| Dataset | MotifMap Predicted Transcription Factor Targets |
| Category | genomics |
| Type | transcription factor |
| Description | NK2 homeobox 5|This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 1482) |
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4 target genes of the Nkx2-5 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
