| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.195136 |
| AHNAK | AHNAK nucleoprotein | 0.153518 |
| DOCK5 | dedicator of cytokinesis 5 | 0.127262 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.121473 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.117569 |
| HMGA2 | high mobility group AT-hook 2 | 0.112571 |
| LAMA4 | laminin, alpha 4 | 0.110653 |
| FLNB | filamin B, beta | 0.105738 |
| EFNA5 | ephrin-A5 | 0.102598 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0946244 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0935449 |
| TXNRD1 | thioredoxin reductase 1 | 0.0929685 |
| SMAD3 | SMAD family member 3 | 0.0896803 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.089184 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0880952 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0826803 |
| RASAL2 | RAS protein activator like 2 | 0.082167 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0742466 |
| ASPH | aspartate beta-hydroxylase | 0.0731944 |
| POTEF | POTE ankyrin domain family, member F | 0.0725673 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0721661 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0712156 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0689349 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0674676 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0673067 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0669546 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0652402 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0651271 |
| TGM2 | transglutaminase 2 | 0.0648687 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0625497 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0611756 |
| CD44 | CD44 molecule (Indian blood group) | 0.0581332 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0567337 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0559295 |
| BMP6 | bone morphogenetic protein 6 | 0.0557752 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0550741 |
| DSPP | dentin sialophosphoprotein | 0.0544097 |
| NPSR1 | neuropeptide S receptor 1 | 0.0532684 |
| ITGA6 | integrin, alpha 6 | 0.0522761 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0522579 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0521223 |
| FMNL2 | formin-like 2 | 0.0518668 |
| ERBIN | erbb2 interacting protein | 0.05142 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.050948 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0498369 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0474233 |
| MYOF | myoferlin | 0.0471037 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0470399 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.046902 |
| BCL2L1 | BCL2-like 1 | 0.0465107 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0456822 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0450584 |
| EHBP1 | EH domain binding protein 1 | 0.0446367 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0427241 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0424048 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.042116 |
| LMO7 | LIM domain 7 | 0.0420462 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0416946 |
| LAMC2 | laminin, gamma 2 | 0.0413929 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411027 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0406125 |
| RAB10 | RAB10, member RAS oncogene family | 0.0406121 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0397422 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0392212 |
| DST | dystonin | 0.0386107 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0385703 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.038551 |
| VCAN | versican | 0.0385012 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377123 |
| FOXO1 | forkhead box O1 | 0.0372408 |
| HDAC9 | histone deacetylase 9 | 0.0367721 |
| MYO1E | myosin IE | 0.0363151 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0362554 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0361382 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0360107 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0340775 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0337065 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0332493 |
| GDA | guanine deaminase | 0.033191 |
| ABLIM1 | actin binding LIM protein 1 | 0.0331032 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0329944 |
| SEPTIN9 | septin 9 | 0.0328678 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0327704 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0322058 |
| PRELID2 | PRELI domain containing 2 | 0.0319782 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.031798 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0314112 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0313785 |
| DSG2 | desmoglein 2 | 0.0313758 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0305303 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0304897 |
| FAT1 | FAT atypical cadherin 1 | 0.030131 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.030034 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.029996 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0299922 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0296348 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0296268 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0295015 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0294988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.170246 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.13275 |
| TMSB10 | thymosin beta 10 | -0.0965757 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0655895 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0625292 |
| EGR1 | early growth response 1 | -0.0574925 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0564475 |
| MXD1 | MAX dimerization protein 1 | -0.0556645 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0501327 |
| B2M | beta-2-microglobulin | -0.0469047 |
| FTL | ferritin, light polypeptide | -0.0426878 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0367291 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0360888 |
| FOXO3 | forkhead box O3 | -0.0359556 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0350807 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0338822 |
| GNAS | GNAS complex locus | -0.0327731 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0326384 |
| RPL35A | ribosomal protein L35a | -0.031224 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0302723 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0301606 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0295551 |
| FOSL1 | FOS-like antigen 1 | -0.0291006 |
| TMEM165 | transmembrane protein 165 | -0.0280524 |
| TPM4 | tropomyosin 4 | -0.0278881 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0270504 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0265466 |
| RPS13 | ribosomal protein S13 | -0.0259037 |
| RPL34 | ribosomal protein L34 | -0.0256248 |
| RPL30 | ribosomal protein L30 | -0.025006 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0247926 |
| S100A6 | S100 calcium binding protein A6 | -0.0247455 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245829 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0244254 |
| HMGA1 | high mobility group AT-hook 1 | -0.0243511 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0240577 |
| MUC17 | mucin 17, cell surface associated | -0.0237391 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237243 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.023556 |
| ARF4 | ADP-ribosylation factor 4 | -0.0229034 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0228688 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0224059 |
| TMEM41B | transmembrane protein 41B | -0.0222807 |
| MCU | mitochondrial calcium uniporter | -0.02228 |
| SRP54 | signal recognition particle 54kDa | -0.0220099 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0213275 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0212831 |
| HLA-A | major histocompatibility complex, class I, A | -0.0211658 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0211451 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0211341 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0208785 |
| PTMA | prothymosin, alpha | -0.0206516 |
| MORF4L2 | mortality factor 4 like 2 | -0.0205075 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.020338 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0198894 |
| RPL26 | ribosomal protein L26 | -0.0198462 |
| UPP1 | uridine phosphorylase 1 | -0.0198201 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0197785 |
| RPS21 | ribosomal protein S21 | -0.0195739 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0195171 |
| SPAG9 | sperm associated antigen 9 | -0.019267 |
| NUP58 | nucleoporin 58 | -0.0192386 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0188938 |
| THBD | thrombomodulin | -0.0187763 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0186275 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0185182 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0184336 |
| CD164 | CD164 molecule, sialomucin | -0.018126 |
| RPS8 | ribosomal protein S8 | -0.0179269 |
| RPS25 | ribosomal protein S25 | -0.0177279 |
| CLINT1 | clathrin interactor 1 | -0.0176588 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0173168 |
| RIOK3 | RIO kinase 3 | -0.0171362 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0168368 |
| HLA-E | major histocompatibility complex, class I, E | -0.016825 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0167466 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0164681 |
| CD63 | CD63 molecule | -0.0162868 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0162808 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0158483 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0158237 |
| RPLP2 | ribosomal protein, large, P2 | -0.015542 |
| RPS12 | ribosomal protein S12 | -0.0155294 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0154823 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0154233 |
| RPS20 | ribosomal protein S20 | -0.0153378 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0153356 |
| RPL36A | ribosomal protein L36a | -0.0152261 |
| COG5 | component of oligomeric golgi complex 5 | -0.0152098 |
| SUCO | SUN domain containing ossification factor | -0.0151496 |
| RPL9 | ribosomal protein L9 | -0.015115 |
| RPS24 | ribosomal protein S24 | -0.0149436 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.014749 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -0.0147486 |
| RBM25 | RNA binding motif protein 25 | -0.0147049 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.014676 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0145465 |
| KIF5B | kinesin family member 5B | -0.0145441 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0144059 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0143735 |
