| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | 0.183074 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.144886 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0914568 |
| ANXA1 | annexin A1 | 0.0869628 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0814208 |
| TXNRD1 | thioredoxin reductase 1 | 0.0788193 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0775737 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0671712 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0669015 |
| IER3 | immediate early response 3 | 0.065378 |
| EZR | ezrin | 0.0652912 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.06191 |
| RNF43 | ring finger protein 43 | 0.0599406 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0585661 |
| AREG | amphiregulin | 0.0578304 |
| OXR1 | oxidation resistance 1 | 0.0568766 |
| RUNX2 | runt-related transcription factor 2 | 0.0538802 |
| DSPP | dentin sialophosphoprotein | 0.0537363 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0535763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0529324 |
| EREG | epiregulin | 0.0523795 |
| LMO7 | LIM domain 7 | 0.0522683 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0515271 |
| LAMB3 | laminin, beta 3 | 0.0512617 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0492338 |
| TOP1 | topoisomerase (DNA) I | 0.0481606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0465524 |
| AHNAK | AHNAK nucleoprotein | 0.0461077 |
| GOLGA4 | golgin A4 | 0.0454429 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.042989 |
| LAMC2 | laminin, gamma 2 | 0.0428 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0426623 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0424871 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0420289 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0419356 |
| SQSTM1 | sequestosome 1 | 0.0415145 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0414725 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0410083 |
| AXIN2 | axin 2 | 0.0401091 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.037387 |
| FAT1 | FAT atypical cadherin 1 | 0.037012 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0366606 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0366116 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0360018 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0359038 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.035596 |
| ANXA2 | annexin A2 | 0.0353288 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0347609 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0344918 |
| ZNRF3 | zinc and ring finger 3 | 0.0340978 |
| WDR43 | WD repeat domain 43 | 0.0338312 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0336841 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0329591 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0324327 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0323703 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0322833 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0321401 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0317247 |
| RPS4X | ribosomal protein S4, X-linked | 0.0315128 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0309588 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304562 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0303931 |
| CLTC | clathrin, heavy chain (Hc) | 0.0299378 |
| ANLN | anillin, actin binding protein | 0.0298524 |
| ZNF292 | zinc finger protein 292 | 0.0298098 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0296483 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0291423 |
| SNX9 | sorting nexin 9 | 0.0287868 |
| SLMAP | sarcolemma associated protein | 0.0281739 |
| YAP1 | Yes-associated protein 1 | 0.0281114 |
| USP3 | ubiquitin specific peptidase 3 | 0.0277552 |
| APP | amyloid beta (A4) precursor protein | 0.027567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0273751 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0273637 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0272999 |
| RBM39 | RNA binding motif protein 39 | 0.027265 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0268839 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0267245 |
| NOP58 | NOP58 ribonucleoprotein | 0.0266692 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0265801 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0262842 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0260997 |
| YBX1 | Y box binding protein 1 | 0.0260849 |
| KITLG | KIT ligand | 0.0258679 |
| RPL21 | ribosomal protein L21 | 0.0256532 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0256315 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0255933 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0254171 |
| XPO1 | exportin 1 | 0.02534 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0253125 |
| OGA | O-GlcNAcase | 0.0249921 |
| COG5 | component of oligomeric golgi complex 5 | 0.024933 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0248392 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0247215 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0244541 |
| CCNL1 | cyclin L1 | 0.0243398 |
| TFRC | transferrin receptor | 0.0243374 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0242634 |
| SLTM | SAFB-like, transcription modulator | 0.0242422 |
| CD2AP | CD2-associated protein | 0.024241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.112074 |
| RPL35A | ribosomal protein L35a | -0.0876978 |
| RCOR1 | REST corepressor 1 | -0.0549388 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0522799 |
| EGR1 | early growth response 1 | -0.0522191 |
| RPL31 | ribosomal protein L31 | -0.0471566 |
| FTL | ferritin, light polypeptide | -0.0462641 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0425084 |
| VCL | vinculin | -0.0417174 |
| LAMA4 | laminin, alpha 4 | -0.036054 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0352977 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0346657 |
| RPS6 | ribosomal protein S6 | -0.0346254 |
| RPS25 | ribosomal protein S25 | -0.0338497 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0330893 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329306 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.032089 |
| RPS29 | ribosomal protein S29 | -0.0313782 |
| RPS8 | ribosomal protein S8 | -0.0291202 |
| RPL9 | ribosomal protein L9 | -0.0286111 |
| RPS23 | ribosomal protein S23 | -0.0284193 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0276059 |
| RPL34 | ribosomal protein L34 | -0.0275335 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027394 |
| HMGA2 | high mobility group AT-hook 2 | -0.0273549 |
| HLA-A | major histocompatibility complex, class I, A | -0.0272142 |
| FHIT | fragile histidine triad | -0.0271606 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0263565 |
| RPS13 | ribosomal protein S13 | -0.0252698 |
| CUX1 | cut-like homeobox 1 | -0.025064 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0250168 |
| CMIP | c-Maf inducing protein | -0.0247779 |
| PTMA | prothymosin, alpha | -0.0237225 |
| GPC5 | glypican 5 | -0.0232763 |
| UBAP2 | ubiquitin associated protein 2 | -0.0228573 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0222803 |
| ABR | active BCR-related | -0.0220596 |
| BPTF | bromodomain PHD finger transcription factor | -0.0209788 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0209278 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0202918 |
| RPS14 | ribosomal protein S14 | -0.0201092 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0193561 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0192706 |
| POTEF | POTE ankyrin domain family, member F | -0.0191572 |
| RPS27A | ribosomal protein S27a | -0.01915 |
| TMSB10 | thymosin beta 10 | -0.0190077 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0189801 |
| GDF15 | growth differentiation factor 15 | -0.0189314 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0185405 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0184767 |
| SCFD1 | sec1 family domain containing 1 | -0.0180307 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0179031 |
| HLA-B | major histocompatibility complex, class I, B | -0.0178532 |
| VIM | vimentin | -0.0173532 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0173475 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0171427 |
| RPL37A | ribosomal protein L37a | -0.0168495 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0166497 |
| CDK13 | cyclin-dependent kinase 13 | -0.0158034 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0155333 |
| RPL15 | ribosomal protein L15 | -0.0154849 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0153775 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0150808 |
| RPL23 | ribosomal protein L23 | -0.0150571 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0149226 |
| HDAC8 | histone deacetylase 8 | -0.0148093 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0147087 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0147028 |
| PHF14 | PHD finger protein 14 | -0.014502 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0144766 |
| SMYD3 | SET and MYND domain containing 3 | -0.0143333 |
| LSMEM2 | leucine-rich single-pass membrane protein 2 | -0.0143036 |
| SEPTIN9 | septin 9 | -0.0142825 |
| RPL27 | ribosomal protein L27 | -0.0141959 |
| CFAP161 | cilia and flagella associated protein 161 | -0.014099 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0140931 |
| MTAP | methylthioadenosine phosphorylase | -0.0140524 |
| UBC | ubiquitin C | -0.0138367 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0136823 |
| RPS21 | ribosomal protein S21 | -0.0136058 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0134287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0132999 |
| GLCCI1 | glucocorticoid induced 1 | -0.0132069 |
| INTS6 | integrator complex subunit 6 | -0.0131815 |
| KLK10 | kallikrein-related peptidase 10 | -0.0131744 |
| COMMD10 | COMM domain containing 10 | -0.013069 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0130361 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0129714 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0127973 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.0127179 |
| RPL5 | ribosomal protein L5 | -0.0127057 |
| TENM3 | teneurin transmembrane protein 3 | -0.0126612 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.012619 |
| HM13 | histocompatibility (minor) 13 | -0.0125318 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0124796 |
| PCNX4 | pecanex 4 | -0.0124439 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0123968 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0123812 |
| CLCF1 | cardiotrophin-like cytokine factor 1 | -0.0122759 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0121469 |
