| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.130678 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.103539 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0659826 |
| GPC6 | glypican 6 | 0.0655255 |
| EXOC4 | exocyst complex component 4 | 0.0606921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0577511 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0557818 |
| NAV1 | neuron navigator 1 | 0.0519703 |
| ACTN1 | actinin, alpha 1 | 0.051304 |
| TLE4 | transducin-like enhancer of split 4 | 0.0510788 |
| SMYD3 | SET and MYND domain containing 3 | 0.0502683 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0500532 |
| DST | dystonin | 0.0498106 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0495077 |
| VCL | vinculin | 0.0489103 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.046655 |
| TMEM178B | transmembrane protein 178B | 0.0456186 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0453648 |
| MACROD2 | MACRO domain containing 2 | 0.0452904 |
| UTRN | utrophin | 0.0442508 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0439176 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.041304 |
| MT2A | metallothionein 2A | 0.0410954 |
| APP | amyloid beta (A4) precursor protein | 0.0410838 |
| LDHA | lactate dehydrogenase A | 0.0409997 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0389891 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0381583 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.036986 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0366002 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0354592 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0352845 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0350029 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0342688 |
| PRELID2 | PRELI domain containing 2 | 0.0337235 |
| FRMD5 | FERM domain containing 5 | 0.0332341 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0332051 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0329378 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0328229 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0326915 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0324715 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0324623 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0322254 |
| ATXN1 | ataxin 1 | 0.0317342 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0312541 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0311464 |
| PAX3 | paired box 3 | 0.0309514 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0306853 |
| CLIC4 | chloride intracellular channel 4 | 0.0304695 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0302188 |
| INTS6 | integrator complex subunit 6 | 0.0301269 |
| NAV2 | neuron navigator 2 | 0.0298234 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0297299 |
| SETBP1 | SET binding protein 1 | 0.0296437 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0292273 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0289799 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0287432 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0282575 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277279 |
| MITF | microphthalmia-associated transcription factor | 0.0272156 |
| NRXN3 | neurexin 3 | 0.0271974 |
| ASPH | aspartate beta-hydroxylase | 0.027 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0269635 |
| GAS7 | growth arrest-specific 7 | 0.0268354 |
| USP53 | ubiquitin specific peptidase 53 | 0.0264151 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0262751 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.025664 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0255184 |
| ZYX | zyxin | 0.0252313 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0250824 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0249261 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248483 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0247795 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0246985 |
| SHISA5 | shisa family member 5 | 0.0246124 |
| MED13L | mediator complex subunit 13-like | 0.0244673 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.0239745 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0238831 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0238407 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0236631 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0234181 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0232091 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0230604 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0227176 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0225877 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0225786 |
| FAT1 | FAT atypical cadherin 1 | 0.0223181 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0221572 |
| PCDH7 | protocadherin 7 | 0.021883 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0218341 |
| ACTG1 | actin gamma 1 | 0.0216691 |
| EFNA5 | ephrin-A5 | 0.0213723 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0211773 |
| FRMD4A | FERM domain containing 4A | 0.021156 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0210953 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0206152 |
| NHSL1 | NHS-like 1 | 0.0205647 |
| RNF213 | ring finger protein 213 | 0.0205418 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0202771 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.019953 |
| IPO9 | importin 9 | 0.0198957 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118516 |
| VGF | VGF nerve growth factor inducible | -0.116562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0995218 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0983587 |
| NDRG1 | N-myc downstream regulated 1 | -0.097332 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0965958 |
| FN1 | fibronectin 1 | -0.0891843 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0884009 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0798291 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0742581 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0715261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0665072 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0654401 |
| SCFD2 | sec1 family domain containing 2 | -0.059971 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0596307 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0579283 |
| NLGN1 | neuroligin 1 | -0.055908 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0547348 |
| ENO1 | enolase 1, (alpha) | -0.0534404 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0525816 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0524273 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0516695 |
| CD109 | CD109 molecule | -0.0487201 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0471643 |
| RUNX1 | runt-related transcription factor 1 | -0.0465934 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0454764 |
| GOLGA4 | golgin A4 | -0.044501 |
| NBAS | neuroblastoma amplified sequence | -0.0439033 |
| GDF15 | growth differentiation factor 15 | -0.0434606 |
| CENPF | centromere protein F, 350/400kDa | -0.0385406 |
| CANX | calnexin | -0.0376081 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.036217 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0350738 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0349927 |
| WDR45B | WD repeat domain 45B | -0.0347696 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0346707 |
| PTK2 | protein tyrosine kinase 2 | -0.0343168 |
| HLA-B | major histocompatibility complex, class I, B | -0.0341799 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0331808 |
| PTMA | prothymosin, alpha | -0.0331596 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331281 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0330593 |
| DCT | dopachrome tautomerase | -0.0326394 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0324971 |
| RRBP1 | ribosome binding protein 1 | -0.0323424 |
| CALR | calreticulin | -0.0311602 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310742 |
| CTTNBP2 | cortactin binding protein 2 | -0.0299041 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0288405 |
| MEF2A | myocyte enhancer factor 2A | -0.0286422 |
| TMEM123 | transmembrane protein 123 | -0.028507 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0282526 |
| POM121 | POM121 transmembrane nucleoporin | -0.0282281 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0273308 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027147 |
| TMSB10 | thymosin beta 10 | -0.0271396 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0261695 |
| OXR1 | oxidation resistance 1 | -0.0260105 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0259366 |
| FAM162A | family with sequence similarity 162, member A | -0.0258058 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0254932 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0252448 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0251065 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0248968 |
| RNF24 | ring finger protein 24 | -0.0244743 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0240122 |
| PLIN2 | perilipin 2 | -0.0237042 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0235244 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0234698 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.023296 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0231545 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0223253 |
| PYGB | phosphorylase, glycogen; brain | -0.0221737 |
| ZNF827 | zinc finger protein 827 | -0.0218243 |
| NAV3 | neuron navigator 3 | -0.0216991 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0214475 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0208937 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.020841 |
| MTDH | metadherin | -0.020577 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.020444 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.020218 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0202056 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.0201639 |
| ZC3H7A | zinc finger CCCH-type containing 7A | -0.0201606 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0200045 |
| CDK19 | cyclin-dependent kinase 19 | -0.0197724 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.019526 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0195015 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0193999 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0191756 |
| AK2 | adenylate kinase 2 | -0.0188629 |
| FMNL2 | formin-like 2 | -0.0188162 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0188122 |
| GHR | growth hormone receptor | -0.0187693 |
| ZNF292 | zinc finger protein 292 | -0.018764 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0187236 |
| CSNK1E | casein kinase 1, epsilon | -0.0186527 |
| PARVB | parvin, beta | -0.0185821 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0184582 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0184051 |
