| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.19449 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.148455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.103515 |
| VIM | vimentin | 0.0909588 |
| PTMA | prothymosin, alpha | 0.0891031 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.085276 |
| TMSB10 | thymosin beta 10 | 0.0841963 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0760932 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0715809 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0662573 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0646391 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0623992 |
| FN1 | fibronectin 1 | 0.058474 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0523551 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0515505 |
| RPL35A | ribosomal protein L35a | 0.0493053 |
| FTL | ferritin, light polypeptide | 0.048892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0470519 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0456418 |
| SPAG9 | sperm associated antigen 9 | 0.043056 |
| PGK1 | phosphoglycerate kinase 1 | 0.0428125 |
| B2M | beta-2-microglobulin | 0.0418508 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0416129 |
| RPS8 | ribosomal protein S8 | 0.0400086 |
| S100A6 | S100 calcium binding protein A6 | 0.0396744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0394751 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0394273 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0387739 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0383238 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.038273 |
| S100A10 | S100 calcium binding protein A10 | 0.036383 |
| OGA | O-GlcNAcase | 0.0357877 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0356493 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0349839 |
| GNAS | GNAS complex locus | 0.034978 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0348117 |
| CANX | calnexin | 0.0337768 |
| RPL23 | ribosomal protein L23 | 0.0325724 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0320666 |
| RAI1 | retinoic acid induced 1 | 0.0317674 |
| RPL12 | ribosomal protein L12 | 0.0315088 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0312583 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0309349 |
| PFN1 | profilin 1 | 0.030783 |
| FAM13A | family with sequence similarity 13, member A | 0.030473 |
| RPLP1 | ribosomal protein, large, P1 | 0.0303507 |
| RPS4X | ribosomal protein S4, X-linked | 0.028907 |
| RPL19 | ribosomal protein L19 | 0.0285916 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0282688 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0277962 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0276454 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0275441 |
| CALR | calreticulin | 0.0275155 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0274979 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0273747 |
| RPS12 | ribosomal protein S12 | 0.0262889 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262029 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0258355 |
| RPS14 | ribosomal protein S14 | 0.0258106 |
| GOLGA4 | golgin A4 | 0.0257946 |
| RPL8 | ribosomal protein L8 | 0.025338 |
| RPLP0 | ribosomal protein, large, P0 | 0.0251186 |
| HLA-A | major histocompatibility complex, class I, A | 0.0248231 |
| RPL34 | ribosomal protein L34 | 0.0242605 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0233032 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0231266 |
| INHBA | inhibin, beta A | 0.0229087 |
| YBX1 | Y box binding protein 1 | 0.0228989 |
| RPL11 | ribosomal protein L11 | 0.022708 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0225765 |
| LMNA | lamin A/C | 0.0225661 |
| ZNF292 | zinc finger protein 292 | 0.0220109 |
| RPS19 | ribosomal protein S19 | 0.0218751 |
| IL6 | interleukin 6 | 0.0214967 |
| RPS6 | ribosomal protein S6 | 0.0214173 |
| RPS27A | ribosomal protein S27a | 0.0212184 |
| HELZ | helicase with zinc finger | 0.0209324 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0204853 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.020119 |
| COPA | coatomer protein complex, subunit alpha | 0.0200711 |
| RPS27 | ribosomal protein S27 | 0.020018 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0200179 |
| PRKD3 | protein kinase D3 | 0.0199752 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0193827 |
| RPL13A | ribosomal protein L13a | 0.019214 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0191737 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0191683 |
| RPS23 | ribosomal protein S23 | 0.0191338 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0190285 |
| PCBP2 | poly(rC) binding protein 2 | 0.0190017 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0189118 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.018862 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0186367 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.018629 |
| CBX3 | chromobox homolog 3 | 0.0186255 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.018598 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0185955 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0185796 |
| RPL18 | ribosomal protein L18 | 0.0184875 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0182818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.144147 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.131108 |
| GRAMD1B | GRAM domain containing 1B | -0.110817 |
| GDA | guanine deaminase | -0.107492 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0954837 |
| EFNA5 | ephrin-A5 | -0.080403 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0801107 |
| PDLIM5 | PDZ and LIM domain 5 | -0.079128 |
| KYNU | kynureninase | -0.0561415 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0520546 |
| TXNRD1 | thioredoxin reductase 1 | -0.0491678 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0446332 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0442935 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0431349 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0424313 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0419241 |
| PCBP3 | poly(rC) binding protein 3 | -0.0410296 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0401508 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0389236 |
| ASPH | aspartate beta-hydroxylase | -0.037308 |
| DST | dystonin | -0.0365157 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0353258 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0346102 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0343286 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0342087 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0337959 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0335075 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0325758 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0319313 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0315245 |
| MYOF | myoferlin | -0.0303459 |
| AUTS2 | autism susceptibility candidate 2 | -0.0298437 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.02983 |
| RPS2 | ribosomal protein S2 | -0.0295125 |
| CDH13 | cadherin 13 | -0.029442 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0289388 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0279439 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0265703 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0262394 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.026046 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0257816 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.025208 |
| GLIS3 | GLIS family zinc finger 3 | -0.0251058 |
| NRCAM | neuronal cell adhesion molecule | -0.0247161 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0246035 |
| CLTC | clathrin, heavy chain (Hc) | -0.0241734 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0239995 |
| ALPK2 | alpha-kinase 2 | -0.0238635 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0237866 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0237417 |
| PLCB4 | phospholipase C, beta 4 | -0.0236527 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0236079 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0234103 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0233221 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0232565 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0225477 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0225434 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0219308 |
| TBXT | T-box transcription factor T | -0.0218671 |
| FMNL2 | formin-like 2 | -0.0217922 |
| TUSC3 | tumor suppressor candidate 3 | -0.0216749 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0215342 |
| RAD51B | RAD51 paralog B | -0.0213278 |
| SMYD3 | SET and MYND domain containing 3 | -0.0211052 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0210509 |
| INTS6 | integrator complex subunit 6 | -0.0203715 |
| RGS2 | regulator of G-protein signaling 2 | -0.0195716 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0192769 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0190203 |
| CTSL | cathepsin L | -0.0187591 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0186914 |
| FLNB | filamin B, beta | -0.0186878 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0186695 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0181382 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0179884 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0179847 |
| RAB10 | RAB10, member RAS oncogene family | -0.0179818 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0177639 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.017752 |
| RPS18 | ribosomal protein S18 | -0.0172999 |
| BMP6 | bone morphogenetic protein 6 | -0.0169994 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0169551 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0169501 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0169301 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0168014 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0165114 |
| NTN4 | netrin 4 | -0.0164972 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0163796 |
| PRRC2B | proline-rich coiled-coil 2B | -0.016345 |
| TNPO1 | transportin 1 | -0.0163447 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0162949 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0161931 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0161153 |
| BDNF | brain-derived neurotrophic factor | -0.0161011 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0160639 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0159564 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0159277 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0158416 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0157356 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0155825 |
