| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.148735 |
| VIM | vimentin | 0.0936916 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0762333 |
| SFTPA2 | surfactant protein A2 | 0.0761995 |
| PDE10A | phosphodiesterase 10A | 0.0701298 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0675179 |
| CD44 | CD44 molecule (Indian blood group) | 0.0671732 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0636745 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0566234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0563843 |
| DST | dystonin | 0.0548308 |
| FRMD4A | FERM domain containing 4A | 0.0530955 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0527302 |
| FNIP1 | folliculin interacting protein 1 | 0.0445804 |
| STC1 | stanniocalcin 1 | 0.0396144 |
| FN1 | fibronectin 1 | 0.0392094 |
| GOLGA4 | golgin A4 | 0.0391541 |
| CADM1 | cell adhesion molecule 1 | 0.0381579 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367705 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0364389 |
| VCAN | versican | 0.0363436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0363117 |
| RND3 | Rho family GTPase 3 | 0.035804 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0349381 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0338675 |
| GLIS3 | GLIS family zinc finger 3 | 0.0338491 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0337956 |
| KYNU | kynureninase | 0.03282 |
| JMJD1C | jumonji domain containing 1C | 0.0328188 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325477 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0324404 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0321399 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0317859 |
| NAV2 | neuron navigator 2 | 0.0314054 |
| ATP13A3 | ATPase type 13A3 | 0.0306245 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0297056 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0293939 |
| HDAC9 | histone deacetylase 9 | 0.0288358 |
| CDH13 | cadherin 13 | 0.0285397 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282717 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0281839 |
| RPS6 | ribosomal protein S6 | 0.02749 |
| ZNF292 | zinc finger protein 292 | 0.0274887 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0274161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.026938 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0269079 |
| RAI14 | retinoic acid induced 14 | 0.0268843 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0268215 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0265446 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0265124 |
| FLNB | filamin B, beta | 0.0263048 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0256919 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0254896 |
| ATXN1 | ataxin 1 | 0.0251979 |
| LOXL2 | lysyl oxidase-like 2 | 0.0249597 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0248302 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0248218 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0247694 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0243013 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0242871 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240043 |
| SPAG9 | sperm associated antigen 9 | 0.0237962 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0236247 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0236029 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0235389 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0235089 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0234263 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0234008 |
| UBC | ubiquitin C | 0.023098 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0230233 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0228161 |
| MMP12 | matrix metallopeptidase 12 | 0.022776 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0223692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0223691 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0223049 |
| EGFR | epidermal growth factor receptor | 0.0220894 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0220538 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0219758 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0219465 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0218978 |
| GOLGB1 | golgin B1 | 0.0218167 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0212456 |
| NDRG1 | N-myc downstream regulated 1 | 0.0212322 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0209747 |
| LOX | lysyl oxidase | 0.020825 |
| WTAP | Wilms tumor 1 associated protein | 0.0207373 |
| CENPF | centromere protein F, 350/400kDa | 0.0206022 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0205095 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0202892 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0202498 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0199133 |
| FMNL2 | formin-like 2 | 0.0197744 |
| CDK19 | cyclin-dependent kinase 19 | 0.0197555 |
| CLTC | clathrin, heavy chain (Hc) | 0.0196355 |
| STAG2 | stromal antigen 2 | 0.0195875 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0194971 |
| NGLY1 | N-glycanase 1 | 0.0194558 |
| SRGN | serglycin | 0.0192694 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0192643 |
| VEGFA | vascular endothelial growth factor A | 0.0192324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | -0.0730846 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0719206 |
| TMSB10 | thymosin beta 10 | -0.0594554 |
| MT2A | metallothionein 2A | -0.047689 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0428443 |
| HLA-B | major histocompatibility complex, class I, B | -0.0323756 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0293714 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0272327 |
| RPL35A | ribosomal protein L35a | -0.0214632 |
| RPLP1 | ribosomal protein, large, P1 | -0.0208613 |
| LDHA | lactate dehydrogenase A | -0.0203454 |
| ENO1 | enolase 1, (alpha) | -0.0198599 |
| FTL | ferritin, light polypeptide | -0.018664 |
| RPS24 | ribosomal protein S24 | -0.018068 |
| RPL23 | ribosomal protein L23 | -0.0161133 |
| MT1X | metallothionein 1X | -0.0145838 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.014373 |
| RPL4 | ribosomal protein L4 | -0.014118 |
| PKM | pyruvate kinase, muscle | -0.0140604 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0139914 |
| RPL26 | ribosomal protein L26 | -0.0137729 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0137458 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0130676 |
| BICC1 | BicC family RNA binding protein 1 | -0.0128963 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0127632 |
| IER2 | immediate early response 2 | -0.012418 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0121897 |
| RPS19 | ribosomal protein S19 | -0.0118129 |
| RPS5 | ribosomal protein S5 | -0.0116414 |
| CD63 | CD63 molecule | -0.011514 |
| EGR1 | early growth response 1 | -0.0113186 |
| RPL18 | ribosomal protein L18 | -0.0110918 |
| RPLP2 | ribosomal protein, large, P2 | -0.0109315 |
| SDC4 | syndecan 4 | -0.0105409 |
| RPL36 | ribosomal protein L36 | -0.0103645 |
| ACTG1 | actin gamma 1 | -0.0099941 |
| NCOA7 | nuclear receptor coactivator 7 | -0.00996601 |
| THBS1 | thrombospondin 1 | -0.00995992 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.00994463 |
| KRT19 | keratin 19, type I | -0.009849 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00961409 |
| RPS4X | ribosomal protein S4, X-linked | -0.00959171 |
| PTMA | prothymosin, alpha | -0.00947314 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.00922049 |
| RPS11 | ribosomal protein S11 | -0.00894641 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.00886245 |
| MORF4L2 | mortality factor 4 like 2 | -0.00849585 |
| KLF6 | Kruppel-like factor 6 | -0.00847151 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.00832837 |
| DUSP12 | dual specificity phosphatase 12 | -0.00827181 |
| HMGB2 | high mobility group box 2 | -0.00818132 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00815021 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00809145 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0078739 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00786231 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0078472 |
| APP | amyloid beta (A4) precursor protein | -0.00782754 |
| JUND | jun D proto-oncogene | -0.0077557 |
| RPL35 | ribosomal protein L35 | -0.00774719 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.00769396 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00768027 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00760986 |
| CST3 | cystatin C | -0.00760787 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00760291 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.00747753 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00746311 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00740467 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00712944 |
| RPL7A | ribosomal protein L7a | -0.00710991 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00710306 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00694736 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.00691068 |
| LMAN2 | lectin, mannose-binding 2 | -0.00684789 |
| MTCH1 | mitochondrial carrier 1 | -0.0068257 |
| RPS16 | ribosomal protein S16 | -0.0066245 |
| RPL31 | ribosomal protein L31 | -0.00662087 |
| RPS9 | ribosomal protein S9 | -0.00661965 |
| GPX4 | glutathione peroxidase 4 | -0.00655432 |
| SFXN3 | sideroflexin 3 | -0.006553 |
| PRPF6 | pre-mRNA processing factor 6 | -0.006504 |
| PRMT2 | protein arginine methyltransferase 2 | -0.00646392 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.00642302 |
| GM2A | GM2 ganglioside activator | -0.00640219 |
| CEP250 | centrosomal protein 250kDa | -0.00638488 |
| HLA-C | major histocompatibility complex, class I, C | -0.00633821 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00628302 |
| CAVIN1 | caveolae associated protein 1 | -0.00625775 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00622848 |
| RBBP7 | retinoblastoma binding protein 7 | -0.00619149 |
| CD47 | CD47 molecule | -0.00614705 |
| SSRP1 | structure specific recognition protein 1 | -0.00611644 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00602345 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | -0.00599615 |
| EXOC1 | exocyst complex component 1 | -0.00599285 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.00598448 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00594797 |
| RPS21 | ribosomal protein S21 | -0.005907 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.00576082 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00575754 |
| RPL36A | ribosomal protein L36a | -0.00573703 |