| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0684799 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0454387 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0441889 |
| FNIP1 | folliculin interacting protein 1 | 0.043625 |
| GOLGB1 | golgin B1 | 0.0419234 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0402411 |
| XAF1 | XIAP associated factor 1 | 0.0401713 |
| TXNIP | thioredoxin interacting protein | 0.0370248 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0345752 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332991 |
| NPSR1 | neuropeptide S receptor 1 | 0.0326092 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0316457 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0315108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0309435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0306176 |
| EFHD2 | EF-hand domain family, member D2 | 0.0303547 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0293009 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0278579 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0274244 |
| MCU | mitochondrial calcium uniporter | 0.0268206 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0267483 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0265486 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0263412 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0257342 |
| CCDC146 | coiled-coil domain containing 146 | 0.0256495 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0252954 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0252159 |
| APOL6 | apolipoprotein L, 6 | 0.0245959 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0243519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0242275 |
| NDRG1 | N-myc downstream regulated 1 | 0.0240744 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.023925 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0238546 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0231508 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0227146 |
| USP8 | ubiquitin specific peptidase 8 | 0.0227025 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0226829 |
| PHF3 | PHD finger protein 3 | 0.0224102 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0222476 |
| KIF16B | kinesin family member 16B | 0.0220243 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0217835 |
| APOL1 | apolipoprotein L, 1 | 0.0214257 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0212726 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0212132 |
| PLSCR2 | phospholipid scramblase 2 | 0.0211129 |
| RNF149 | ring finger protein 149 | 0.0210363 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0204927 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0202773 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0202636 |
| MICU2 | mitochondrial calcium uptake 2 | 0.0201649 |
| SEC24D | SEC24 family member D | 0.0200584 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0199893 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0199805 |
| SEC24A | SEC24 family member A | 0.019788 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0197732 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0190451 |
| RBM39 | RNA binding motif protein 39 | 0.0188475 |
| SFXN1 | sideroflexin 1 | 0.0188199 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0187957 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0185253 |
| ABHD2 | abhydrolase domain containing 2 | 0.01847 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0180846 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0175317 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0174062 |
| TFRC | transferrin receptor | 0.017325 |
| AGR2 | anterior gradient 2 | 0.0173235 |
| STXBP1 | syntaxin binding protein 1 | 0.0172926 |
| PRKD3 | protein kinase D3 | 0.0172169 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0171806 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0170964 |
| CTSS | cathepsin S | 0.0169619 |
| PTGR1 | prostaglandin reductase 1 | 0.0169508 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0165869 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0165375 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0164999 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0164728 |
| RAD51B | RAD51 paralog B | 0.0161992 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0161853 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0159146 |
| IRF1 | interferon regulatory factor 1 | 0.015672 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0155715 |
| NIPSNAP2 | nipsnap homolog 2 | 0.015184 |
| TMEM263 | transmembrane protein 263 | 0.0150969 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0150549 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0148159 |
| CCNL1 | cyclin L1 | 0.0147287 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0146349 |
| TOR1AIP1 | torsin A interacting protein 1 | 0.0145483 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0145207 |
| IL6ST | interleukin 6 signal transducer | 0.0145029 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0143978 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0143685 |
| TRIM2 | tripartite motif containing 2 | 0.0143016 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0142878 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0142567 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0141866 |
| USP53 | ubiquitin specific peptidase 53 | 0.0141846 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0141825 |
| ZFP64 | ZFP64 zinc finger protein | 0.0141747 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0140341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.180837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.147085 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141519 |
| PKM | pyruvate kinase, muscle | -0.13681 |
| LOC112694756 | uncharaterized LOC112694756 | -0.117182 |
| LCN2 | lipocalin 2 | -0.104188 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0998582 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0920816 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0808439 |
| PTMA | prothymosin, alpha | -0.0768237 |
| RUNX1 | runt-related transcription factor 1 | -0.0762228 |
| TMSB10 | thymosin beta 10 | -0.0755449 |
| ENO1 | enolase 1, (alpha) | -0.0741388 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0741105 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0731002 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0637919 |
| RNF43 | ring finger protein 43 | -0.0629039 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0618924 |
| CALR | calreticulin | -0.0613085 |
| JUN | jun proto-oncogene | -0.0608122 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0607556 |
| RPL23 | ribosomal protein L23 | -0.0566837 |
| PERP | PERP, TP53 apoptosis effector | -0.0554158 |
| PCBP2 | poly(rC) binding protein 2 | -0.0525878 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0512519 |
| LDHA | lactate dehydrogenase A | -0.0506889 |
| MYO1E | myosin IE | -0.0493052 |
| AHNAK | AHNAK nucleoprotein | -0.049033 |
| HLA-C | major histocompatibility complex, class I, C | -0.0484026 |
| MLPH | melanophilin | -0.0481064 |
| STK24 | serine/threonine kinase 24 | -0.0475203 |
| EPCAM | epithelial cell adhesion molecule | -0.0466636 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0463914 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0461884 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0457925 |
| ACTN4 | actinin, alpha 4 | -0.0454123 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.044299 |
| RPS27A | ribosomal protein S27a | -0.0432454 |
| ANXA2 | annexin A2 | -0.0429749 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0417372 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0417285 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0413536 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.038296 |
| HLA-B | major histocompatibility complex, class I, B | -0.0373455 |
| APP | amyloid beta (A4) precursor protein | -0.0369432 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0369269 |
| OGA | O-GlcNAcase | -0.0366409 |
| CANX | calnexin | -0.0359163 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0352642 |
| RRBP1 | ribosome binding protein 1 | -0.0351482 |
| TMEM62 | transmembrane protein 62 | -0.0348058 |
| KRT8 | keratin 8, type II | -0.0342635 |
| SPAG9 | sperm associated antigen 9 | -0.0341059 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0340658 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0340635 |
| EPHB2 | EPH receptor B2 | -0.0336279 |
| FAT1 | FAT atypical cadherin 1 | -0.0331203 |
| ACTG1 | actin gamma 1 | -0.0328467 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0327554 |
| HLA-E | major histocompatibility complex, class I, E | -0.0322874 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0318724 |
| NCKAP5 | NCK-associated protein 5 | -0.0317277 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0316714 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0314101 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0313452 |
| HDLBP | high density lipoprotein binding protein | -0.0306246 |
| POTEF | POTE ankyrin domain family, member F | -0.0304926 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0303684 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0302158 |
| BRD2 | bromodomain containing 2 | -0.0300118 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0293429 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0289133 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0288344 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0288096 |
| H1-0 | H1.0 linker histone | -0.0287378 |
| HDAC4 | histone deacetylase 4 | -0.0286879 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0284726 |
| MEIS2 | Meis homeobox 2 | -0.0283937 |
| DSPP | dentin sialophosphoprotein | -0.0282772 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.028107 |
| TMC5 | transmembrane channel-like 5 | -0.0280167 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0278714 |
| FTL | ferritin, light polypeptide | -0.027768 |
| GSDMB | gasdermin B | -0.027639 |
| HLA-A | major histocompatibility complex, class I, A | -0.0275187 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0273905 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0272953 |
| RPS29 | ribosomal protein S29 | -0.0270086 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0269356 |
| MSI2 | musashi RNA-binding protein 2 | -0.0268662 |
| TRERF1 | transcriptional regulating factor 1 | -0.0268118 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267471 |
| SMAD3 | SMAD family member 3 | -0.0266949 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0264629 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0264239 |
| RPS3 | ribosomal protein S3 | -0.0263885 |
| ATP11A | ATPase, class VI, type 11A | -0.0263821 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.026339 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.026277 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0262038 |
