| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0773172 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0599724 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.052943 |
| KRT18 | keratin 18, type I | 0.0400386 |
| CCNL1 | cyclin L1 | 0.0371517 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0341497 |
| CCND1 | cyclin D1 | 0.0329329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320765 |
| FLNA | filamin A, alpha | 0.0319058 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0314532 |
| PLEC | plectin | 0.0312305 |
| PCBP2 | poly(rC) binding protein 2 | 0.0258378 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0253083 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0248015 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247707 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0243939 |
| POTEF | POTE ankyrin domain family, member F | 0.0241505 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.023819 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0236616 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0228996 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.022706 |
| NCKAP1 | NCK-associated protein 1 | 0.0225882 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0216041 |
| MYO10 | myosin X | 0.0214962 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0212831 |
| MED13L | mediator complex subunit 13-like | 0.020491 |
| YAP1 | Yes-associated protein 1 | 0.0204036 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0202004 |
| ATL2 | atlastin GTPase 2 | 0.020083 |
| KRT8 | keratin 8, type II | 0.0195545 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0190961 |
| MTMR3 | myotubularin related protein 3 | 0.0190322 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0186104 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0184975 |
| TOP1 | topoisomerase (DNA) I | 0.0184185 |
| BRD2 | bromodomain containing 2 | 0.018002 |
| WDR43 | WD repeat domain 43 | 0.0179634 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0178254 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0175229 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0173087 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0168371 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0167807 |
| SUCO | SUN domain containing ossification factor | 0.01678 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0164771 |
| TPM3 | tropomyosin 3 | 0.0164358 |
| DIAPH1 | diaphanous-related formin 1 | 0.0163184 |
| PAPOLA | poly(A) polymerase alpha | 0.0162912 |
| CUL3 | cullin 3 | 0.016096 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.015787 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0149812 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0148117 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0147936 |
| ITGA6 | integrin, alpha 6 | 0.0145564 |
| TFG | TRK-fused gene | 0.0144102 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0142062 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0140058 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0139656 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0139507 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0139197 |
| TXNRD1 | thioredoxin reductase 1 | 0.0138648 |
| RPL3 | ribosomal protein L3 | 0.013859 |
| USP3 | ubiquitin specific peptidase 3 | 0.0135912 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0135765 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.013574 |
| ECT2 | epithelial cell transforming 2 | 0.0135654 |
| CRY1 | cryptochrome circadian clock 1 | 0.0135197 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0135113 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0133947 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0133385 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0131876 |
| SETD5 | SET domain containing 5 | 0.0128515 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0128479 |
| DHFR | dihydrofolate reductase | 0.0128445 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0128315 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0127326 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0127314 |
| TCERG1 | transcription elongation regulator 1 | 0.0126559 |
| SIK3 | SIK family kinase 3 | 0.012654 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0125832 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.0125649 |
| HDGF | hepatoma-derived growth factor | 0.0124615 |
| TMEM41B | transmembrane protein 41B | 0.0122944 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0120888 |
| DSPP | dentin sialophosphoprotein | 0.0120582 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0120538 |
| SNX9 | sorting nexin 9 | 0.0120227 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0119552 |
| ANXA2 | annexin A2 | 0.011893 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0118607 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0118453 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0117736 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0117626 |
| GOLGA4 | golgin A4 | 0.0117048 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0116046 |
| XPO1 | exportin 1 | 0.0116004 |
| PNN | pinin, desmosome associated protein | 0.0115404 |
| RCOR1 | REST corepressor 1 | 0.0115144 |
| TJP1 | tight junction protein 1 | 0.0114348 |
| MKI67 | marker of proliferation Ki-67 | 0.0113864 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0113773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.140689 |
| PTMA | prothymosin, alpha | -0.114305 |
| TMSB10 | thymosin beta 10 | -0.0741048 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.071111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0601623 |
| RPL35A | ribosomal protein L35a | -0.0568094 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.04889 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0483417 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.044482 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0442294 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0419313 |
| RPS21 | ribosomal protein S21 | -0.0409902 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0404028 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0399941 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0381809 |
| PRELID2 | PRELI domain containing 2 | -0.036754 |
| B2M | beta-2-microglobulin | -0.0362064 |
| RPL31 | ribosomal protein L31 | -0.0342918 |
| RPL23 | ribosomal protein L23 | -0.0341215 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326364 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0322698 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0315599 |
| FRMD5 | FERM domain containing 5 | -0.0306817 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0302185 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0299714 |
| LDHA | lactate dehydrogenase A | -0.0297758 |
| RPLP2 | ribosomal protein, large, P2 | -0.0296629 |
| SERINC5 | serine incorporator 5 | -0.0295985 |
| RPL37A | ribosomal protein L37a | -0.0294454 |
| EPCAM | epithelial cell adhesion molecule | -0.0292848 |
| PGK1 | phosphoglycerate kinase 1 | -0.0291765 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0289708 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0285422 |
| EHBP1 | EH domain binding protein 1 | -0.0276407 |
| ZNRF3 | zinc and ring finger 3 | -0.0273941 |
| RPS19 | ribosomal protein S19 | -0.0270509 |
| RPS27A | ribosomal protein S27a | -0.0268405 |
| RNF43 | ring finger protein 43 | -0.0267723 |
| RPL28 | ribosomal protein L28 | -0.0263089 |
| BBX | bobby sox homolog (Drosophila) | -0.0257728 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0257056 |
| RPS13 | ribosomal protein S13 | -0.0247469 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0238734 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.023872 |
| NDRG1 | N-myc downstream regulated 1 | -0.0234981 |
| IER3 | immediate early response 3 | -0.0233221 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0232645 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0230918 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0226982 |
| RPL18 | ribosomal protein L18 | -0.0223702 |
| RPL12 | ribosomal protein L12 | -0.0219172 |
| RNF213 | ring finger protein 213 | -0.0218806 |
| RPS29 | ribosomal protein S29 | -0.0218373 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0217331 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0217066 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0214992 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0214537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.021416 |
| RAD51B | RAD51 paralog B | -0.0211147 |
| RPS11 | ribosomal protein S11 | -0.021061 |
| RPS3 | ribosomal protein S3 | -0.0209931 |
| RPS8 | ribosomal protein S8 | -0.0209805 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0208417 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0207346 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.020521 |
| NFIA | nuclear factor I/A | -0.0202629 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0199226 |
| RPL8 | ribosomal protein L8 | -0.019805 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0197536 |
| SMYD3 | SET and MYND domain containing 3 | -0.0197056 |
| EZR | ezrin | -0.0191107 |
| FHIT | fragile histidine triad | -0.0190647 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0188294 |
| RPL7A | ribosomal protein L7a | -0.0185938 |
| ACTN4 | actinin, alpha 4 | -0.0185401 |
| RPL34 | ribosomal protein L34 | -0.0185216 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0183951 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0183775 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0182766 |
| RPL37 | ribosomal protein L37 | -0.0182609 |
| GNAS | GNAS complex locus | -0.0182334 |
| RPS24 | ribosomal protein S24 | -0.0181185 |
| RPL32 | ribosomal protein L32 | -0.018098 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0180765 |
| RPL36 | ribosomal protein L36 | -0.0179376 |
| EXOC4 | exocyst complex component 4 | -0.0179118 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0177863 |
| TXNIP | thioredoxin interacting protein | -0.0176877 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0172149 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0169585 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0168692 |
| HOXB3 | homeobox B3 | -0.0168226 |
| HM13 | histocompatibility (minor) 13 | -0.0167692 |
| NAV2 | neuron navigator 2 | -0.0164395 |
| HLA-B | major histocompatibility complex, class I, B | -0.0164119 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0161343 |
| RPL26 | ribosomal protein L26 | -0.0161142 |
| PKP4 | plakophilin 4 | -0.0160531 |
| TPM4 | tropomyosin 4 | -0.0160529 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.016028 |
