| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.305459 |
| VIM | vimentin | 0.117612 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0989061 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.063754 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0560537 |
| OSMR | oncostatin M receptor | 0.0538008 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0527624 |
| TMSB10 | thymosin beta 10 | 0.0491795 |
| HMGA2 | high mobility group AT-hook 2 | 0.0462497 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0452804 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0452503 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0449683 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0428325 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0424641 |
| H1-0 | H1.0 linker histone | 0.0410576 |
| RAD51B | RAD51 paralog B | 0.0408024 |
| SMAD3 | SMAD family member 3 | 0.0405779 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0385792 |
| RPL35A | ribosomal protein L35a | 0.0377217 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0373414 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0370532 |
| AHNAK | AHNAK nucleoprotein | 0.0366842 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0341727 |
| RPL13A | ribosomal protein L13a | 0.0341034 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0322591 |
| EGFR | epidermal growth factor receptor | 0.0321867 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0321417 |
| FMNL2 | formin-like 2 | 0.0319687 |
| EXOC4 | exocyst complex component 4 | 0.0319236 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0310953 |
| RPL34 | ribosomal protein L34 | 0.0310634 |
| RPL8 | ribosomal protein L8 | 0.0309359 |
| MAP4 | microtubule-associated protein 4 | 0.0298983 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0286749 |
| PFN1 | profilin 1 | 0.0286669 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0284669 |
| RPS8 | ribosomal protein S8 | 0.0274907 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0273032 |
| RPL11 | ribosomal protein L11 | 0.0272727 |
| RPS3 | ribosomal protein S3 | 0.0269235 |
| DENND1A | DENN/MADD domain containing 1A | 0.0268662 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0262904 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0262815 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0262209 |
| ATG7 | autophagy related 7 | 0.0260702 |
| PDE10A | phosphodiesterase 10A | 0.0259196 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0253359 |
| RPS14 | ribosomal protein S14 | 0.0251601 |
| GNAS | GNAS complex locus | 0.0248157 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0247464 |
| VCL | vinculin | 0.0247284 |
| KIAA1328 | KIAA1328 | 0.0241057 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0238497 |
| RPS4X | ribosomal protein S4, X-linked | 0.0234231 |
| RPL35 | ribosomal protein L35 | 0.0231576 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0229416 |
| SFTPA2 | surfactant protein A2 | 0.0229035 |
| LOXL2 | lysyl oxidase-like 2 | 0.0227159 |
| RNF213 | ring finger protein 213 | 0.0226341 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222314 |
| ATXN1 | ataxin 1 | 0.0219578 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0216456 |
| PGK1 | phosphoglycerate kinase 1 | 0.021471 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0213099 |
| TMEM131 | transmembrane protein 131 | 0.0211827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0211673 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0211118 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0209912 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0208337 |
| COPA | coatomer protein complex, subunit alpha | 0.0207623 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0206499 |
| RYR3 | ryanodine receptor 3 | 0.0206322 |
| RPL37A | ribosomal protein L37a | 0.0201957 |
| RPS27A | ribosomal protein S27a | 0.0198769 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0193935 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0192686 |
| FNBP4 | formin binding protein 4 | 0.0191712 |
| TUBB | tubulin, beta class I | 0.0190627 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.018889 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0187811 |
| RPS20 | ribosomal protein S20 | 0.0186657 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0185588 |
| CLIC1 | chloride intracellular channel 1 | 0.0185357 |
| RPL32 | ribosomal protein L32 | 0.0181601 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0179515 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0178546 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0178035 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0175362 |
| KLF6 | Kruppel-like factor 6 | 0.0173413 |
| EGR1 | early growth response 1 | 0.0171345 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0171096 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0169697 |
| PHF14 | PHD finger protein 14 | 0.0169019 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0168614 |
| RPS21 | ribosomal protein S21 | 0.0168253 |
| PHF21A | PHD finger protein 21A | 0.0167933 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0167759 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0167391 |
| FAM13A | family with sequence similarity 13, member A | 0.0166596 |
| RPS27 | ribosomal protein S27 | 0.0164904 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.223132 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.108904 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0849066 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0847486 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0650733 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0641017 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0590822 |
| TXNRD1 | thioredoxin reductase 1 | -0.0571191 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.056329 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0540859 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0536755 |
| YBX3 | Y box binding protein 3 | -0.0525667 |
| RTN4 | reticulon 4 | -0.0509888 |
| BRD2 | bromodomain containing 2 | -0.0500953 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0452143 |
| RPS2 | ribosomal protein S2 | -0.0438911 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0429384 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0413934 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0410965 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0401235 |
| XPO1 | exportin 1 | -0.039149 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0384068 |
| STK4 | serine/threonine kinase 4 | -0.0379751 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.037909 |
| TPI1 | triosephosphate isomerase 1 | -0.037904 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0377048 |
| PCBP2 | poly(rC) binding protein 2 | -0.0374193 |
| CLTC | clathrin, heavy chain (Hc) | -0.0370462 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0348522 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0341325 |
| DENR | density-regulated protein | -0.0320019 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0317945 |
| SEPTIN7 | septin 7 | -0.0315027 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0313509 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0307974 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.030114 |
| RAB10 | RAB10, member RAS oncogene family | -0.0298803 |
| MKI67 | marker of proliferation Ki-67 | -0.0292733 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0290803 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0285274 |
| PHIP | pleckstrin homology domain interacting protein | -0.0284048 |
| PLCB4 | phospholipase C, beta 4 | -0.0284016 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0282693 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0282475 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0281048 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0271995 |
| ZNF638 | zinc finger protein 638 | -0.0269941 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0269772 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0268414 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0265277 |
| PKM | pyruvate kinase, muscle | -0.0263797 |
| ANO6 | anoctamin 6 | -0.0263119 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0259992 |
| MORF4L2 | mortality factor 4 like 2 | -0.0259373 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0258968 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0257623 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0257286 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0251869 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0249954 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0247844 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0247273 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0246445 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0245396 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0243402 |
| GPHN | gephyrin | -0.0240159 |
| IPO7 | importin 7 | -0.0239607 |
| PCM1 | pericentriolar material 1 | -0.0238697 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0238169 |
| RECQL | RecQ helicase-like | -0.0237435 |
| MED13L | mediator complex subunit 13-like | -0.0237022 |
| ADAR | adenosine deaminase, RNA-specific | -0.0235784 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0235744 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0235695 |
| TUBA1B | tubulin, alpha 1b | -0.0234911 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0232006 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0231991 |
| SPAG9 | sperm associated antigen 9 | -0.0229753 |
| UBN2 | ubinuclein 2 | -0.022894 |
| BBX | bobby sox homolog (Drosophila) | -0.0228501 |
| PNN | pinin, desmosome associated protein | -0.0228379 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0228014 |
| UBC | ubiquitin C | -0.0226051 |
| WDR45B | WD repeat domain 45B | -0.0225689 |
| MTPN | myotrophin | -0.022559 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0224042 |
| OGA | O-GlcNAcase | -0.0223752 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0222105 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.022103 |
| RRM2 | ribonucleotide reductase M2 | -0.0219547 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0218315 |
| ETNK1 | ethanolamine kinase 1 | -0.0217707 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0217389 |
| GPSM2 | G-protein signaling modulator 2 | -0.0215752 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0213707 |
| CEP192 | centrosomal protein 192kDa | -0.0213574 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0212549 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0210094 |
| EXOC6B | exocyst complex component 6B | -0.0208527 |
| SETD5 | SET domain containing 5 | -0.0208168 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0205578 |
