| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0745067 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0720997 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0686927 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0636583 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0586742 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0556416 |
| EFNA5 | ephrin-A5 | 0.0530093 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0512011 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0484752 |
| LOX | lysyl oxidase | 0.0480448 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0452983 |
| HMGA2 | high mobility group AT-hook 2 | 0.0442325 |
| CDH13 | cadherin 13 | 0.0406702 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0391701 |
| FN1 | fibronectin 1 | 0.0390466 |
| NAV2 | neuron navigator 2 | 0.0372473 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0371626 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0371422 |
| FAM20C | family with sequence similarity 20, member C | 0.0355415 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0352937 |
| EGFR | epidermal growth factor receptor | 0.0349281 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0325345 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.031963 |
| USP34 | ubiquitin specific peptidase 34 | 0.031663 |
| MEF2A | myocyte enhancer factor 2A | 0.0309592 |
| TGM2 | transglutaminase 2 | 0.0302524 |
| MTSS1 | metastasis suppressor 1 | 0.0290141 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0285045 |
| VEGFA | vascular endothelial growth factor A | 0.0283887 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0283795 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0275632 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271144 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0270747 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0262988 |
| NPAS2 | neuronal PAS domain protein 2 | 0.02516 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0250262 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0246055 |
| VIM | vimentin | 0.0243728 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0240832 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0235736 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0232858 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.022989 |
| RAI14 | retinoic acid induced 14 | 0.0227363 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0222118 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0219157 |
| DST | dystonin | 0.0216333 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0215903 |
| OSMR | oncostatin M receptor | 0.0215326 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0214272 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0212708 |
| NDRG1 | N-myc downstream regulated 1 | 0.0212657 |
| STC1 | stanniocalcin 1 | 0.0211414 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0209066 |
| ETV6 | ets variant 6 | 0.0207598 |
| RAD51B | RAD51 paralog B | 0.020746 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0205851 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201593 |
| SEPTIN9 | septin 9 | 0.0201341 |
| PYGL | phosphorylase, glycogen, liver | 0.0198975 |
| NRG1 | neuregulin 1 | 0.0198055 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0197494 |
| OXR1 | oxidation resistance 1 | 0.019643 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0194754 |
| NRP1 | neuropilin 1 | 0.0193878 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0191893 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0185446 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0183851 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0183813 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0181087 |
| ATXN1 | ataxin 1 | 0.0180667 |
| LOXL2 | lysyl oxidase-like 2 | 0.0179481 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0175773 |
| TMEM165 | transmembrane protein 165 | 0.0169154 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0166973 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0166567 |
| NGLY1 | N-glycanase 1 | 0.0166558 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.016084 |
| DSCAM | Down syndrome cell adhesion molecule | 0.015596 |
| OPTN | optineurin | 0.0155103 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0153325 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0153181 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0152756 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0151954 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0149344 |
| FBN1 | fibrillin 1 | 0.0149267 |
| EHBP1 | EH domain binding protein 1 | 0.0149214 |
| GLIS3 | GLIS family zinc finger 3 | 0.0149106 |
| GPC6 | glypican 6 | 0.0148755 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0148604 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0148156 |
| CUX1 | cut-like homeobox 1 | 0.0147194 |
| FAM107B | family with sequence similarity 107, member B | 0.0145322 |
| FNIP1 | folliculin interacting protein 1 | 0.0143846 |
| NHSL1 | NHS-like 1 | 0.0143402 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0143389 |
| GLCCI1 | glucocorticoid induced 1 | 0.0142445 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0140382 |
| MCL1 | myeloid cell leukemia 1 | 0.0140188 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0139109 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0138958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122381 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0824479 |
| FTL | ferritin, light polypeptide | -0.054731 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0467348 |
| PTMA | prothymosin, alpha | -0.0399715 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0377529 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0307212 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.030615 |
| IER3 | immediate early response 3 | -0.0250969 |
| USP3 | ubiquitin specific peptidase 3 | -0.024949 |
| RPS24 | ribosomal protein S24 | -0.0246452 |
| RPLP1 | ribosomal protein, large, P1 | -0.0245645 |
| CANX | calnexin | -0.023373 |
| RPLP0 | ribosomal protein, large, P0 | -0.023364 |
| OGA | O-GlcNAcase | -0.0227016 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0221802 |
| TMSB10 | thymosin beta 10 | -0.0212656 |
| WDR45B | WD repeat domain 45B | -0.0198207 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0192457 |
| RPL35A | ribosomal protein L35a | -0.0189448 |
| RPL23 | ribosomal protein L23 | -0.018459 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0184188 |
| LMAN1 | lectin, mannose-binding, 1 | -0.018382 |
| RBM39 | RNA binding motif protein 39 | -0.01798 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.017946 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0177591 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0163396 |
| YBX1 | Y box binding protein 1 | -0.0158031 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0153295 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0147916 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0147866 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0146859 |
| RPS21 | ribosomal protein S21 | -0.0145608 |
| TXNRD1 | thioredoxin reductase 1 | -0.014438 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0143389 |
| RLF | rearranged L-myc fusion | -0.0142474 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0140718 |
| CALR | calreticulin | -0.0135596 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0135024 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0135003 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0134798 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0131534 |
| ACTG1 | actin gamma 1 | -0.0129962 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0129908 |
| SEPTIN7 | septin 7 | -0.0129813 |
| AHNAK | AHNAK nucleoprotein | -0.0128982 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0128492 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0127281 |
| VDAC1 | voltage-dependent anion channel 1 | -0.012383 |
| RPS19 | ribosomal protein S19 | -0.0123567 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.012245 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0122165 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0121994 |
| RPS11 | ribosomal protein S11 | -0.012059 |
| TMEM123 | transmembrane protein 123 | -0.0119712 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0119561 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0119544 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0119179 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.011859 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0116256 |
| RPL12 | ribosomal protein L12 | -0.0115756 |
| QKI | QKI, KH domain containing, RNA binding | -0.0115258 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0115011 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0112316 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0111782 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0111211 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.011088 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0110536 |
| LDHA | lactate dehydrogenase A | -0.0110527 |
| SPAG9 | sperm associated antigen 9 | -0.0110376 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0109973 |
| MT2A | metallothionein 2A | -0.0108408 |
| KLF6 | Kruppel-like factor 6 | -0.0108172 |
| ANXA1 | annexin A1 | -0.0106808 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0106346 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0105098 |
| TKT | transketolase | -0.0105031 |
| RPS5 | ribosomal protein S5 | -0.0104428 |
| RPS25 | ribosomal protein S25 | -0.0104155 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0103785 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0103682 |
| EZR | ezrin | -0.0101419 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00989765 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.00982068 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0097768 |
| FAM162A | family with sequence similarity 162, member A | -0.00966878 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00966571 |
| APP | amyloid beta (A4) precursor protein | -0.00960504 |
| RIOK3 | RIO kinase 3 | -0.00957401 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00953634 |
| ENO1 | enolase 1, (alpha) | -0.00940499 |
| MORF4L2 | mortality factor 4 like 2 | -0.00936997 |
| LOC112694756 | uncharaterized LOC112694756 | -0.00918186 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00915134 |
| RHEB | Ras homolog enriched in brain | -0.00914654 |
| RPL38 | ribosomal protein L38 | -0.00899829 |
| YBX3 | Y box binding protein 3 | -0.00896525 |
| ARF1 | ADP-ribosylation factor 1 | -0.00894112 |
| RPN2 | ribophorin II | -0.00893791 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.00893419 |
