| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nimesulide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nimesulide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.13904 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.11344 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0988255 |
| MT2A | metallothionein 2A | 0.0881644 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.083406 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0601824 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0601195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0546531 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0519401 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0511658 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0484656 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0482626 |
| ZNF292 | zinc finger protein 292 | 0.0441061 |
| RPS12 | ribosomal protein S12 | 0.0432915 |
| RBM39 | RNA binding motif protein 39 | 0.0432837 |
| RNF145 | ring finger protein 145 | 0.0431524 |
| OGA | O-GlcNAcase | 0.0428967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.040292 |
| RPL37A | ribosomal protein L37a | 0.0374472 |
| RPS6 | ribosomal protein S6 | 0.0363461 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0361977 |
| SUCO | SUN domain containing ossification factor | 0.0354923 |
| CANX | calnexin | 0.0352715 |
| HELZ | helicase with zinc finger | 0.0351484 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337793 |
| NEK7 | NIMA-related kinase 7 | 0.0331932 |
| COG5 | component of oligomeric golgi complex 5 | 0.0326488 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032568 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0322808 |
| GOLGA4 | golgin A4 | 0.0317548 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0317178 |
| TFG | TRK-fused gene | 0.0315379 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031426 |
| FAM13A | family with sequence similarity 13, member A | 0.0309246 |
| RPL9 | ribosomal protein L9 | 0.0305559 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0304443 |
| WDR45B | WD repeat domain 45B | 0.0303903 |
| RPS2 | ribosomal protein S2 | 0.0302764 |
| RPL26 | ribosomal protein L26 | 0.0301712 |
| PTMA | prothymosin, alpha | 0.0301013 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.029262 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0291661 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0290715 |
| CD109 | CD109 molecule | 0.0289163 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286005 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0285644 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283295 |
| NUP58 | nucleoporin 58 | 0.0280981 |
| RPS8 | ribosomal protein S8 | 0.0280245 |
| SPAG9 | sperm associated antigen 9 | 0.0280152 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0278847 |
| SEPTIN7 | septin 7 | 0.0278684 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0278306 |
| XPO1 | exportin 1 | 0.0274446 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0267675 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.026729 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0261789 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0260128 |
| RPS19 | ribosomal protein S19 | 0.0260109 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0257588 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0255391 |
| RPL35A | ribosomal protein L35a | 0.025228 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0251442 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0250442 |
| RAB1A | RAB1A, member RAS oncogene family | 0.024864 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0248429 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0248077 |
| AHR | aryl hydrocarbon receptor | 0.0246874 |
| WTAP | Wilms tumor 1 associated protein | 0.0244727 |
| TPR | translocated promoter region, nuclear basket protein | 0.0244592 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0244191 |
| RPS27A | ribosomal protein S27a | 0.0243347 |
| RLF | rearranged L-myc fusion | 0.0243281 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0241936 |
| PELO | pelota homolog (Drosophila) | 0.0241733 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0240283 |
| CENPF | centromere protein F, 350/400kDa | 0.0238857 |
| CDC73 | cell division cycle 73 | 0.023759 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0237241 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0237178 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.023633 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0230655 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0230274 |
| NDRG1 | N-myc downstream regulated 1 | 0.0230085 |
| RPL30 | ribosomal protein L30 | 0.0229049 |
| SMOX | spermine oxidase | 0.0228897 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0227958 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0227735 |
| RBM25 | RNA binding motif protein 25 | 0.0227629 |
| RPS3 | ribosomal protein S3 | 0.0227122 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0226393 |
| YME1L1 | YME1-like 1 ATPase | 0.0226032 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0224904 |
| RIOK3 | RIO kinase 3 | 0.0223958 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0223073 |
| PGK1 | phosphoglycerate kinase 1 | 0.0221334 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0220578 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0218904 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0215021 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0214667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.278811 |
| FN1 | fibronectin 1 | -0.258145 |
| HMGA2 | high mobility group AT-hook 2 | -0.139101 |
| GLIS3 | GLIS family zinc finger 3 | -0.064082 |
| TMEM156 | transmembrane protein 156 | -0.0637758 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.063456 |
| ITGA1 | integrin, alpha 1 | -0.0597484 |
| STC2 | stanniocalcin 2 | -0.0595542 |
| ASPH | aspartate beta-hydroxylase | -0.0569499 |
| SYT1 | synaptotagmin I | -0.0523623 |
| TMSB10 | thymosin beta 10 | -0.0498267 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0481376 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0477855 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0472708 |
| EFNA5 | ephrin-A5 | -0.0451831 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0448413 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0437561 |
| NRP1 | neuropilin 1 | -0.0410335 |
| RAI14 | retinoic acid induced 14 | -0.0404611 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0393724 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0372175 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0358266 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0350873 |
| NTN4 | netrin 4 | -0.0348667 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0348288 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0336544 |
| ETV1 | ets variant 1 | -0.0336157 |
| POTEF | POTE ankyrin domain family, member F | -0.0317706 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0312915 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0301682 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0297002 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0287569 |
| VCL | vinculin | -0.0279343 |
| MAP1B | microtubule-associated protein 1B | -0.0278356 |
| RNF213 | ring finger protein 213 | -0.0276669 |
| IFI44L | interferon-induced protein 44-like | -0.0267859 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0265881 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0264007 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0261588 |
| TENM4 | teneurin transmembrane protein 4 | -0.0260095 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.025789 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0255127 |
| OSMR | oncostatin M receptor | -0.0253979 |
| KLHL5 | kelch-like family member 5 | -0.0253158 |
| ACTG1 | actin gamma 1 | -0.0249363 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0243524 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0237395 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0235627 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0234658 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0234311 |
| MX2 | MX dynamin-like GTPase 2 | -0.0228136 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0227546 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0224207 |
| HLA-B | major histocompatibility complex, class I, B | -0.022045 |
| RANBP17 | RAN binding protein 17 | -0.0214853 |
| RASAL2 | RAS protein activator like 2 | -0.0214785 |
| TNS3 | tensin 3 | -0.0211677 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0211412 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0211354 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0208319 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0207979 |
| EGR1 | early growth response 1 | -0.020609 |
| SEPTIN9 | septin 9 | -0.0202765 |
| CTSD | cathepsin D | -0.020178 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0201282 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0198441 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0198145 |
| MLPH | melanophilin | -0.0197046 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0196872 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0193961 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0192648 |
| AEBP2 | AE binding protein 2 | -0.0191327 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0187612 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0185832 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0184647 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0184249 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0179185 |
| FOXP1 | forkhead box P1 | -0.0179078 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0178995 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0178818 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0178473 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0177449 |
| FBN1 | fibrillin 1 | -0.0176198 |
| ABR | active BCR-related | -0.0176168 |
| PALLD | palladin, cytoskeletal associated protein | -0.0176002 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0174979 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0174127 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0173214 |
| MCL1 | myeloid cell leukemia 1 | -0.0170728 |
| FHL2 | four and a half LIM domains 2 | -0.0167897 |
| NBEA | neurobeachin | -0.0167713 |
| NXN | nucleoredoxin | -0.0167381 |
| OXR1 | oxidation resistance 1 | -0.0166224 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0164398 |
| CTSB | cathepsin B | -0.0163907 |
| IL6 | interleukin 6 | -0.0163209 |
| PRKCA | protein kinase C, alpha | -0.0161486 |
| NAV1 | neuron navigator 1 | -0.0159734 |
| SVIL | supervillin | -0.0159104 |
| CUX1 | cut-like homeobox 1 | -0.0157931 |
