| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.177707 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0939139 |
| INHBA | inhibin, beta A | 0.0908432 |
| STC1 | stanniocalcin 1 | 0.089791 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0850268 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0829106 |
| RPLP1 | ribosomal protein, large, P1 | 0.074107 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0666469 |
| NDRG1 | N-myc downstream regulated 1 | 0.0666371 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0654996 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0610288 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0608724 |
| DSCAM | Down syndrome cell adhesion molecule | 0.060018 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.05938 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0566321 |
| ZNF292 | zinc finger protein 292 | 0.0561065 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0535097 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0520528 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0495469 |
| EGFR | epidermal growth factor receptor | 0.0492291 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0477245 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0476573 |
| FNIP1 | folliculin interacting protein 1 | 0.0470897 |
| RNF145 | ring finger protein 145 | 0.0459879 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0453871 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0452432 |
| FN1 | fibronectin 1 | 0.0449025 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0442531 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0432188 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0428044 |
| KIF5B | kinesin family member 5B | 0.0415818 |
| PRKCA | protein kinase C, alpha | 0.0415341 |
| DTNA | dystrobrevin, alpha | 0.0405852 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0403365 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398416 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0389766 |
| RLF | rearranged L-myc fusion | 0.0385686 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038461 |
| RASA2 | RAS p21 protein activator 2 | 0.0383345 |
| GOLGA4 | golgin A4 | 0.0381218 |
| ZNF207 | zinc finger protein 207 | 0.0379138 |
| EFNA5 | ephrin-A5 | 0.0378918 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0378516 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0376212 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0375306 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0372879 |
| TPM3 | tropomyosin 3 | 0.0371171 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0370192 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0357276 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0356506 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0354831 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0350874 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0347953 |
| ENO1 | enolase 1, (alpha) | 0.0343845 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0340863 |
| FAM168A | family with sequence similarity 168, member A | 0.034062 |
| PARD3 | par-3 family cell polarity regulator | 0.0336079 |
| NBAS | neuroblastoma amplified sequence | 0.0331899 |
| FMNL2 | formin-like 2 | 0.032997 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0329441 |
| YEATS2 | YEATS domain containing 2 | 0.0325088 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0323948 |
| FAM13A | family with sequence similarity 13, member A | 0.0322583 |
| TXNRD1 | thioredoxin reductase 1 | 0.0320758 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0320238 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0316321 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.031019 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0310172 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0309039 |
| RPS3 | ribosomal protein S3 | 0.0305872 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0302934 |
| DENND4A | DENN/MADD domain containing 4A | 0.0299074 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0297976 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0295562 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.029452 |
| USP3 | ubiquitin specific peptidase 3 | 0.0292599 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0289054 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287706 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0281427 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0281228 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.028082 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.028034 |
| MYO1B | myosin IB | 0.0277721 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0275932 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0272147 |
| RORA | RAR-related orphan receptor A | 0.0270753 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.02707 |
| NGLY1 | N-glycanase 1 | 0.0270587 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0268541 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0267127 |
| TJP1 | tight junction protein 1 | 0.0266823 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0265427 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0265129 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0264881 |
| AK1 | adenylate kinase 1 | 0.0264792 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0264194 |
| RAB10 | RAB10, member RAS oncogene family | 0.0264018 |
| OGA | O-GlcNAcase | 0.026332 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0263055 |
| CCNY | cyclin Y | 0.0262511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | -0.0952194 |
| FTL | ferritin, light polypeptide | -0.0910826 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0848656 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0782542 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0747116 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0732853 |
| SRPK2 | SRSF protein kinase 2 | -0.0627808 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0626625 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0575885 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0566677 |
| ATXN1 | ataxin 1 | -0.0562326 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0540617 |
| ANXA1 | annexin A1 | -0.0532072 |
| TMEM123 | transmembrane protein 123 | -0.0525583 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0522335 |
| TXNIP | thioredoxin interacting protein | -0.0510566 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0506537 |
| POTEF | POTE ankyrin domain family, member F | -0.050152 |
| RUNX1 | runt-related transcription factor 1 | -0.0489693 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0475357 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0457841 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0455635 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0455396 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0453469 |
| SQSTM1 | sequestosome 1 | -0.0436239 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0430479 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.04256 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0423129 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0422228 |
| MYO6 | myosin VI | -0.0421248 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0414941 |
| MSI2 | musashi RNA-binding protein 2 | -0.0411319 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0408031 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0398861 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0397543 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0396559 |
| MTPN | myotrophin | -0.0393025 |
| GDF15 | growth differentiation factor 15 | -0.0383329 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0382016 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0380837 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0379765 |
| RPL11 | ribosomal protein L11 | -0.0378397 |
| RPL23 | ribosomal protein L23 | -0.0377973 |
| PERP | PERP, TP53 apoptosis effector | -0.0376462 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0376428 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0373582 |
| NBEAL1 | neurobeachin-like 1 | -0.0365494 |
| RPS16 | ribosomal protein S16 | -0.0364732 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0360596 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0359999 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0359461 |
| YME1L1 | YME1-like 1 ATPase | -0.0358975 |
| CCDC6 | coiled-coil domain containing 6 | -0.0352035 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0350342 |
| TOP1 | topoisomerase (DNA) I | -0.0348774 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0348152 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0344329 |
| CLTC | clathrin, heavy chain (Hc) | -0.0342504 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0340364 |
| YAP1 | Yes-associated protein 1 | -0.0335904 |
| PTGES2 | prostaglandin E synthase 2 | -0.0335893 |
| CUL1 | cullin 1 | -0.0334403 |
| RPL9 | ribosomal protein L9 | -0.0330063 |
| RPL35A | ribosomal protein L35a | -0.0329751 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0329244 |
| ATOSA | atos homolog A | -0.0325583 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.032468 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0322152 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0316907 |
| CYTH1 | cytohesin 1 | -0.0316159 |
| ATP11B | ATPase, class VI, type 11B | -0.0312129 |
| S100A9 | S100 calcium binding protein A9 | -0.0311046 |
| RPS4X | ribosomal protein S4, X-linked | -0.0310063 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0310053 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0310013 |
| GLCCI1 | glucocorticoid induced 1 | -0.0306643 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0305387 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0304449 |
| PTMA | prothymosin, alpha | -0.0303676 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0302465 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0297984 |
| NPTN | neuroplastin | -0.0296735 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0295078 |
| UBAP1 | ubiquitin associated protein 1 | -0.0294368 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0293792 |
| SLMAP | sarcolemma associated protein | -0.0293188 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0292582 |
| S100A6 | S100 calcium binding protein A6 | -0.0290726 |
| TAOK3 | TAO kinase 3 | -0.0290346 |
| MX1 | MX dynamin-like GTPase 1 | -0.029033 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.028862 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0286919 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0285787 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0285727 |
| LAMB1 | laminin, beta 1 | -0.028406 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0283065 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0278324 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0277619 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0276634 |
| RPS6 | ribosomal protein S6 | -0.0276221 |
