| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.241334 |
| CADM1 | cell adhesion molecule 1 | 0.159239 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.135266 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.107746 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0957687 |
| MT2A | metallothionein 2A | 0.0780193 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0771035 |
| CDH13 | cadherin 13 | 0.0713782 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0713359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0668754 |
| ATP13A3 | ATPase type 13A3 | 0.0648871 |
| VEGFA | vascular endothelial growth factor A | 0.0630769 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0624771 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.061067 |
| GOLGA4 | golgin A4 | 0.0608194 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0607393 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0597894 |
| PDE10A | phosphodiesterase 10A | 0.0585534 |
| RPS8 | ribosomal protein S8 | 0.0583004 |
| ZNF292 | zinc finger protein 292 | 0.0525303 |
| COL1A1 | collagen, type I, alpha 1 | 0.0489976 |
| RPS6 | ribosomal protein S6 | 0.0469872 |
| TFG | TRK-fused gene | 0.0457592 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0446025 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0433397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0423035 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0419903 |
| PTK2 | protein tyrosine kinase 2 | 0.0416889 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0404186 |
| QKI | QKI, KH domain containing, RNA binding | 0.0390351 |
| MRTFA | myocardin related transcription factor A | 0.0389502 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0389366 |
| PTMA | prothymosin, alpha | 0.038221 |
| RUNX1 | runt-related transcription factor 1 | 0.0375355 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0358824 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0358681 |
| EGFR | epidermal growth factor receptor | 0.0354949 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353367 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0351275 |
| FMNL2 | formin-like 2 | 0.0348176 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0347189 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0336817 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0332331 |
| SETD5 | SET domain containing 5 | 0.0330386 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0322467 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0319052 |
| RBM39 | RNA binding motif protein 39 | 0.0318635 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0316164 |
| RPS12 | ribosomal protein S12 | 0.0315679 |
| TSC22D2 | TSC22 domain family, member 2 | 0.031206 |
| PDE8A | phosphodiesterase 8A | 0.031061 |
| RPL35A | ribosomal protein L35a | 0.0309173 |
| RPL8 | ribosomal protein L8 | 0.0308791 |
| RPL11 | ribosomal protein L11 | 0.0308654 |
| MAP4 | microtubule-associated protein 4 | 0.0303999 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0296863 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0296842 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0296691 |
| MTDH | metadherin | 0.0295122 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0294313 |
| USP3 | ubiquitin specific peptidase 3 | 0.0293036 |
| RLF | rearranged L-myc fusion | 0.0292799 |
| B2M | beta-2-microglobulin | 0.0292406 |
| NAV2 | neuron navigator 2 | 0.0292046 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.028788 |
| RPS3 | ribosomal protein S3 | 0.0287279 |
| S100A9 | S100 calcium binding protein A9 | 0.0280879 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0276336 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0275412 |
| TRAM1 | translocation associated membrane protein 1 | 0.0273568 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0271447 |
| RPS2 | ribosomal protein S2 | 0.0270732 |
| IER3 | immediate early response 3 | 0.0269821 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0265055 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0263885 |
| RPL7 | ribosomal protein L7 | 0.0263763 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0261561 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0258011 |
| BBX | bobby sox homolog (Drosophila) | 0.0256337 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0255823 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0255027 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0252879 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0252046 |
| HIP1 | huntingtin interacting protein 1 | 0.0251214 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0250343 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0250069 |
| RYBP | RING1 and YY1 binding protein | 0.0249903 |
| CCNY | cyclin Y | 0.0249284 |
| MATR3 | matrin 3 | 0.0248894 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0248628 |
| ADM | adrenomedullin | 0.0248336 |
| PRELID2 | PRELI domain containing 2 | 0.0246443 |
| TMEM165 | transmembrane protein 165 | 0.0245229 |
| SPAG9 | sperm associated antigen 9 | 0.024509 |
| RPL28 | ribosomal protein L28 | 0.02414 |
| COL5A1 | collagen, type V, alpha 1 | 0.0238803 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0238315 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0237356 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0237086 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0234417 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.338923 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.134252 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0934556 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0692142 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0647501 |
| LDHA | lactate dehydrogenase A | -0.0583585 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0581864 |
| GLIS3 | GLIS family zinc finger 3 | -0.0558094 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0548791 |
| HMGA2 | high mobility group AT-hook 2 | -0.0446392 |
| ASPH | aspartate beta-hydroxylase | -0.0425397 |
| OSMR | oncostatin M receptor | -0.042191 |
| CD44 | CD44 molecule (Indian blood group) | -0.0410722 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0391196 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0366901 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0363977 |
| FBN1 | fibrillin 1 | -0.0361174 |
| PALLD | palladin, cytoskeletal associated protein | -0.0356217 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0334538 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0329868 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0309156 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0304128 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0303866 |
| VCL | vinculin | -0.0303064 |
| INHBA | inhibin, beta A | -0.0298777 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0272563 |
| RIGI | RNA sensor RIG-I | -0.026604 |
| COL1A2 | collagen, type I, alpha 2 | -0.026442 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0260261 |
| TMSB10 | thymosin beta 10 | -0.0253567 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0249808 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0243835 |
| CALD1 | caldesmon 1 | -0.0243087 |
| NREP | neuronal regeneration related protein | -0.0237664 |
| EGR1 | early growth response 1 | -0.0235862 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0229614 |
| VIM | vimentin | -0.0228832 |
| HLA-B | major histocompatibility complex, class I, B | -0.022692 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0226481 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0224933 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0223501 |
| APP | amyloid beta (A4) precursor protein | -0.0219525 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0212027 |
| CAVIN1 | caveolae associated protein 1 | -0.0209888 |
| JAK2 | Janus kinase 2 | -0.020385 |
| ANXA2 | annexin A2 | -0.0196369 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0193536 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0193004 |
| EBF1 | early B-cell factor 1 | -0.0192118 |
| PLEC | plectin | -0.0189528 |
| CTSB | cathepsin B | -0.0188336 |
| FSTL1 | follistatin-like 1 | -0.0186591 |
| SVIL | supervillin | -0.0186464 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0180898 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.017876 |
| TPM4 | tropomyosin 4 | -0.0176853 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0176569 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0174918 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0174181 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0168279 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0166064 |
| ACTG1 | actin gamma 1 | -0.016587 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0164027 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0163275 |
| NRP1 | neuropilin 1 | -0.0162614 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0161759 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0148793 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0147036 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0146826 |
| KLF6 | Kruppel-like factor 6 | -0.0146701 |
| CNTN5 | contactin 5 | -0.0146364 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0145012 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0144292 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0143631 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0143425 |
| PRSS23 | protease, serine, 23 | -0.0140839 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.014057 |
| STK38L | serine/threonine kinase 38 like | -0.0139264 |
| FHL2 | four and a half LIM domains 2 | -0.0138989 |
| SDC2 | syndecan 2 | -0.0138896 |
| AHNAK | AHNAK nucleoprotein | -0.0136914 |
| PKM | pyruvate kinase, muscle | -0.0136049 |
| AOPEP | aminopeptidase O (putative) | -0.0133877 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0132319 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0132221 |
| DUSP6 | dual specificity phosphatase 6 | -0.0131487 |
| CCND1 | cyclin D1 | -0.0130997 |
| SMAD3 | SMAD family member 3 | -0.0127029 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0126323 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0124605 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0123901 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0123475 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0121728 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0121146 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0120896 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0120538 |
| HLA-C | major histocompatibility complex, class I, C | -0.012033 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.011962 |
| FRMD4A | FERM domain containing 4A | -0.0118444 |
| TPM1 | tropomyosin 1 (alpha) | -0.0118179 |
