| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.116707 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0567927 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0458841 |
| NDRG1 | N-myc downstream regulated 1 | 0.044426 |
| FLNB | filamin B, beta | 0.0349853 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0341667 |
| LOXL2 | lysyl oxidase-like 2 | 0.0311499 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0308427 |
| SBF2 | SET binding factor 2 | 0.0308381 |
| OGA | O-GlcNAcase | 0.0300441 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.029826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0291551 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0289175 |
| SQSTM1 | sequestosome 1 | 0.0286549 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0280524 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0277415 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0271964 |
| STC1 | stanniocalcin 1 | 0.0265634 |
| GOLGA4 | golgin A4 | 0.0253518 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0250858 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0246168 |
| NAV2 | neuron navigator 2 | 0.0239708 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0238128 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.023159 |
| ZNF292 | zinc finger protein 292 | 0.0222201 |
| UBC | ubiquitin C | 0.022105 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218162 |
| ATP13A3 | ATPase type 13A3 | 0.0217573 |
| MEF2A | myocyte enhancer factor 2A | 0.0216184 |
| SETD5 | SET domain containing 5 | 0.0213159 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0205211 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0201536 |
| C1D | C1D nuclear receptor corepressor | 0.0200289 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0199982 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.019665 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195017 |
| SFTPA2 | surfactant protein A2 | 0.0194807 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0192742 |
| DSCAM | Down syndrome cell adhesion molecule | 0.018878 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0188449 |
| OPTN | optineurin | 0.0185867 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0183945 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0182687 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0181315 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0180865 |
| SEPTIN9 | septin 9 | 0.0180754 |
| GPC6 | glypican 6 | 0.0179817 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0176454 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0173876 |
| FNIP1 | folliculin interacting protein 1 | 0.017267 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.017211 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.01704 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.017039 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0169397 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0168578 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0167311 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0165388 |
| HELZ | helicase with zinc finger | 0.0161869 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0161675 |
| RNF24 | ring finger protein 24 | 0.0158441 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0158168 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0157603 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0157523 |
| NGLY1 | N-glycanase 1 | 0.0156341 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0155288 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0154933 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0152453 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0152291 |
| CD109 | CD109 molecule | 0.0151864 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.015122 |
| FBN1 | fibrillin 1 | 0.0150719 |
| WTAP | Wilms tumor 1 associated protein | 0.015045 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.01482 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0147029 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0145172 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0144914 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0144463 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.014434 |
| PRKD3 | protein kinase D3 | 0.0144212 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0144081 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0143957 |
| DTNA | dystrobrevin, alpha | 0.0141783 |
| MMP12 | matrix metallopeptidase 12 | 0.0141715 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0141674 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0141496 |
| EPAS1 | endothelial PAS domain protein 1 | 0.013936 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0136704 |
| HIP1 | huntingtin interacting protein 1 | 0.0135959 |
| COG5 | component of oligomeric golgi complex 5 | 0.0135794 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0134273 |
| ATXN1 | ataxin 1 | 0.013388 |
| ADM | adrenomedullin | 0.0133702 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.013301 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0132957 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0130167 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0129853 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0127739 |
| MYO9A | myosin IXA | 0.0127417 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0127084 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0126625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.160535 |
| TMSB10 | thymosin beta 10 | -0.159258 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158646 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.120897 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.108036 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0912916 |
| PODXL | podocalyxin-like | -0.0834803 |
| FN1 | fibronectin 1 | -0.0736722 |
| MAP1B | microtubule-associated protein 1B | -0.0632323 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0624746 |
| S100A10 | S100 calcium binding protein A10 | -0.0558502 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0548105 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0545066 |
| PRSS23 | protease, serine, 23 | -0.0542431 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0529514 |
| COL5A1 | collagen, type V, alpha 1 | -0.0527167 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0525629 |
| S100A6 | S100 calcium binding protein A6 | -0.052326 |
| HLA-B | major histocompatibility complex, class I, B | -0.0516603 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0516023 |
| NAV1 | neuron navigator 1 | -0.0507275 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0505465 |
| SUCNR1 | succinate receptor 1 | -0.0501738 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0488707 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0482043 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0469922 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0462709 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0454095 |
| CALR | calreticulin | -0.0447694 |
| PLAT | plasminogen activator, tissue | -0.0432917 |
| CDH13 | cadherin 13 | -0.0419491 |
| B2M | beta-2-microglobulin | -0.0407882 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0376893 |
| PKM | pyruvate kinase, muscle | -0.0370595 |
| RIGI | RNA sensor RIG-I | -0.0368102 |
| POTEF | POTE ankyrin domain family, member F | -0.0363507 |
| TAGLN2 | transgelin 2 | -0.0362408 |
| MX2 | MX dynamin-like GTPase 2 | -0.0362203 |
| CANX | calnexin | -0.0354244 |
| TPM4 | tropomyosin 4 | -0.0352352 |
| LMNA | lamin A/C | -0.0347659 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.033175 |
| TMSB4X | thymosin beta 4, X-linked | -0.0316643 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.031456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0307993 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0302513 |
| S100A4 | S100 calcium binding protein A4 | -0.0301602 |
| LRRC17 | leucine rich repeat containing 17 | -0.0299498 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0298956 |
| LDHA | lactate dehydrogenase A | -0.02983 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0294386 |
| ASPH | aspartate beta-hydroxylase | -0.0275717 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.027394 |
| FSTL1 | follistatin-like 1 | -0.027386 |
| COL3A1 | collagen, type III, alpha 1 | -0.026963 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.02694 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0268773 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0264618 |
| HLA-C | major histocompatibility complex, class I, C | -0.02626 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0261571 |
| CAVIN1 | caveolae associated protein 1 | -0.0257579 |
| COL5A2 | collagen, type V, alpha 2 | -0.0257023 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0255587 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0245123 |
| S100A11 | S100 calcium binding protein A11 | -0.0243523 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0240225 |
| CSTB | cystatin B (stefin B) | -0.0233838 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0233688 |
| IL7R | interleukin 7 receptor | -0.0229069 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0222529 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0220321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0218993 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0218336 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0217454 |
| KRT81 | keratin 81, type II | -0.0216403 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0215122 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0213083 |
| PLXNA2 | plexin A2 | -0.020799 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0206218 |
| CUX1 | cut-like homeobox 1 | -0.0202283 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0198648 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0195986 |
| AHNAK | AHNAK nucleoprotein | -0.019531 |
| MT1X | metallothionein 1X | -0.0193798 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0192957 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0191561 |
| CYTH3 | cytohesin 3 | -0.018863 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0188286 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0187868 |
| SP100 | SP100 nuclear antigen | -0.0183581 |
| RNF213 | ring finger protein 213 | -0.0183554 |
| ANXA2 | annexin A2 | -0.0180056 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0180035 |
| DCLK2 | doublecortin-like kinase 2 | -0.0178496 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0176514 |
| RASAL2 | RAS protein activator like 2 | -0.0174327 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0170827 |
| ENO1 | enolase 1, (alpha) | -0.0169636 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0166574 |
| SEPTIN7 | septin 7 | -0.0166251 |
