -0.0159948 |
| RPL26 | ribosomal protein L26 | -0.01589 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0158345 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.015691 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0156507 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0155842 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0154354 |
