| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Norepinephrine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.148992 |
| EFNA5 | ephrin-A5 | 0.113987 |
| ASPH | aspartate beta-hydroxylase | 0.11105 |
| MT2A | metallothionein 2A | 0.10786 |
| AHNAK | AHNAK nucleoprotein | 0.100237 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.09655 |
| SMAD3 | SMAD family member 3 | 0.0883074 |
| MT1X | metallothionein 1X | 0.0870966 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.082317 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0758893 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0729364 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0727942 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0703912 |
| APP | amyloid beta (A4) precursor protein | 0.0659221 |
| RAD51B | RAD51 paralog B | 0.0649635 |
| TGM2 | transglutaminase 2 | 0.0604813 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.057981 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0577366 |
| NRG3 | neuregulin 3 | 0.0557085 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0552521 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0550938 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0549017 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0544801 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0534657 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0527789 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0525819 |
| FAM13A | family with sequence similarity 13, member A | 0.0505732 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0502194 |
| CCNY | cyclin Y | 0.0497737 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0486561 |
| AREG | amphiregulin | 0.0472331 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0469198 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0465356 |
| ITGA6 | integrin, alpha 6 | 0.045669 |
| DST | dystonin | 0.0449856 |
| MCL1 | myeloid cell leukemia 1 | 0.0449852 |
| TOP1 | topoisomerase (DNA) I | 0.0445141 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0439763 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0434811 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0431237 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0426368 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0423764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0421617 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0417752 |
| PRELID2 | PRELI domain containing 2 | 0.0414209 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0412692 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0402685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0400853 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0396296 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0387161 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0374038 |
| PCBP2 | poly(rC) binding protein 2 | 0.0372982 |
| USP3 | ubiquitin specific peptidase 3 | 0.0370477 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0370252 |
| PARD3 | par-3 family cell polarity regulator | 0.0366026 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0356087 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0353997 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0352504 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0348332 |
| ATXN1 | ataxin 1 | 0.0339468 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336549 |
| H1-0 | H1.0 linker histone | 0.0335072 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0334463 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0331888 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0331185 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0326429 |
| ZNF292 | zinc finger protein 292 | 0.0314949 |
| PDZD8 | PDZ domain containing 8 | 0.0308919 |
| LMO7 | LIM domain 7 | 0.0308106 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0306344 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0306336 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0304594 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0302623 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.029377 |
| MYO10 | myosin X | 0.0293646 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0288067 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0281932 |
| BCL2L1 | BCL2-like 1 | 0.0280002 |
| FAT1 | FAT atypical cadherin 1 | 0.0277321 |
| AHR | aryl hydrocarbon receptor | 0.0276432 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0273396 |
| SMYD3 | SET and MYND domain containing 3 | 0.0273188 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0272591 |
| BICC1 | BicC family RNA binding protein 1 | 0.0271436 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0271317 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0269345 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0268634 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0267735 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0267231 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0263981 |
| OGA | O-GlcNAcase | 0.0263151 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0260154 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0259839 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.025974 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0255535 |
| FAM3C | family with sequence similarity 3, member C | 0.0254461 |
| TGFB2 | transforming growth factor, beta 2 | 0.0249092 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248252 |
| RBM39 | RNA binding motif protein 39 | 0.0248247 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0246801 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.118603 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.113623 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0949528 |
| CP | ceruloplasmin (ferroxidase) | -0.082947 |
| LAMB3 | laminin, beta 3 | -0.0802262 |
| MMP7 | matrix metallopeptidase 7 | -0.063138 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0605141 |
| HLA-A | major histocompatibility complex, class I, A | -0.0575644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0540478 |
| ACTG1 | actin gamma 1 | -0.053195 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0505278 |
| KLF6 | Kruppel-like factor 6 | -0.0496215 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0492832 |
| HLA-E | major histocompatibility complex, class I, E | -0.0472288 |
| SPAG9 | sperm associated antigen 9 | -0.0401776 |
| GOLGB1 | golgin B1 | -0.0394115 |
| TMSB4X | thymosin beta 4, X-linked | -0.0390582 |
| TMSB10 | thymosin beta 10 | -0.0359938 |
| PLAU | plasminogen activator, urokinase | -0.0353406 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0340294 |
| TPM4 | tropomyosin 4 | -0.0328677 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0322903 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0322773 |
| S100A6 | S100 calcium binding protein A6 | -0.0314158 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304997 |
| GNAS | GNAS complex locus | -0.0302119 |
| ANXA2 | annexin A2 | -0.0297598 |
| HMGA1 | high mobility group AT-hook 1 | -0.02932 |
| DTNA | dystrobrevin, alpha | -0.0293026 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0292291 |
| B2M | beta-2-microglobulin | -0.0290136 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.028761 |
| VIM | vimentin | -0.0272884 |
| RPS29 | ribosomal protein S29 | -0.0265149 |
| SYNRG | synergin, gamma | -0.0262313 |
| EGR1 | early growth response 1 | -0.0259198 |
| CSTB | cystatin B (stefin B) | -0.0257816 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0257469 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254971 |
| OPTN | optineurin | -0.0253663 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0250346 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0248218 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0247879 |
| RRBP1 | ribosome binding protein 1 | -0.0241374 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0241065 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.023748 |
| RPL34 | ribosomal protein L34 | -0.0235629 |
| S100A10 | S100 calcium binding protein A10 | -0.0234112 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234057 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0227514 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0227307 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0227038 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0225661 |
| RPL35A | ribosomal protein L35a | -0.0222185 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0218051 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0217386 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0212981 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0212287 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0211853 |
| SQSTM1 | sequestosome 1 | -0.0209135 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.02057 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0202655 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0201296 |
| MUC4 | mucin 4, cell surface associated | -0.0199999 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0196394 |
| HLA-C | major histocompatibility complex, class I, C | -0.019604 |
| CEP350 | centrosomal protein 350kDa | -0.0195327 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0195308 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0195179 |
| FNIP1 | folliculin interacting protein 1 | -0.0193661 |
| EMP1 | epithelial membrane protein 1 | -0.0191691 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0190595 |
| RPS8 | ribosomal protein S8 | -0.0188727 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0188295 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0186868 |
| LASP1 | LIM and SH3 protein 1 | -0.018602 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0185894 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0185302 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.018303 |
| CLTC | clathrin, heavy chain (Hc) | -0.0181994 |
| FBXO11 | F-box protein 11 | -0.0179941 |
| TMEM165 | transmembrane protein 165 | -0.017761 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0175561 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0174752 |
| PTMA | prothymosin, alpha | -0.0168874 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0167223 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.01659 |
| CCND1 | cyclin D1 | -0.0164945 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0164882 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0164288 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0163683 |
| MX2 | MX dynamin-like GTPase 2 | -0.0162474 |
| TOB2 | transducer of ERBB2, 2 | -0.0160837 |
| RPL31 | ribosomal protein L31 | -0.0160475 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0159631 |
| RPL37A | ribosomal protein L37a | -0.0157274 |
| AGR2 | anterior gradient 2 | -0.0156827 |
| CLIC4 | chloride intracellular channel 4 | -0.0156186 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0155985 |
| PLAT | plasminogen activator, tissue | -0.0155324 |
