| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nimesulide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0960199 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0809574 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0679637 |
| CALD1 | caldesmon 1 | 0.0676394 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0669819 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0625852 |
| ANKRD11 | ankyrin repeat domain 11 | 0.059132 |
| LOX | lysyl oxidase | 0.056179 |
| CDH13 | cadherin 13 | 0.0517266 |
| COL1A1 | collagen, type I, alpha 1 | 0.0501712 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.049732 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0495479 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0487656 |
| MAP4 | microtubule-associated protein 4 | 0.0472608 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0465749 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0453192 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0446986 |
| VIM | vimentin | 0.0429435 |
| KAZN | kazrin, periplakin interacting protein | 0.0421652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0413187 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0397683 |
| VEGFC | vascular endothelial growth factor C | 0.0387498 |
| ANXA5 | annexin A5 | 0.0383881 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0381048 |
| RND3 | Rho family GTPase 3 | 0.0378478 |
| HELZ | helicase with zinc finger | 0.0361052 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0359912 |
| COL1A2 | collagen, type I, alpha 2 | 0.0357978 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0354995 |
| NRXN3 | neurexin 3 | 0.0354761 |
| TMEM165 | transmembrane protein 165 | 0.0352997 |
| CALU | calumenin | 0.0348369 |
| SEC24A | SEC24 family member A | 0.0346882 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0345327 |
| MMP12 | matrix metallopeptidase 12 | 0.0337549 |
| HIP1 | huntingtin interacting protein 1 | 0.0333234 |
| UBC | ubiquitin C | 0.0332162 |
| RPS19 | ribosomal protein S19 | 0.0331066 |
| STK4 | serine/threonine kinase 4 | 0.033089 |
| IL6 | interleukin 6 | 0.0328678 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0326904 |
| TPM1 | tropomyosin 1 (alpha) | 0.0324388 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0323336 |
| EGFR | epidermal growth factor receptor | 0.0323083 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0321121 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319824 |
| GPC6 | glypican 6 | 0.0317034 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031453 |
| ATXN1 | ataxin 1 | 0.0312765 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.03104 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0309989 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0304767 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0303269 |
| TXNRD1 | thioredoxin reductase 1 | 0.0302081 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0298592 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0296543 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0293007 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.029209 |
| KIF1B | kinesin family member 1B | 0.0291807 |
| LAMB3 | laminin, beta 3 | 0.0290588 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0288762 |
| FAM13A | family with sequence similarity 13, member A | 0.0284771 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0283551 |
| RTN4 | reticulon 4 | 0.0283009 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0280682 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0278901 |
| MYO9A | myosin IXA | 0.0277978 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0276615 |
| S100A10 | S100 calcium binding protein A10 | 0.0273069 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0272763 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0271891 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271651 |
| SET | SET nuclear proto-oncogene | 0.0270682 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0266936 |
| IL6ST | interleukin 6 signal transducer | 0.0263704 |
| ATXN2 | ataxin 2 | 0.0263526 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0261692 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0259797 |
| SDCBP | syndecan binding protein (syntenin) | 0.0255825 |
| ATP13A3 | ATPase type 13A3 | 0.0255371 |
| CLIC4 | chloride intracellular channel 4 | 0.0253204 |
| JMJD1C | jumonji domain containing 1C | 0.0251037 |
| RPS8 | ribosomal protein S8 | 0.0249607 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.024774 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0246913 |
| ITSN2 | intersectin 2 | 0.0245761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0243037 |
| COL3A1 | collagen, type III, alpha 1 | 0.0241131 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0240032 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.023919 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0239175 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0238245 |
| SUCO | SUN domain containing ossification factor | 0.0237902 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0237888 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0235832 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0234664 |
| PGK1 | phosphoglycerate kinase 1 | 0.0234266 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023345 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.023323 |
| USP12 | ubiquitin specific peptidase 12 | 0.0233053 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.116624 |
| CALR | calreticulin | -0.091571 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0904125 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0731882 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0722859 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0714648 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0600212 |
| SDC4 | syndecan 4 | -0.0575575 |
| ZNF395 | zinc finger protein 395 | -0.0492109 |
| VEGFA | vascular endothelial growth factor A | -0.0491874 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.047441 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0449574 |
| B2M | beta-2-microglobulin | -0.0446663 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0428693 |
| FN1 | fibronectin 1 | -0.0416623 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0400558 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0391376 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0385399 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0381326 |
| LAMB1 | laminin, beta 1 | -0.0381014 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0372228 |
| LDHA | lactate dehydrogenase A | -0.036681 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0352823 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342519 |
| HDLBP | high density lipoprotein binding protein | -0.0342483 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.033916 |
| TAGLN2 | transgelin 2 | -0.0336617 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0335146 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0333309 |
| CCNI | cyclin I | -0.0328044 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0326612 |
| MMP2 | matrix metallopeptidase 2 | -0.0325502 |
| NDRG1 | N-myc downstream regulated 1 | -0.0321739 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0319868 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0316151 |
| FLNB | filamin B, beta | -0.0310816 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0310093 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0309542 |
| COPA | coatomer protein complex, subunit alpha | -0.0305415 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0298732 |
| RRBP1 | ribosome binding protein 1 | -0.0283396 |
| HLA-A | major histocompatibility complex, class I, A | -0.028232 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0281582 |
| ENO1 | enolase 1, (alpha) | -0.0281191 |
| LMAN2 | lectin, mannose-binding 2 | -0.0280298 |
| TUBA1B | tubulin, alpha 1b | -0.0279883 |
| RPS14 | ribosomal protein S14 | -0.0275106 |
| SMAD3 | SMAD family member 3 | -0.0272668 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0270442 |
| VDAC2 | voltage-dependent anion channel 2 | -0.0269992 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0268096 |
| RPL9 | ribosomal protein L9 | -0.0265638 |
| RPL28 | ribosomal protein L28 | -0.0262528 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.026154 |
| EGR1 | early growth response 1 | -0.0261231 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0260839 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0257985 |
| ECE1 | endothelin converting enzyme 1 | -0.0253831 |
| FAM120A | family with sequence similarity 120A | -0.0253266 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0251379 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.025059 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.024746 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0245405 |
| NRBP1 | nuclear receptor binding protein 1 | -0.0244541 |
| LMNA | lamin A/C | -0.0243031 |
| SPOP | speckle-type POZ protein | -0.0242245 |
| SNX3 | sorting nexin 3 | -0.0241974 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0240353 |
| SEPTIN7 | septin 7 | -0.0233486 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0233005 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0232883 |
| TNS3 | tensin 3 | -0.0232718 |
| CCDC57 | coiled-coil domain containing 57 | -0.0232712 |
| SYNJ2 | synaptojanin 2 | -0.0229363 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0229349 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0228155 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0225589 |
| COL6A1 | collagen, type VI, alpha 1 | -0.022488 |
| RPL4 | ribosomal protein L4 | -0.0224834 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.022383 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0223828 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0221765 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0220371 |
| PFKL | phosphofructokinase, liver | -0.0219395 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0218601 |
| ZNF638 | zinc finger protein 638 | -0.0217882 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0217561 |
| TANK | TRAF family member-associated NFKB activator | -0.0217329 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0217051 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0213576 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0213201 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0212556 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0212524 |
| SP140L | SP140 nuclear body protein-like | -0.0212341 |
| PKM | pyruvate kinase, muscle | -0.0210142 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0209 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.02088 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0206459 |
| ANO6 | anoctamin 6 | -0.0205967 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0205696 |
