| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.205142 |
| NLGN1 | neuroligin 1 | 0.182083 |
| YAP1 | Yes-associated protein 1 | 0.130893 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.120721 |
| HMGA2 | high mobility group AT-hook 2 | 0.109629 |
| RRM2 | ribonucleotide reductase M2 | 0.0948649 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0941679 |
| DST | dystonin | 0.0895816 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0816271 |
| PDGFC | platelet derived growth factor C | 0.0787795 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0715918 |
| PCDH7 | protocadherin 7 | 0.070068 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0680779 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0678767 |
| ADIPOR2 | adiponectin receptor 2 | 0.0628101 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0615037 |
| INTS6 | integrator complex subunit 6 | 0.0560477 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0559561 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0542475 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0527174 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0524632 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0512662 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0497727 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0491488 |
| MYPN | myopalladin | 0.0479981 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0474446 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0457565 |
| EDARADD | EDAR-associated death domain | 0.0453175 |
| WWOX | WW domain containing oxidoreductase | 0.0448479 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0447108 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0445857 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422632 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0412706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041263 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0405038 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0404358 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0400143 |
| ECT2 | epithelial cell transforming 2 | 0.0395574 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0393755 |
| TENM3 | teneurin transmembrane protein 3 | 0.039184 |
| MTAP | methylthioadenosine phosphorylase | 0.0389671 |
| RPS12 | ribosomal protein S12 | 0.0388814 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0388507 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0387584 |
| DENND5A | DENN/MADD domain containing 5A | 0.0386187 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0381718 |
| RAD51B | RAD51 paralog B | 0.0378511 |
| CMIP | c-Maf inducing protein | 0.0378328 |
| RTN4 | reticulon 4 | 0.0376321 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0372719 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0365495 |
| ERBIN | erbb2 interacting protein | 0.0364091 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0363155 |
| RCOR1 | REST corepressor 1 | 0.0359417 |
| DIAPH3 | diaphanous-related formin 3 | 0.0359379 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.035855 |
| RASAL2 | RAS protein activator like 2 | 0.0353345 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.035078 |
| NHSL1 | NHS-like 1 | 0.0350625 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.035 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0346091 |
| TMEM41B | transmembrane protein 41B | 0.0345445 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0342676 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0342622 |
| TEAD4 | TEA domain family member 4 | 0.0342201 |
| VCL | vinculin | 0.0340848 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0339332 |
| HDAC9 | histone deacetylase 9 | 0.0335085 |
| NFIB | nuclear factor I/B | 0.0333999 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0333436 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0326727 |
| NUP98 | nucleoporin 98kDa | 0.0324079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0320481 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313787 |
| RPL9 | ribosomal protein L9 | 0.0312 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0311326 |
| CEP112 | centrosomal protein 112kDa | 0.0309826 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0303669 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.03028 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0294632 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0292353 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0288412 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0286673 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.028535 |
| HELLS | helicase, lymphoid-specific | 0.0284965 |
| CEP192 | centrosomal protein 192kDa | 0.0281375 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0281141 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0280943 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0280742 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0279262 |
| LMO7 | LIM domain 7 | 0.0278914 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0277522 |
| NEGR1 | neuronal growth regulator 1 | 0.0277136 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0276333 |
| USP34 | ubiquitin specific peptidase 34 | 0.0275567 |
| CLPTM1L | CLPTM1-like | 0.027044 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0266929 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0265527 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0258405 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0256198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21287 |
| VIM | vimentin | -0.145342 |
| AREG | amphiregulin | -0.0550123 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0535948 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0518421 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0471449 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0403335 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0402904 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0380079 |
| ANXA1 | annexin A1 | -0.037574 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367366 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0358697 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0350229 |
| HMGA1 | high mobility group AT-hook 1 | -0.0347983 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0335067 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0328958 |
| MKI67 | marker of proliferation Ki-67 | -0.0326612 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0319081 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0313694 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0298592 |
| LOC112694756 | uncharaterized LOC112694756 | -0.029463 |
| KIF5B | kinesin family member 5B | -0.0286301 |
| RPS6 | ribosomal protein S6 | -0.0277688 |
| RPL8 | ribosomal protein L8 | -0.0271958 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0266164 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0259192 |
| MATR3 | matrin 3 | -0.0258975 |
| TXNRD1 | thioredoxin reductase 1 | -0.0253684 |
| YBX1 | Y box binding protein 1 | -0.0242844 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0237052 |
| WDR45B | WD repeat domain 45B | -0.0234528 |
| GNAS | GNAS complex locus | -0.0234521 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0226076 |
| PREPL | prolyl endopeptidase-like | -0.021939 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.021636 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0214577 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0213903 |
| S100A10 | S100 calcium binding protein A10 | -0.0213636 |
| ZNF292 | zinc finger protein 292 | -0.020614 |
| TPM4 | tropomyosin 4 | -0.0205474 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0202339 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.020194 |
| BCHE | butyrylcholinesterase | -0.0198965 |
| S100A11 | S100 calcium binding protein A11 | -0.0198567 |
| SESN2 | sestrin 2 | -0.0198221 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0196332 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0195715 |
| PFN1 | profilin 1 | -0.0193557 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0191392 |
| HLA-A | major histocompatibility complex, class I, A | -0.0191254 |
| EDN1 | endothelin 1 | -0.0189031 |
| H1-0 | H1.0 linker histone | -0.0178636 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0176639 |
| TMEM123 | transmembrane protein 123 | -0.017611 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0174935 |
| PTMS | parathymosin | -0.0174488 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0172512 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.0172311 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0171993 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0169799 |
| PTMA | prothymosin, alpha | -0.0169042 |
| RPS16 | ribosomal protein S16 | -0.0168719 |
| S100A6 | S100 calcium binding protein A6 | -0.0167735 |
| SRP72 | signal recognition particle 72kDa | -0.0166661 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0166257 |
| MAP1B | microtubule-associated protein 1B | -0.0165657 |
| CPOX | coproporphyrinogen oxidase | -0.0165312 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0163844 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0162292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0162023 |
| ZFR | zinc finger RNA binding protein | -0.0162011 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0161226 |
| HDGF | hepatoma-derived growth factor | -0.0159703 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0159355 |
| ENO1 | enolase 1, (alpha) | -0.0158405 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0158346 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0157734 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0157524 |
| KLHL24 | kelch-like family member 24 | -0.0156364 |
| KLF6 | Kruppel-like factor 6 | -0.0156146 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0156021 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0155703 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0155362 |
| HDLBP | high density lipoprotein binding protein | -0.0154091 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0154011 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0153366 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0151165 |
| MAP4 | microtubule-associated protein 4 | -0.0150887 |
| HMGB1 | high mobility group box 1 | -0.0150609 |
| GOLGA4 | golgin A4 | -0.0149164 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0148894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.014802 |
| YEATS2 | YEATS domain containing 2 | -0.0146097 |
| ZFP91 | ZFP91 zinc finger protein | -0.0145599 |
| RPL34 | ribosomal protein L34 | -0.0144715 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0144348 |
| KIF2A | kinesin heavy chain member 2A | -0.0141973 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0140276 |
| THOC1 | THO complex 1 | -0.013825 |
| BTG3 | BTG family, member 3 | -0.0137839 |
