| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.135736 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.116447 |
| VCL | vinculin | 0.11104 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0675702 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0665735 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0661449 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0660647 |
| GOLGA4 | golgin A4 | 0.0618303 |
| FLNB | filamin B, beta | 0.0603848 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0587582 |
| JMJD1C | jumonji domain containing 1C | 0.0575848 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0562478 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0544194 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0531626 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0528241 |
| PYGB | phosphorylase, glycogen; brain | 0.0496978 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0466799 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0465312 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0465135 |
| FOXP1 | forkhead box P1 | 0.045492 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0443842 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0441536 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0425258 |
| RBM39 | RNA binding motif protein 39 | 0.0417497 |
| GPHN | gephyrin | 0.0412247 |
| HDAC9 | histone deacetylase 9 | 0.0406306 |
| NF1 | neurofibromin 1 | 0.0402673 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0402075 |
| ZNF292 | zinc finger protein 292 | 0.0394355 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.038968 |
| SETD5 | SET domain containing 5 | 0.0389678 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0375973 |
| PARD3 | par-3 family cell polarity regulator | 0.0372997 |
| PFN1 | profilin 1 | 0.0350213 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.034852 |
| PTK2 | protein tyrosine kinase 2 | 0.0345744 |
| EVI5 | ecotropic viral integration site 5 | 0.0340087 |
| EGFR | epidermal growth factor receptor | 0.033858 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0331754 |
| EFNA5 | ephrin-A5 | 0.0328116 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0323709 |
| TJP1 | tight junction protein 1 | 0.0320551 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0318332 |
| NBEA | neurobeachin | 0.03174 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316592 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0316142 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0315894 |
| RTN4 | reticulon 4 | 0.0315069 |
| DUSP4 | dual specificity phosphatase 4 | 0.031504 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0311935 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0311366 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0307977 |
| AHNAK | AHNAK nucleoprotein | 0.0304758 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.030358 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0302686 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0296628 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0292908 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0292675 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0292243 |
| SBF2 | SET binding factor 2 | 0.0289027 |
| DIAPH3 | diaphanous-related formin 3 | 0.0288296 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0286444 |
| MKI67 | marker of proliferation Ki-67 | 0.028588 |
| BMP2K | BMP2 inducible kinase | 0.0285105 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0284693 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284562 |
| TNRC6B | trinucleotide repeat containing 6B | 0.028453 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283138 |
| NUP58 | nucleoporin 58 | 0.0281792 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0280184 |
| SLMAP | sarcolemma associated protein | 0.0280107 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0276494 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0274896 |
| TCF12 | transcription factor 12 | 0.0274875 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.02723 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0271937 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0269804 |
| QKI | QKI, KH domain containing, RNA binding | 0.0269751 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0267796 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0267583 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266328 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0260957 |
| GLI3 | GLI family zinc finger 3 | 0.0260704 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0256902 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0256861 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0256845 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0253876 |
| YAP1 | Yes-associated protein 1 | 0.0252477 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0252032 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0251586 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0251511 |
| TLK1 | tousled-like kinase 1 | 0.0250442 |
| TXNRD1 | thioredoxin reductase 1 | 0.024838 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0247105 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0246087 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0243589 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0241811 |
| ABHD12 | abhydrolase domain containing 12 | 0.024043 |
| ECT2 | epithelial cell transforming 2 | 0.0239824 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0238109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | -0.113642 |
| PTMA | prothymosin, alpha | -0.0441133 |
| PKM | pyruvate kinase, muscle | -0.0416476 |
| RPL35A | ribosomal protein L35a | -0.040739 |
| TMSB4X | thymosin beta 4, X-linked | -0.0349687 |
| RPL4 | ribosomal protein L4 | -0.0327429 |
| S100A6 | S100 calcium binding protein A6 | -0.0305865 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0291355 |
| ACTG1 | actin gamma 1 | -0.0258666 |
| LDHA | lactate dehydrogenase A | -0.0200364 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0199299 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179075 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0172834 |
| TMSB10 | thymosin beta 10 | -0.016375 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0161584 |
| MT2A | metallothionein 2A | -0.0152866 |
| RPL18 | ribosomal protein L18 | -0.0152001 |
| RPL7A | ribosomal protein L7a | -0.0143104 |
| RPLP2 | ribosomal protein, large, P2 | -0.0136229 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0135523 |
| RPL26 | ribosomal protein L26 | -0.0125042 |
| RPL9 | ribosomal protein L9 | -0.0124222 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0123702 |
| RPS19 | ribosomal protein S19 | -0.0120132 |
| RPS4X | ribosomal protein S4, X-linked | -0.0119371 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0116839 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0113925 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0113446 |
| RPS24 | ribosomal protein S24 | -0.0111583 |
| FBLN2 | fibulin 2 | -0.0107392 |
| SQSTM1 | sequestosome 1 | -0.0106244 |
| RPL31 | ribosomal protein L31 | -0.0102713 |
| TPM4 | tropomyosin 4 | -0.0100142 |
| RACK1 | receptor for activated C kinase 1 | -0.00994219 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.00969018 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00956573 |
| RPL23 | ribosomal protein L23 | -0.00900441 |
| PRDX2 | peroxiredoxin 2 | -0.00889526 |
| IRS1 | insulin receptor substrate 1 | -0.00886295 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.008855 |
| RPL13A | ribosomal protein L13a | -0.00883614 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0087742 |
| RPS27 | ribosomal protein S27 | -0.00874872 |
| RPS25 | ribosomal protein S25 | -0.00867402 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.00862337 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.00859214 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.00858395 |
| AXIN1 | axin 1 | -0.00848702 |
| DHPS | deoxyhypusine synthase | -0.00834112 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.008262 |
| GOLGA3 | golgin A3 | -0.00817684 |
| ZNF608 | zinc finger protein 608 | -0.00806272 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.00777117 |
| MT1X | metallothionein 1X | -0.00768359 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.00768033 |
| ANAPC16 | anaphase promoting complex subunit 16 | -0.00760295 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.00739048 |
| ILK | integrin-linked kinase | -0.00729821 |
| DENND2D | DENN/MADD domain containing 2D | -0.00723651 |
| RPS9 | ribosomal protein S9 | -0.0072093 |
| CCDC107 | coiled-coil domain containing 107 | -0.00719712 |
| FER1L6 | fer-1-like family member 6 | -0.00716197 |
| H1-4 | H1.4 linker histone, cluster member | -0.00715606 |
| CDC14A | cell division cycle 14A | -0.0071059 |
| RPS27A | ribosomal protein S27a | -0.00708522 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00706938 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.00704961 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00699273 |
| RAB13 | RAB13, member RAS oncogene family | -0.00699125 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00695016 |
| RPS12 | ribosomal protein S12 | -0.00693979 |
| ABCA10 | ATP-binding cassette, sub-family A (ABC1), member 10 | -0.00693698 |
| BRD2 | bromodomain containing 2 | -0.00687493 |
| MED6 | mediator complex subunit 6 | -0.00681211 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.00678817 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.00671104 |
| PHPT1 | phosphohistidine phosphatase 1 | -0.00660254 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.0065649 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00646787 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00634174 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00630197 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00622054 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.00621202 |
| HMGB2 | high mobility group box 2 | -0.00620013 |
| ERGIC3 | ERGIC and golgi 3 | -0.00618213 |
| PRMT2 | protein arginine methyltransferase 2 | -0.00617784 |
| CEP250 | centrosomal protein 250kDa | -0.00614725 |
| S100A4 | S100 calcium binding protein A4 | -0.00614248 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00613853 |
| HLA-A | major histocompatibility complex, class I, A | -0.00613025 |
| TUFM | Tu translation elongation factor, mitochondrial | -0.00611781 |
| RPS15 | ribosomal protein S15 | -0.00610297 |
| POLGARF | POLG alternative reading frame | -0.00610044 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00609059 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -0.00607914 |
| RPS11 | ribosomal protein S11 | -0.00605186 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) | -0.00602914 |
| GABARAP | GABA(A) receptor-associated protein | -0.00600327 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00597348 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0059544 |
