Nimodipine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. (Chemical Entities of Biological Interest Ontology, CHEBI_7575)
External Link http://ctdbase.org/detail.go?type=chem&acc=D009553
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Genes

19 genes/proteins interacting with the chemical Nimodipine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CLU clusterin
CYP3A cytochrome P450, family 3, subfamily A
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DRD2 dopamine receptor D2
EGR1 early growth response 1
FOS FBJ murine osteosarcoma viral oncogene homolog
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
MAP2 microtubule-associated protein 2
NPPC natriuretic peptide C
NR1I2 nuclear receptor subfamily 1, group I, member 2
TH tyrosine hydroxylase