| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.201752 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.193983 |
| VIM | vimentin | 0.190852 |
| TMSB10 | thymosin beta 10 | 0.113879 |
| IGF2 | insulin-like growth factor 2 | 0.0656183 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0585425 |
| PFN1 | profilin 1 | 0.0577715 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0558139 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0550216 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0544068 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0535371 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0527437 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.048175 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0450812 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0418023 |
| RPL8 | ribosomal protein L8 | 0.0403732 |
| HDAC9 | histone deacetylase 9 | 0.0394862 |
| FLNB | filamin B, beta | 0.0375391 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0367529 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0345975 |
| COPA | coatomer protein complex, subunit alpha | 0.033233 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0316223 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0298221 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.029564 |
| POTEF | POTE ankyrin domain family, member F | 0.0294157 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0287166 |
| LDHA | lactate dehydrogenase A | 0.0273818 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0264481 |
| PYGL | phosphorylase, glycogen, liver | 0.0258392 |
| RBM25 | RNA binding motif protein 25 | 0.0252898 |
| EGR1 | early growth response 1 | 0.0252786 |
| FTL | ferritin, light polypeptide | 0.025145 |
| ERBIN | erbb2 interacting protein | 0.0248401 |
| CMIP | c-Maf inducing protein | 0.0247576 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0237567 |
| HMGA1 | high mobility group AT-hook 1 | 0.0231069 |
| RPL35A | ribosomal protein L35a | 0.0228844 |
| PRR16 | proline rich 16 | 0.0222907 |
| THBS1 | thrombospondin 1 | 0.0217877 |
| TAGLN2 | transgelin 2 | 0.0217639 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0216446 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0210952 |
| SFTPA2 | surfactant protein A2 | 0.0208169 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0207563 |
| MYADM | myeloid-associated differentiation marker | 0.0203921 |
| FMNL2 | formin-like 2 | 0.0203375 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0202882 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0200979 |
| HMGA2 | high mobility group AT-hook 2 | 0.0200759 |
| TPM4 | tropomyosin 4 | 0.0193985 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0193164 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0189529 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0188232 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0186256 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0185662 |
| AK1 | adenylate kinase 1 | 0.0184851 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0179722 |
| MCL1 | myeloid cell leukemia 1 | 0.0178836 |
| LMNA | lamin A/C | 0.0177923 |
| JUN | jun proto-oncogene | 0.0176947 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0172639 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0172572 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0170763 |
| HLA-A | major histocompatibility complex, class I, A | 0.0170169 |
| RPS29 | ribosomal protein S29 | 0.0169538 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.0168676 |
| FLNA | filamin A, alpha | 0.0167835 |
| HDGF | hepatoma-derived growth factor | 0.0167289 |
| CSNK1E | casein kinase 1, epsilon | 0.0166916 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0166569 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0164594 |
| KLF6 | Kruppel-like factor 6 | 0.0164293 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0163008 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0159601 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0153847 |
| RPS14 | ribosomal protein S14 | 0.0153028 |
| RHOA | ras homolog family member A | 0.0152224 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0151789 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0151506 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.015046 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0150313 |
| PCBP2 | poly(rC) binding protein 2 | 0.0149789 |
| TBC1D19 | TBC1 domain family, member 19 | 0.0149689 |
| JUP | junction plakoglobin | 0.0149657 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0147902 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0145806 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0145149 |
| CCN2 | cellular communication network factor 2 | 0.014455 |
| BCL2L1 | BCL2-like 1 | 0.0141867 |
| MITF | microphthalmia-associated transcription factor | 0.0141859 |
| HMGB1 | high mobility group box 1 | 0.0140843 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0140545 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0140533 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0140282 |
| RPL36 | ribosomal protein L36 | 0.0139413 |
| PGK1 | phosphoglycerate kinase 1 | 0.0139227 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.013822 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0138188 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0137292 |
| PCED1B | PC-esterase domain containing 1B | 0.0135949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.233841 |
| PM20D1 | peptidase M20 domain containing 1 | -0.226052 |
| GRAMD1B | GRAM domain containing 1B | -0.174773 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.111971 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.10409 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0946688 |
| RPS2 | ribosomal protein S2 | -0.0795017 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0785929 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0784038 |
| ASPH | aspartate beta-hydroxylase | -0.0719809 |
| WWOX | WW domain containing oxidoreductase | -0.0683739 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0676852 |
| KIF5B | kinesin family member 5B | -0.0546395 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0541279 |
| TXNRD1 | thioredoxin reductase 1 | -0.0541074 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0526575 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0516575 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0515005 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0506137 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0504193 |
| RTN4 | reticulon 4 | -0.0500817 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0485917 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0480335 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0469108 |
| FGB | fibrinogen beta chain | -0.0460842 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0444488 |
| IER3 | immediate early response 3 | -0.0432134 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0413191 |
| RBM39 | RNA binding motif protein 39 | -0.0412417 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0404619 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0378356 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0370875 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0357582 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0356665 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.034769 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0345004 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0337143 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0333297 |
| PFDN2 | prefoldin subunit 2 | -0.0332449 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0326895 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0322153 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0318267 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0318249 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0314184 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0306633 |
| BMP6 | bone morphogenetic protein 6 | -0.0303855 |
| CLTC | clathrin, heavy chain (Hc) | -0.0302498 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0301577 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0301163 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0299507 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0294312 |
| RPL19 | ribosomal protein L19 | -0.0283537 |
| RPS6 | ribosomal protein S6 | -0.0282673 |
| RPS12 | ribosomal protein S12 | -0.0282529 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0278686 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0275747 |
| SMAD3 | SMAD family member 3 | -0.0274947 |
| GOLT1B | golgi transport 1B | -0.0273499 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0271668 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.026795 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0266614 |
| NCKAP1 | NCK-associated protein 1 | -0.0266143 |
| USP34 | ubiquitin specific peptidase 34 | -0.0265683 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0261494 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0260306 |
| TNPO1 | transportin 1 | -0.0259467 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0258149 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0257482 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0255825 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0254414 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0253959 |
| PAPOLA | poly(A) polymerase alpha | -0.0252843 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0251339 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0251217 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0251024 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0248201 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0247916 |
| EXOC6B | exocyst complex component 6B | -0.0243514 |
| SQSTM1 | sequestosome 1 | -0.0243089 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0233309 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.023277 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0232246 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0230938 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0230871 |
| CCNY | cyclin Y | -0.0229089 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.022425 |
| DENND4A | DENN/MADD domain containing 4A | -0.0223859 |
| BRD2 | bromodomain containing 2 | -0.0222641 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0222334 |
| SMYD3 | SET and MYND domain containing 3 | -0.0220218 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0219513 |
| RECQL | RecQ helicase-like | -0.0218462 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0217123 |
| CANX | calnexin | -0.0216053 |
| MATR3 | matrin 3 | -0.0215903 |
| STC1 | stanniocalcin 1 | -0.0212984 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0212382 |
| YBX3 | Y box binding protein 3 | -0.0211625 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0211501 |
