| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.228205 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0970389 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0720193 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0716688 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0678913 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0622322 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0610351 |
| RNF145 | ring finger protein 145 | 0.0567398 |
| CD109 | CD109 molecule | 0.0557243 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0517619 |
| GOLGA4 | golgin A4 | 0.0510033 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0485438 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0472303 |
| SPAG9 | sperm associated antigen 9 | 0.0463864 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0462911 |
| SUCO | SUN domain containing ossification factor | 0.0419644 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0417537 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0406471 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0399753 |
| TXNRD1 | thioredoxin reductase 1 | 0.0392705 |
| FAT1 | FAT atypical cadherin 1 | 0.038731 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0383008 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0367626 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0363479 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0362994 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0357867 |
| RBM39 | RNA binding motif protein 39 | 0.0350699 |
| PTMA | prothymosin, alpha | 0.0349279 |
| NUP58 | nucleoporin 58 | 0.0347852 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0347735 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0344544 |
| QKI | QKI, KH domain containing, RNA binding | 0.034223 |
| COPA | coatomer protein complex, subunit alpha | 0.0339758 |
| OGA | O-GlcNAcase | 0.0336173 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335324 |
| VIM | vimentin | 0.0333659 |
| NEK7 | NIMA-related kinase 7 | 0.0326904 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0326612 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0323484 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.0320424 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0315704 |
| RLF | rearranged L-myc fusion | 0.0314688 |
| RTN4 | reticulon 4 | 0.0312802 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0303431 |
| XPO1 | exportin 1 | 0.0301943 |
| CENPF | centromere protein F, 350/400kDa | 0.0298162 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0296021 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0294778 |
| WDR43 | WD repeat domain 43 | 0.0294149 |
| NOP58 | NOP58 ribonucleoprotein | 0.0288215 |
| WDR45B | WD repeat domain 45B | 0.028778 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0286939 |
| MATR3 | matrin 3 | 0.0286426 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0284576 |
| YME1L1 | YME1-like 1 ATPase | 0.0282783 |
| EREG | epiregulin | 0.0282559 |
| SQSTM1 | sequestosome 1 | 0.0281394 |
| SNX9 | sorting nexin 9 | 0.0280523 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279935 |
| TFG | TRK-fused gene | 0.0275067 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0273163 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.027306 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0271252 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0269758 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0269062 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0267609 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0266324 |
| APP | amyloid beta (A4) precursor protein | 0.026518 |
| FOSL1 | FOS-like antigen 1 | 0.0264449 |
| ANXA5 | annexin A5 | 0.0262975 |
| TPR | translocated promoter region, nuclear basket protein | 0.0259647 |
| COG5 | component of oligomeric golgi complex 5 | 0.0258671 |
| JMJD1C | jumonji domain containing 1C | 0.0258214 |
| RPS6 | ribosomal protein S6 | 0.0257903 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.025774 |
| RHEB | Ras homolog enriched in brain | 0.025721 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0254007 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0253563 |
| ERBIN | erbb2 interacting protein | 0.0253211 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0253161 |
| SEPTIN7 | septin 7 | 0.0247752 |
| HELZ | helicase with zinc finger | 0.0247581 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0246361 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0244177 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0243262 |
| ANLN | anillin, actin binding protein | 0.0242892 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0241148 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0240611 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0240155 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0239601 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0238908 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0238244 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0237694 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0237434 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0237384 |
| DUSP5 | dual specificity phosphatase 5 | 0.0235389 |
| RBM25 | RNA binding motif protein 25 | 0.0235321 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232932 |
| SFTPA2 | surfactant protein A2 | 0.0232437 |
| CLINT1 | clathrin interactor 1 | 0.0232081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.266551 |
| FN1 | fibronectin 1 | -0.216423 |
| HMGA2 | high mobility group AT-hook 2 | -0.170237 |
| ASPH | aspartate beta-hydroxylase | -0.0955663 |
| GLIS3 | GLIS family zinc finger 3 | -0.085895 |
| EFNA5 | ephrin-A5 | -0.0721371 |
| VCL | vinculin | -0.0677964 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0674597 |
| ITGA1 | integrin, alpha 1 | -0.0641405 |
| EXT1 | exostosin glycosyltransferase 1 | -0.06256 |
| AEBP2 | AE binding protein 2 | -0.0558825 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0523859 |
| RAI14 | retinoic acid induced 14 | -0.0498041 |
| INTS6 | integrator complex subunit 6 | -0.0494073 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0415482 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0408488 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.040702 |
| TMSB10 | thymosin beta 10 | -0.0403053 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0387011 |
| SYT1 | synaptotagmin I | -0.0383131 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0379549 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0356844 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0349598 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0347318 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0338071 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0328228 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0320112 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.031632 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0303846 |
| LOXL2 | lysyl oxidase-like 2 | -0.0303476 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0303136 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0288719 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0287611 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0280148 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0275837 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0275236 |
| PALLD | palladin, cytoskeletal associated protein | -0.0274811 |
| RAD51B | RAD51 paralog B | -0.0274091 |
| TENM4 | teneurin transmembrane protein 4 | -0.0271524 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0259449 |
| LRRC23 | leucine rich repeat containing 23 | -0.0258457 |
| TGFA | transforming growth factor, alpha | -0.0255647 |
| PRKCA | protein kinase C, alpha | -0.0254229 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0247638 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246667 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0245253 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0243956 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0238379 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0236322 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0228845 |
| TNS3 | tensin 3 | -0.0228095 |
| OXR1 | oxidation resistance 1 | -0.0227215 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0227165 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0226338 |
| RNF213 | ring finger protein 213 | -0.0225123 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0223476 |
| FAM20C | family with sequence similarity 20, member C | -0.0220498 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0218247 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0215881 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0212702 |
| NTN4 | netrin 4 | -0.0209722 |
| IFI44L | interferon-induced protein 44-like | -0.0206096 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0204186 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0201676 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0199879 |
| HLA-B | major histocompatibility complex, class I, B | -0.0198096 |
| NAV1 | neuron navigator 1 | -0.0194302 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0193853 |
| RASAL2 | RAS protein activator like 2 | -0.0192652 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0190195 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0187251 |
| VEGFC | vascular endothelial growth factor C | -0.0186786 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0186234 |
| PRELID2 | PRELI domain containing 2 | -0.0184307 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.018329 |
| CUX1 | cut-like homeobox 1 | -0.0180193 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0179732 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0179604 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0177528 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0177024 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0172585 |
| NRP1 | neuropilin 1 | -0.0169871 |
| ETV6 | ets variant 6 | -0.0169219 |
| MCL1 | myeloid cell leukemia 1 | -0.0167342 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0166702 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0162291 |
| CCDC138 | coiled-coil domain containing 138 | -0.0160443 |
| NBEA | neurobeachin | -0.0159995 |
| SUMF1 | sulfatase modifying factor 1 | -0.0158812 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0158514 |
| EXOC4 | exocyst complex component 4 | -0.0157432 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0157172 |
| TGFB1 | transforming growth factor, beta 1 | -0.0154076 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0153177 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0152794 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0152462 |
| MLPH | melanophilin | -0.0152153 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.015209 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0151839 |
| RANBP17 | RAN binding protein 17 | -0.0150319 |
