| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.139699 |
| TXNRD1 | thioredoxin reductase 1 | 0.0796834 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0685377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0670631 |
| GOLGA4 | golgin A4 | 0.0657255 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0647386 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0632446 |
| SPAG9 | sperm associated antigen 9 | 0.0538585 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0535791 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0521538 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.046747 |
| RBM39 | RNA binding motif protein 39 | 0.0463953 |
| YAP1 | Yes-associated protein 1 | 0.0427984 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0424054 |
| RTN4 | reticulon 4 | 0.041214 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0409776 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0392524 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0387567 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0378504 |
| SET | SET nuclear proto-oncogene | 0.0377423 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0363472 |
| CD44 | CD44 molecule (Indian blood group) | 0.0359237 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0346957 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0335633 |
| ANXA2 | annexin A2 | 0.0325635 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0322125 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320627 |
| FMNL2 | formin-like 2 | 0.0318368 |
| MATR3 | matrin 3 | 0.0317319 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0315109 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.031404 |
| QKI | QKI, KH domain containing, RNA binding | 0.0313288 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312379 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0311073 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0308534 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0298555 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0294649 |
| CLTC | clathrin, heavy chain (Hc) | 0.0287189 |
| SEPTIN2 | septin 2 | 0.0284252 |
| KIF5B | kinesin family member 5B | 0.0283674 |
| ANLN | anillin, actin binding protein | 0.0276106 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0273102 |
| CRY1 | cryptochrome circadian clock 1 | 0.0272924 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0271458 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0270695 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0265943 |
| HSPA8 | heat shock 70kDa protein 8 | 0.026452 |
| RNF145 | ring finger protein 145 | 0.0259766 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0259681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255241 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0254581 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0254162 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.025382 |
| YBX3 | Y box binding protein 3 | 0.0253514 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0253359 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0248826 |
| AHNAK | AHNAK nucleoprotein | 0.0248679 |
| SMC4 | structural maintenance of chromosomes 4 | 0.024647 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0245183 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0245015 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0243806 |
| NKTR | natural killer cell triggering receptor | 0.0238975 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0236527 |
| MAP1B | microtubule-associated protein 1B | 0.0234241 |
| ZNF292 | zinc finger protein 292 | 0.0231141 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0230371 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0230114 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0226052 |
| ZFP91 | ZFP91 zinc finger protein | 0.0225943 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0224832 |
| SQSTM1 | sequestosome 1 | 0.0223901 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0222168 |
| FLNA | filamin A, alpha | 0.0221778 |
| CENPF | centromere protein F, 350/400kDa | 0.0220706 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0220161 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0218699 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0218232 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.021756 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0217364 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0216939 |
| PAPOLA | poly(A) polymerase alpha | 0.0216643 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0214233 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0213554 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0212216 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0208376 |
| DIAPH3 | diaphanous-related formin 3 | 0.020695 |
| TFG | TRK-fused gene | 0.0206874 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0206341 |
| ITSN2 | intersectin 2 | 0.0205934 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.020399 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0201666 |
| SETD5 | SET domain containing 5 | 0.0200399 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0200205 |
| BRD2 | bromodomain containing 2 | 0.019666 |
| JMJD1C | jumonji domain containing 1C | 0.0195806 |
| ERBIN | erbb2 interacting protein | 0.0193775 |
| TPX2 | TPX2, microtubule-associated | 0.0193593 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0191805 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0189482 |
| YY1 | YY1 transcription factor | 0.0189475 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0630874 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0514189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0490809 |
| HMGA2 | high mobility group AT-hook 2 | -0.0441142 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.043414 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0421294 |
| INTS6 | integrator complex subunit 6 | -0.0420971 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0401588 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0392271 |
| PTMA | prothymosin, alpha | -0.0390898 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0377568 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0363568 |
| LDHA | lactate dehydrogenase A | -0.0354208 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0331531 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0323987 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0312127 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0305819 |
| RIGI | RNA sensor RIG-I | -0.0298784 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0292189 |
| RAI14 | retinoic acid induced 14 | -0.0275554 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265183 |
| EGR1 | early growth response 1 | -0.0262298 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0260784 |
| TMSB10 | thymosin beta 10 | -0.02482 |
| VCL | vinculin | -0.0247441 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0244764 |
| AOPEP | aminopeptidase O (putative) | -0.0240215 |
| RPL35A | ribosomal protein L35a | -0.0237863 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0236959 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0233413 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0230589 |
| ANGPTL4 | angiopoietin-like 4 | -0.0229043 |
| SMYD3 | SET and MYND domain containing 3 | -0.0228819 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0224452 |
| SCFD1 | sec1 family domain containing 1 | -0.0222942 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0221923 |
| RPL31 | ribosomal protein L31 | -0.0221324 |
| FMN1 | formin 1 | -0.0219373 |
| RNF213 | ring finger protein 213 | -0.0217076 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0212979 |
| RAD51B | RAD51 paralog B | -0.0208226 |
| ZNF609 | zinc finger protein 609 | -0.0207519 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0206286 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0205135 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0204463 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0203883 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0203581 |
| GPC5 | glypican 5 | -0.0202922 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0201695 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0200393 |
| RPL36 | ribosomal protein L36 | -0.0196519 |
| IGF2 | insulin-like growth factor 2 | -0.0196445 |
| SETX | senataxin | -0.0194864 |
| PCNX4 | pecanex 4 | -0.0194028 |
| PRELID2 | PRELI domain containing 2 | -0.0193243 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.0193177 |
| GNAS | GNAS complex locus | -0.0192841 |
| HLA-B | major histocompatibility complex, class I, B | -0.0190633 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.018909 |
| OSMR | oncostatin M receptor | -0.0188857 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0187842 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0182566 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0181942 |
| FN1 | fibronectin 1 | -0.0180397 |
| PRKCA | protein kinase C, alpha | -0.0178865 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0176213 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0175068 |
| HLA-A | major histocompatibility complex, class I, A | -0.0171491 |
| SKI | SKI proto-oncogene | -0.0168564 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0168139 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0167867 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0165031 |
| KLHL5 | kelch-like family member 5 | -0.0159111 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0158069 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0156325 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0155306 |
| ETV6 | ets variant 6 | -0.0153976 |
| S100A9 | S100 calcium binding protein A9 | -0.0153787 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0153203 |
| EGFR | epidermal growth factor receptor | -0.0152723 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0152408 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0151921 |
| RPL37 | ribosomal protein L37 | -0.0151644 |
| NF1 | neurofibromin 1 | -0.0151552 |
| CCNH | cyclin H | -0.015083 |
| TRIM5 | tripartite motif containing 5 | -0.0148876 |
| ABR | active BCR-related | -0.0148522 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.01485 |
| GLRX | glutaredoxin (thioltransferase) | -0.0148227 |
| TMED7-TICAM2 | TMED7-TICAM2 readthrough | -0.0148021 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -0.0147974 |
| JAZF1 | JAZF zinc finger 1 | -0.014712 |
| IFI44 | interferon-induced protein 44 | -0.0146646 |
| RCOR1 | REST corepressor 1 | -0.0146369 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0144196 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0142417 |
| FOXO3 | forkhead box O3 | -0.0142269 |
| HDAC9 | histone deacetylase 9 | -0.014217 |
| H3-3B | H3.3 histone B | -0.01417 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0141565 |
