| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0668722 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0566785 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0457568 |
| QKI | QKI, KH domain containing, RNA binding | 0.0448901 |
| ZNF292 | zinc finger protein 292 | 0.0409823 |
| FBXO11 | F-box protein 11 | 0.0408276 |
| RPS2 | ribosomal protein S2 | 0.0399008 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0394587 |
| RLF | rearranged L-myc fusion | 0.0393784 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0382824 |
| PFN1 | profilin 1 | 0.0368703 |
| JMJD1C | jumonji domain containing 1C | 0.0353188 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0350438 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0346489 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0341644 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0326197 |
| CDC73 | cell division cycle 73 | 0.0316423 |
| FOXG1 | forkhead box G1 | 0.0315899 |
| MTF2 | metal response element binding transcription factor 2 | 0.0315245 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0312311 |
| TLK1 | tousled-like kinase 1 | 0.0295896 |
| WBP11 | WW domain binding protein 11 | 0.0291275 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0291108 |
| RPL28 | ribosomal protein L28 | 0.0286058 |
| NEK7 | NIMA-related kinase 7 | 0.0277675 |
| NOP58 | NOP58 ribonucleoprotein | 0.0274922 |
| SRP54 | signal recognition particle 54kDa | 0.0274112 |
| FERMT2 | fermitin family member 2 | 0.0272881 |
| RPS6 | ribosomal protein S6 | 0.0270702 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0262637 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0262406 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0259085 |
| SFTPA2 | surfactant protein A2 | 0.0256917 |
| TMEM64 | transmembrane protein 64 | 0.0252358 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0252217 |
| PARD3 | par-3 family cell polarity regulator | 0.0252002 |
| DENND4C | DENN/MADD domain containing 4C | 0.0250209 |
| WTAP | Wilms tumor 1 associated protein | 0.0248625 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0248304 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0247737 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0244334 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0243512 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0242549 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0241188 |
| HMGA2 | high mobility group AT-hook 2 | 0.0239516 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0236805 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.023485 |
| ZFP36 | ZFP36 ring finger protein | 0.0232731 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0231462 |
| USP3 | ubiquitin specific peptidase 3 | 0.0230299 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0229851 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0229348 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0228551 |
| PDS5B | PDS5 cohesin associated factor B | 0.0226364 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0225424 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0225317 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0225048 |
| RBM39 | RNA binding motif protein 39 | 0.0224899 |
| ASPH | aspartate beta-hydroxylase | 0.0222836 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0222541 |
| PDS5A | PDS5 cohesin associated factor A | 0.0219293 |
| FNBP1L | formin binding protein 1-like | 0.0218299 |
| HDAC9 | histone deacetylase 9 | 0.0216707 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.0211431 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0209287 |
| NCKAP1 | NCK-associated protein 1 | 0.0207634 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.020745 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0205954 |
| RAB10 | RAB10, member RAS oncogene family | 0.0205704 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0205624 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0204963 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0203371 |
| CCNL1 | cyclin L1 | 0.0201853 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0201269 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0199684 |
| NUP58 | nucleoporin 58 | 0.019926 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0199074 |
| PUM1 | pumilio RNA-binding family member 1 | 0.019747 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0196855 |
| SLMAP | sarcolemma associated protein | 0.0196589 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0196407 |
| SNX2 | sorting nexin 2 | 0.0195019 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0194752 |
| MEMO1 | mediator of cell motility 1 | 0.0192596 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0191654 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0191243 |
| NPR2 | natriuretic peptide receptor 2 | 0.0190329 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.0189603 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0188662 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0187393 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0187226 |
| GOLGA4 | golgin A4 | 0.0186998 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0185905 |
| FAM13A | family with sequence similarity 13, member A | 0.0185875 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.018499 |
| PAPOLA | poly(A) polymerase alpha | 0.0184664 |
| TXNL1 | thioredoxin-like 1 | 0.0183263 |
| NDRG1 | N-myc downstream regulated 1 | 0.0183159 |
| PRR16 | proline rich 16 | 0.0182075 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.018206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.18479 |
| COL11A1 | collagen, type XI, alpha 1 | -0.16833 |
| VIM | vimentin | -0.153457 |
| CADM2 | cell adhesion molecule 2 | -0.134903 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.116758 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.108975 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.105127 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0891062 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0859353 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0762705 |
| PTMA | prothymosin, alpha | -0.0739599 |
| PCDH9 | protocadherin 9 | -0.0704389 |
| ENO1 | enolase 1, (alpha) | -0.0666701 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0663134 |
| GPC3 | glypican 3 | -0.0646644 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0634266 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0615249 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0601118 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0595537 |
| MKI67 | marker of proliferation Ki-67 | -0.0567426 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0558613 |
| HMGB2 | high mobility group box 2 | -0.055393 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0546376 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0531331 |
| TENM3 | teneurin transmembrane protein 3 | -0.0527877 |
| UBC | ubiquitin C | -0.0507702 |
| CENPF | centromere protein F, 350/400kDa | -0.0499226 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0495343 |
| PEG10 | paternally expressed 10 | -0.0489668 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0489058 |
| APP | amyloid beta (A4) precursor protein | -0.0478711 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0476349 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0469968 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.046366 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0444279 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.043798 |
| RPS27A | ribosomal protein S27a | -0.0436059 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0429384 |
| COL3A1 | collagen, type III, alpha 1 | -0.0426429 |
| TPR | translocated promoter region, nuclear basket protein | -0.0425683 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0419144 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0415404 |
| CALR | calreticulin | -0.0410275 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0409194 |
| COL5A2 | collagen, type V, alpha 2 | -0.0405667 |
| GSE1 | Gse1 coiled-coil protein | -0.0391833 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0391631 |
| CENPE | centromere protein E, 312kDa | -0.0388092 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0386532 |
| COL1A2 | collagen, type I, alpha 2 | -0.0383149 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0378214 |
| LDHA | lactate dehydrogenase A | -0.0365825 |
| XPO1 | exportin 1 | -0.036366 |
| POTEF | POTE ankyrin domain family, member F | -0.0358838 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0351762 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0350595 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0346432 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0346059 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0339863 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0336799 |
| CALU | calumenin | -0.0319821 |
| RPS16 | ribosomal protein S16 | -0.0319688 |
| STMN1 | stathmin 1 | -0.0318953 |
| TMSB4X | thymosin beta 4, X-linked | -0.0317622 |
| APOE | apolipoprotein E | -0.0316905 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0316378 |
| RPS5 | ribosomal protein S5 | -0.0312411 |
| CKAP5 | cytoskeleton associated protein 5 | -0.031179 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0311154 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0311128 |
| RAI1 | retinoic acid induced 1 | -0.0309207 |
| TPX2 | TPX2, microtubule-associated | -0.0308448 |
| PGK1 | phosphoglycerate kinase 1 | -0.0308134 |
| RPL23 | ribosomal protein L23 | -0.030776 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0304637 |
| TEX11 | testis expressed 11 | -0.0300821 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0300601 |
| PCDH7 | protocadherin 7 | -0.0296545 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0289343 |
| MEIS2 | Meis homeobox 2 | -0.0289133 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0286548 |
| ACTG1 | actin gamma 1 | -0.0286041 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.02848 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0283616 |
| THBS1 | thrombospondin 1 | -0.0279819 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0277808 |
| SET | SET nuclear proto-oncogene | -0.027257 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0271016 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0269254 |
| ZFHX4 | zinc finger homeobox 4 | -0.0261554 |
| KIF4A | kinesin family member 4A | -0.026141 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0260289 |
| TRERF1 | transcriptional regulating factor 1 | -0.0259379 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0257896 |
| ANK2 | ankyrin 2, neuronal | -0.0255676 |
| SGO2 | shugoshin 2 | -0.0255499 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0252651 |
| PRELID2 | PRELI domain containing 2 | -0.0251572 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0250556 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0250169 |
