| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.153581 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.119205 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.118437 |
| NAV1 | neuron navigator 1 | 0.111683 |
| DST | dystonin | 0.101049 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.10038 |
| COL5A1 | collagen, type V, alpha 1 | 0.0982134 |
| PLAT | plasminogen activator, tissue | 0.0941403 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0901659 |
| ASPH | aspartate beta-hydroxylase | 0.087448 |
| LDHA | lactate dehydrogenase A | 0.086256 |
| PODXL | podocalyxin-like | 0.0845107 |
| MAP1B | microtubule-associated protein 1B | 0.0806805 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0790918 |
| GLIS3 | GLIS family zinc finger 3 | 0.0789974 |
| CD44 | CD44 molecule (Indian blood group) | 0.0786943 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0782234 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0758172 |
| HDAC9 | histone deacetylase 9 | 0.0746083 |
| AHNAK | AHNAK nucleoprotein | 0.0743658 |
| VCL | vinculin | 0.0732715 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0703188 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0694242 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0629133 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.062263 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0622022 |
| FSTL1 | follistatin-like 1 | 0.0599559 |
| RIGI | RNA sensor RIG-I | 0.0594512 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0587918 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0585808 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0572044 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0567536 |
| PRSS23 | protease, serine, 23 | 0.0562928 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0560436 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0559292 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0549284 |
| EFNA5 | ephrin-A5 | 0.0547272 |
| POTEF | POTE ankyrin domain family, member F | 0.0537543 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0527122 |
| CYTH3 | cytohesin 3 | 0.0514384 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0472021 |
| NEK7 | NIMA-related kinase 7 | 0.0450557 |
| MT2A | metallothionein 2A | 0.0449196 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0442122 |
| PLXNA2 | plexin A2 | 0.0440768 |
| RASAL2 | RAS protein activator like 2 | 0.0438887 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0437449 |
| RUNX1 | runt-related transcription factor 1 | 0.043 |
| APP | amyloid beta (A4) precursor protein | 0.0424256 |
| CDK6 | cyclin-dependent kinase 6 | 0.0424078 |
| INTS6 | integrator complex subunit 6 | 0.0421477 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0418829 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0417472 |
| SMYD3 | SET and MYND domain containing 3 | 0.0414608 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0412116 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0411482 |
| RRM2 | ribonucleotide reductase M2 | 0.0411259 |
| FN1 | fibronectin 1 | 0.0408394 |
| SP100 | SP100 nuclear antigen | 0.0405108 |
| FLNA | filamin A, alpha | 0.0404785 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0404743 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0403378 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0395952 |
| PRELID2 | PRELI domain containing 2 | 0.0395345 |
| VEGFC | vascular endothelial growth factor C | 0.0394372 |
| CD59 | CD59 molecule, complement regulatory protein | 0.038777 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0386548 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0383106 |
| MED13L | mediator complex subunit 13-like | 0.0382242 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0382155 |
| RNF144A | ring finger protein 144A | 0.0381539 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0380896 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0378479 |
| RNF213 | ring finger protein 213 | 0.0371319 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.037114 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0364331 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0363575 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0361619 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0358668 |
| SMAD3 | SMAD family member 3 | 0.0357188 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0349876 |
| MB21D2 | Mab-21 domain containing 2 | 0.0348122 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0343331 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0341253 |
| IPO9 | importin 9 | 0.03398 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0339687 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0337667 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0332259 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0331854 |
| ERBIN | erbb2 interacting protein | 0.0330355 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0324363 |
| KIAA1549L | KIAA1549-like | 0.0323088 |
| FMN2 | formin 2 | 0.0321267 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0320869 |
| DCLK2 | doublecortin-like kinase 2 | 0.0315215 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0313863 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0308392 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0308292 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0307778 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0306326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.255734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.114638 |
| TMSB10 | thymosin beta 10 | -0.0928543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0891101 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0762499 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0697222 |
| VIM | vimentin | -0.0657547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0645207 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0600762 |
| FBN1 | fibrillin 1 | -0.0590415 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0582457 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0564994 |
| LOXL2 | lysyl oxidase-like 2 | -0.0533208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0471766 |
| COL1A2 | collagen, type I, alpha 2 | -0.0462574 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0436412 |
| NDRG1 | N-myc downstream regulated 1 | -0.0423732 |
| GOLGA4 | golgin A4 | -0.0415456 |
| CSTB | cystatin B (stefin B) | -0.0408009 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0381666 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0366074 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0356474 |
| PTMA | prothymosin, alpha | -0.0338291 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0334748 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0331707 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0313317 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.031193 |
| CD99 | CD99 molecule | -0.0306288 |
| VEGFA | vascular endothelial growth factor A | -0.0297529 |
| INSIG1 | insulin induced gene 1 | -0.0285959 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.028412 |
| LOX | lysyl oxidase | -0.0280619 |
| MMP12 | matrix metallopeptidase 12 | -0.0279233 |
| SBF2 | SET binding factor 2 | -0.0274496 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0273466 |
| CD109 | CD109 molecule | -0.0270655 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0265149 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0264922 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0262009 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0259747 |
| MYADM | myeloid-associated differentiation marker | -0.0255654 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0252367 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0248699 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0245118 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0242342 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0231441 |
| OPTN | optineurin | -0.0226596 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0225467 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0219175 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0213911 |
| CLU | clusterin | -0.0211072 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0210473 |
| HLA-B | major histocompatibility complex, class I, B | -0.0209412 |
| TPM4 | tropomyosin 4 | -0.0208652 |
| FTL | ferritin, light polypeptide | -0.0203141 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0202157 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0201395 |
| FOSL1 | FOS-like antigen 1 | -0.0201253 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0200605 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0200593 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0197759 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0194269 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0192014 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0189663 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0189521 |
| RPS27 | ribosomal protein S27 | -0.0181163 |
| PKM | pyruvate kinase, muscle | -0.0176397 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0176188 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0176099 |
| BSG | basigin (Ok blood group) | -0.0172683 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0172419 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0171764 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0171759 |
| NGLY1 | N-glycanase 1 | -0.0171537 |
| RPL34 | ribosomal protein L34 | -0.0170612 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0169854 |
| RPS6 | ribosomal protein S6 | -0.0167141 |
| MNT | MAX network transcriptional repressor | -0.0166559 |
| INSIG2 | insulin induced gene 2 | -0.016591 |
| UBC | ubiquitin C | -0.0165251 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0164101 |
| LMAN1 | lectin, mannose-binding, 1 | -0.01629 |
| KLHL24 | kelch-like family member 24 | -0.016273 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0162458 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.015937 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0155422 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0154854 |
| C1D | C1D nuclear receptor corepressor | -0.0154835 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0154394 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0154388 |
| ARRDC3 | arrestin domain containing 3 | -0.0153815 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.015352 |
| RPS19 | ribosomal protein S19 | -0.0153078 |
| ASTN2 | astrotactin 2 | -0.0152134 |
| MEF2D | myocyte enhancer factor 2D | -0.015154 |
| GDF15 | growth differentiation factor 15 | -0.0150606 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0149486 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0148683 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0147345 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0146459 |
