| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.233817 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.149345 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.12284 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.115095 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.11296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103189 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0978202 |
| FAM13A | family with sequence similarity 13, member A | 0.0917113 |
| SPAG9 | sperm associated antigen 9 | 0.0864998 |
| GOLGA4 | golgin A4 | 0.0838894 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0838673 |
| CALU | calumenin | 0.082512 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0755877 |
| MMP1 | matrix metallopeptidase 1 | 0.0703061 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0693302 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0682511 |
| MMP12 | matrix metallopeptidase 12 | 0.0638083 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0601653 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0599378 |
| NDRG1 | N-myc downstream regulated 1 | 0.0585603 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0575409 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0572108 |
| DST | dystonin | 0.0559163 |
| FMNL2 | formin-like 2 | 0.0557754 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0555218 |
| CANX | calnexin | 0.0545882 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0534854 |
| NAV2 | neuron navigator 2 | 0.0521605 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0511098 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.051005 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0498153 |
| VIM | vimentin | 0.0496637 |
| ADM | adrenomedullin | 0.0489641 |
| IER3 | immediate early response 3 | 0.0472758 |
| RTN4 | reticulon 4 | 0.0469673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0464524 |
| ANXA5 | annexin A5 | 0.0461857 |
| OGA | O-GlcNAcase | 0.0457051 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0450102 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0446283 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0446045 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0442996 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0437303 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0425279 |
| ZNF292 | zinc finger protein 292 | 0.0421963 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0421134 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0420103 |
| LDHA | lactate dehydrogenase A | 0.0414528 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0414124 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.041394 |
| PGK1 | phosphoglycerate kinase 1 | 0.0398517 |
| RND3 | Rho family GTPase 3 | 0.0395981 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.039567 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0395428 |
| FNIP1 | folliculin interacting protein 1 | 0.0392797 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0384878 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0379578 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0378534 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0376908 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0362344 |
| SUCO | SUN domain containing ossification factor | 0.0361801 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0360595 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.035915 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0355877 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0352206 |
| CENPF | centromere protein F, 350/400kDa | 0.0350257 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0349476 |
| HELZ | helicase with zinc finger | 0.0347876 |
| CALR | calreticulin | 0.0347787 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0345673 |
| RNF145 | ring finger protein 145 | 0.0343356 |
| HDLBP | high density lipoprotein binding protein | 0.0341401 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0338592 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0337642 |
| PTK2 | protein tyrosine kinase 2 | 0.0330648 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0329176 |
| XPO1 | exportin 1 | 0.0328282 |
| GPHN | gephyrin | 0.0326179 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0326059 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0325242 |
| TNPO1 | transportin 1 | 0.0324462 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0323126 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0322942 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0321122 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0319276 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0318528 |
| FLNA | filamin A, alpha | 0.031517 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0314439 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0312216 |
| SQSTM1 | sequestosome 1 | 0.0310372 |
| NUP58 | nucleoporin 58 | 0.0309658 |
| ENO1 | enolase 1, (alpha) | 0.0309401 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0309124 |
| AHNAK | AHNAK nucleoprotein | 0.0308689 |
| APP | amyloid beta (A4) precursor protein | 0.0308366 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0307314 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0306864 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0306861 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0305452 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0300782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179641 |
| HMGA2 | high mobility group AT-hook 2 | -0.0930533 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0821224 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0812232 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0760434 |
| COL5A3 | collagen, type V, alpha 3 | -0.0707756 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.064628 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0629761 |
| VCL | vinculin | -0.0568295 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0517706 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0503872 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0483653 |
| TMSB10 | thymosin beta 10 | -0.045987 |
| EGFR | epidermal growth factor receptor | -0.0458208 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0453265 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0451945 |
| VMP1 | vacuole membrane protein 1 | -0.0429344 |
| FRMD4A | FERM domain containing 4A | -0.0420103 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0378391 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0370003 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0353268 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0335779 |
| STC1 | stanniocalcin 1 | -0.0332645 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0327071 |
| GLIS3 | GLIS family zinc finger 3 | -0.0320473 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0313422 |
| DIAPH2 | diaphanous-related formin 2 | -0.0311528 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0309518 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0302949 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0285108 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0284472 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0282434 |
| CCDC102B | coiled-coil domain containing 102B | -0.027786 |
| EMP1 | epithelial membrane protein 1 | -0.0274868 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.027249 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0269873 |
| RAI14 | retinoic acid induced 14 | -0.0257349 |
| CYTH3 | cytohesin 3 | -0.0253251 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0252967 |
| RSU1 | Ras suppressor protein 1 | -0.0251292 |
| CLMP | CXADR-like membrane protein | -0.0251244 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0248005 |
| OXR1 | oxidation resistance 1 | -0.024595 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0235183 |
| EGR1 | early growth response 1 | -0.0226235 |
| PRRX1 | paired related homeobox 1 | -0.0224414 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0211722 |
| KIAA1549L | KIAA1549-like | -0.020443 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0200479 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.0195847 |
| NAV1 | neuron navigator 1 | -0.0189872 |
| CALD1 | caldesmon 1 | -0.0186313 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0184845 |
| NABP1 | nucleic acid binding protein 1 | -0.0183909 |
| PDLIM5 | PDZ and LIM domain 5 | -0.018343 |
| OSMR | oncostatin M receptor | -0.0182482 |
| NOTCH3 | notch 3 | -0.0178107 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0177915 |
| SIK2 | salt-inducible kinase 2 | -0.0170808 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.0170398 |
| PRSS23 | protease, serine, 23 | -0.0167273 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0166894 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0165443 |
| CPA6 | carboxypeptidase A6 | -0.0164295 |
| FTL | ferritin, light polypeptide | -0.0162139 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0160388 |
| DGKH | diacylglycerol kinase, eta | -0.0160215 |
| PDE8A | phosphodiesterase 8A | -0.0156562 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0156228 |
| MYO10 | myosin X | -0.0155056 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0153892 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0153751 |
| PCBP3 | poly(rC) binding protein 3 | -0.0153278 |
| BPTF | bromodomain PHD finger transcription factor | -0.0152517 |
| RPL19 | ribosomal protein L19 | -0.0150314 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0150267 |
| SERF2 | small EDRK-rich factor 2 | -0.0146529 |
| RPLP1 | ribosomal protein, large, P1 | -0.0144877 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.014466 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0144248 |
| PALLD | palladin, cytoskeletal associated protein | -0.0142465 |
| RNF152 | ring finger protein 152 | -0.0139542 |
| MTAP | methylthioadenosine phosphorylase | -0.0139263 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0137997 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0137869 |
| MCL1 | myeloid cell leukemia 1 | -0.0137807 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0137308 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0136219 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0135141 |
| RAB31 | RAB31, member RAS oncogene family | -0.0135026 |
| SSBP3 | single stranded DNA binding protein 3 | -0.0134674 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0134615 |
| MYADM | myeloid-associated differentiation marker | -0.0131282 |
| EHBP1 | EH domain binding protein 1 | -0.0130744 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0129523 |
| ACLY | ATP citrate lyase | -0.0129127 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.01268 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0126182 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0125784 |
| RPLP2 | ribosomal protein, large, P2 | -0.0124362 |
