| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.372748 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.207571 |
| FMN1 | formin 1 | 0.118639 |
| HELZ | helicase with zinc finger | 0.0895918 |
| FAM13A | family with sequence similarity 13, member A | 0.0850194 |
| PRKCA | protein kinase C, alpha | 0.0827273 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0761769 |
| COL1A1 | collagen, type I, alpha 1 | 0.0754159 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0599199 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.059768 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.055871 |
| FNBP1 | formin binding protein 1 | 0.054239 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0538375 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0527238 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0522123 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0469623 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0451226 |
| MEF2A | myocyte enhancer factor 2A | 0.0444206 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0436397 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0423687 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0418733 |
| CDC27 | cell division cycle 27 | 0.0400114 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0377123 |
| LSAMP | limbic system-associated membrane protein | 0.0367943 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0366903 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0362797 |
| SEPTIN9 | septin 9 | 0.0358067 |
| CCNY | cyclin Y | 0.03556 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0340401 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0338102 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0331545 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0330164 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.032968 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.032605 |
| PTMA | prothymosin, alpha | 0.0323831 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0315332 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0312144 |
| COL3A1 | collagen, type III, alpha 1 | 0.0309659 |
| RPL19 | ribosomal protein L19 | 0.0309116 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.030909 |
| PLCB4 | phospholipase C, beta 4 | 0.0307521 |
| XPO1 | exportin 1 | 0.0307456 |
| SET | SET nuclear proto-oncogene | 0.0306974 |
| ENAH | enabled homolog (Drosophila) | 0.0305881 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0304638 |
| MAP4 | microtubule-associated protein 4 | 0.0302509 |
| PCM1 | pericentriolar material 1 | 0.0297364 |
| MAP1B | microtubule-associated protein 1B | 0.0296769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0296478 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0293915 |
| VMP1 | vacuole membrane protein 1 | 0.0289972 |
| RPL7 | ribosomal protein L7 | 0.0289787 |
| CENPF | centromere protein F, 350/400kDa | 0.0285192 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0282836 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282439 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281418 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0281004 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0280453 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0278699 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0273711 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0270934 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0269023 |
| PLAT | plasminogen activator, tissue | 0.0265884 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0265298 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0264879 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0263706 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0262716 |
| BBX | bobby sox homolog (Drosophila) | 0.0262472 |
| MEIS2 | Meis homeobox 2 | 0.0260492 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0260003 |
| PTK2 | protein tyrosine kinase 2 | 0.0257559 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0256406 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0253622 |
| NUP58 | nucleoporin 58 | 0.0252056 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0250665 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.024937 |
| FRMD4A | FERM domain containing 4A | 0.0247394 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0247183 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0246943 |
| GOLGA4 | golgin A4 | 0.024659 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0246181 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0244867 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0243757 |
| DTNA | dystrobrevin, alpha | 0.0242512 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0240475 |
| RPS2 | ribosomal protein S2 | 0.0239992 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0239894 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0239521 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0239185 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0238809 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0237279 |
| GPC5 | glypican 5 | 0.0235399 |
| LPIN1 | lipin 1 | 0.0235228 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0235044 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0234868 |
| RNF145 | ring finger protein 145 | 0.0231896 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0231782 |
| TRIB2 | tribbles pseudokinase 2 | 0.0230102 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0224264 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0224218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.0555133 |
| NRG1 | neuregulin 1 | -0.0499189 |
| RPL11 | ribosomal protein L11 | -0.0477232 |
| EFNA5 | ephrin-A5 | -0.0413183 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374071 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0361891 |
| PDE10A | phosphodiesterase 10A | -0.0352988 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0345497 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0337639 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0323688 |
| RPS24 | ribosomal protein S24 | -0.0323655 |
| IGF2 | insulin-like growth factor 2 | -0.031196 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0303449 |
| RPS8 | ribosomal protein S8 | -0.0295745 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0292183 |
| IER3 | immediate early response 3 | -0.0274518 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0270304 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0258604 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0255383 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0251163 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0247188 |
| RIGI | RNA sensor RIG-I | -0.024669 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0244585 |
| HLA-B | major histocompatibility complex, class I, B | -0.0240084 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0239773 |
| KLHL13 | kelch-like family member 13 | -0.0238622 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0238213 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0235987 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0228565 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0226568 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0226299 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0218835 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0218418 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0217256 |
| TMEM263 | transmembrane protein 263 | -0.0215439 |
| TMF1 | TATA element modulatory factor 1 | -0.0212311 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0207546 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0206173 |
| TMSB10 | thymosin beta 10 | -0.0203564 |
| S100A6 | S100 calcium binding protein A6 | -0.0202945 |
| RPL13A | ribosomal protein L13a | -0.020065 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0200228 |
| CAVIN1 | caveolae associated protein 1 | -0.0200225 |
| KIAA1217 | KIAA1217 | -0.0197874 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0197829 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0196715 |
| DIAPH2 | diaphanous-related formin 2 | -0.0195929 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0194368 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0194282 |
| ETV6 | ets variant 6 | -0.0192575 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0192302 |
| RPS16 | ribosomal protein S16 | -0.0190951 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0188637 |
| RPL35A | ribosomal protein L35a | -0.0184013 |
| LAMB3 | laminin, beta 3 | -0.0182353 |
| RPS25 | ribosomal protein S25 | -0.0182333 |
| MYO1D | myosin ID | -0.0179342 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0178847 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0178427 |
| S100A10 | S100 calcium binding protein A10 | -0.0177427 |
| MCU | mitochondrial calcium uniporter | -0.0177064 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0176052 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0174937 |
| MT2A | metallothionein 2A | -0.0172519 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0172236 |
| GPC6 | glypican 6 | -0.0171098 |
| VCL | vinculin | -0.0170194 |
| AMOTL1 | angiomotin like 1 | -0.0169894 |
| ODR4 | odr-4 GPCR localization factor homolog | -0.0168957 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0168921 |
| PARD3 | par-3 family cell polarity regulator | -0.0168898 |
| FHL2 | four and a half LIM domains 2 | -0.016815 |
| ACTN4 | actinin, alpha 4 | -0.0168084 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0168011 |
| TBCA | tubulin folding cofactor A | -0.0167878 |
| LAMC2 | laminin, gamma 2 | -0.0167284 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0165823 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0164975 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0163322 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | -0.0163306 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0161901 |
| RPL34 | ribosomal protein L34 | -0.0161724 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0161043 |
| UBL5 | ubiquitin-like 5 | -0.0160362 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0159853 |
| NREP | neuronal regeneration related protein | -0.0159051 |
| ENO1 | enolase 1, (alpha) | -0.015873 |
| CTBP2 | C-terminal binding protein 2 | -0.0158724 |
| HMGB1 | high mobility group box 1 | -0.0158525 |
| COL5A1 | collagen, type V, alpha 1 | -0.0158131 |
| COL4A6 | collagen, type IV, alpha 6 | -0.015789 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0157718 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0157596 |
| COX19 | COX19 cytochrome c oxidase assembly factor | -0.0156342 |
| LAMB1 | laminin, beta 1 | -0.0156065 |
| LDHA | lactate dehydrogenase A | -0.0156056 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0155724 |
| SRPK2 | SRSF protein kinase 2 | -0.0154898 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -0.0154107 |
| RPS29 | ribosomal protein S29 | -0.0153426 |
