| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.161071 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.155925 |
| RPS6 | ribosomal protein S6 | 0.0913679 |
| NDRG1 | N-myc downstream regulated 1 | 0.0857489 |
| GOLGA4 | golgin A4 | 0.0803505 |
| FAM13A | family with sequence similarity 13, member A | 0.0615351 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0585959 |
| RPL35A | ribosomal protein L35a | 0.0566611 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0555656 |
| RPS2 | ribosomal protein S2 | 0.0545185 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0528247 |
| RPL11 | ribosomal protein L11 | 0.0498653 |
| EREG | epiregulin | 0.0475315 |
| AREG | amphiregulin | 0.0461364 |
| TXNIP | thioredoxin interacting protein | 0.045788 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0452239 |
| RPL34 | ribosomal protein L34 | 0.0448201 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0438086 |
| GDF15 | growth differentiation factor 15 | 0.0428725 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0399088 |
| RPL12 | ribosomal protein L12 | 0.0388543 |
| RPL7 | ribosomal protein L7 | 0.038071 |
| RPL32 | ribosomal protein L32 | 0.0380399 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0365152 |
| RPS8 | ribosomal protein S8 | 0.0362783 |
| RBM39 | RNA binding motif protein 39 | 0.0362735 |
| S100P | S100 calcium binding protein P | 0.0331369 |
| RPS19 | ribosomal protein S19 | 0.033062 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0311108 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0309613 |
| SETD5 | SET domain containing 5 | 0.0304885 |
| ATF4 | activating transcription factor 4 | 0.0301748 |
| RPS12 | ribosomal protein S12 | 0.0301427 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0299599 |
| RPL28 | ribosomal protein L28 | 0.0295789 |
| RPL37A | ribosomal protein L37a | 0.0295509 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0294108 |
| RPL36 | ribosomal protein L36 | 0.0288537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0287894 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0271297 |
| RPLP0 | ribosomal protein, large, P0 | 0.027037 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0266863 |
| ZNF292 | zinc finger protein 292 | 0.0264351 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0262191 |
| RPS29 | ribosomal protein S29 | 0.0259446 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0259233 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0255692 |
| FTL | ferritin, light polypeptide | 0.0255556 |
| RNF145 | ring finger protein 145 | 0.0253331 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246872 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0246769 |
| RPS13 | ribosomal protein S13 | 0.0243067 |
| RPS23 | ribosomal protein S23 | 0.0240556 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0238658 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0237878 |
| MED13L | mediator complex subunit 13-like | 0.0237776 |
| RPS14 | ribosomal protein S14 | 0.0236294 |
| RPL21 | ribosomal protein L21 | 0.0231332 |
| RPS27 | ribosomal protein S27 | 0.0231186 |
| RPS3 | ribosomal protein S3 | 0.0227672 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0223403 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0221885 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0221018 |
| WASF2 | WAS protein family, member 2 | 0.0220273 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0216651 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0216523 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0214281 |
| SELENOF | selenoprotein F | 0.0206526 |
| SFXN1 | sideroflexin 1 | 0.0206184 |
| RPL8 | ribosomal protein L8 | 0.0205256 |
| S100A9 | S100 calcium binding protein A9 | 0.0204709 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0202922 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0200256 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0197292 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0194522 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.019443 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0194013 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0193963 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0193081 |
| NCOR1 | nuclear receptor corepressor 1 | 0.019168 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0190996 |
| NUP58 | nucleoporin 58 | 0.0189626 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0187403 |
| TXNRD1 | thioredoxin reductase 1 | 0.0186689 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0186375 |
| SRP54 | signal recognition particle 54kDa | 0.0185401 |
| AGR2 | anterior gradient 2 | 0.0184163 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0183533 |
| PNN | pinin, desmosome associated protein | 0.0182012 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0181622 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.017893 |
| YME1L1 | YME1-like 1 ATPase | 0.0177758 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0176878 |
| NKTR | natural killer cell triggering receptor | 0.0176701 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0176165 |
| TFG | TRK-fused gene | 0.0175439 |
| SEC24D | SEC24 family member D | 0.0175387 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0173443 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0173417 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0171759 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.189304 |
| KRT18 | keratin 18, type I | -0.13312 |
| TMSB10 | thymosin beta 10 | -0.123169 |
| LOC112694756 | uncharaterized LOC112694756 | -0.120123 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.112707 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.110595 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.092527 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.092037 |
| KRT8 | keratin 8, type II | -0.0841613 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0800167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0799303 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.079808 |
| FAT1 | FAT atypical cadherin 1 | -0.0769829 |
| PKM | pyruvate kinase, muscle | -0.0761159 |
| LDHA | lactate dehydrogenase A | -0.0724656 |
| AHNAK | AHNAK nucleoprotein | -0.0709362 |
| PIGR | polymeric immunoglobulin receptor | -0.0708568 |
| ENO1 | enolase 1, (alpha) | -0.0705009 |
| NPSR1 | neuropeptide S receptor 1 | -0.069718 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0676256 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0627167 |
| UBC | ubiquitin C | -0.0618159 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0563013 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0500591 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0498849 |
| APP | amyloid beta (A4) precursor protein | -0.0496793 |
| RPS27A | ribosomal protein S27a | -0.0488679 |
| MYO1E | myosin IE | -0.0486054 |
| ITGA6 | integrin, alpha 6 | -0.0481059 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0472697 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0446056 |
| RPL4 | ribosomal protein L4 | -0.0417419 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0413957 |
| DSPP | dentin sialophosphoprotein | -0.0408748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0394858 |
| CALR | calreticulin | -0.0393864 |
| KRT19 | keratin 19, type I | -0.0392941 |
| ASPH | aspartate beta-hydroxylase | -0.0392216 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0357428 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0351066 |
| TPM4 | tropomyosin 4 | -0.0346948 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0342599 |
| PCBP2 | poly(rC) binding protein 2 | -0.0341228 |
| POTEF | POTE ankyrin domain family, member F | -0.033828 |
| ACTN4 | actinin, alpha 4 | -0.0330157 |
| FHIT | fragile histidine triad | -0.0324821 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0316433 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0315851 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314067 |
| CANX | calnexin | -0.0313907 |
| EPCAM | epithelial cell adhesion molecule | -0.0309779 |
| S100A6 | S100 calcium binding protein A6 | -0.0300921 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0296765 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.028757 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0285626 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0282981 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0280595 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0273178 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0271243 |
| GPHN | gephyrin | -0.026931 |
| ANXA2 | annexin A2 | -0.0269307 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0268989 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0267273 |
| PGK1 | phosphoglycerate kinase 1 | -0.0265583 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.026345 |
| RPL3 | ribosomal protein L3 | -0.0261639 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0257267 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0254483 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0252326 |
| TMSB4X | thymosin beta 4, X-linked | -0.0249821 |
| EPHB2 | EPH receptor B2 | -0.0248972 |
| EZR | ezrin | -0.0246913 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0240498 |
| SMYD3 | SET and MYND domain containing 3 | -0.023958 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0237971 |
| HMGB2 | high mobility group box 2 | -0.0234499 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0233755 |
| LMO7 | LIM domain 7 | -0.0233597 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0232673 |
| DIAPH2 | diaphanous-related formin 2 | -0.0231958 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0230988 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230393 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0229344 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.022776 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0226008 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0225115 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0223056 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0217863 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0216601 |
| CCND1 | cyclin D1 | -0.0211275 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0210107 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0208642 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0207218 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0206348 |
| PLEC | plectin | -0.0205773 |
| ANXA11 | annexin A11 | -0.0205408 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0205087 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0203628 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0202614 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0202481 |
